Assistant Professor of Neurology @ColumbiaMed #PopulationGenetics #Epidemiology #Neuroscience #Alzheimer #ENDALZ ๐Ÿณ๏ธโ€๐ŸŒˆ

Joined October 2021
33 Photos and videos
Pinned Tweet
๐˜ผ๐™‹๐™Š๐™€-ฮต4 and ฮต2 effect in Alzheimer's Disease varies across populations! Check our findings in the largest collection of Hispanics/Latinos now published in @alzdemjournals ๐Ÿ“ฐ alz-journals.onlinelibrary.wโ€ฆ
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20 Nov 2025
Check out our lab's latest software! ๐—ฆ๐—”๐—š๐—” runs ๐—ด๐—ฒ๐—ป๐—ผ๐—บ๐—ฒ๐˜„๐—ถ๐—ฑ๐—ฒ ๐—ฎ๐˜€๐˜€๐—ผ๐—ฐ๐—ถ๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ฎ๐—ป๐—ฎ๐—น๐˜†๐˜€๐—ฒ๐˜€ with a simple one-line command! Anyone can access complex genetic analyses ๐Ÿ™Œ [developed by the talented Basilio Cieza] ๐Ÿ“Œbiorxiv.org/content/10.1101/โ€ฆ
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Africa is making history with its first large-scale Alzheimerโ€™s datasets ๐Ÿง โœจ Read more in the link!
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GiusTo Lab retweeted
Presenting my preliminary results of APOE e4 and Ptau 217 over cognition in quechua and aymara population from GAPP study at #AAIC25 in Toronto. Thanks to @GiusToLab, @NiltonCustodio8 @marciosotoanari
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GiusTo Lab retweeted
How does APOE status impact AD risk in Hispanics/Latinos? Research in A&D report APOE ฮต4 shows a heterogeneous effect on ADRD risk across Hispanic/Latino populations, with the strongest associations in Peruvians/Bolivians #AlzResearch alz-journals.onlinelibrary.wโ€ฆ
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GiusTo Lab retweeted
What does heritability mean as measured multiple ways and what does it mean for our understanding of Alzheimer's? Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review medrxiv.org/content/10.1101/โ€ฆ
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15 Apr 2025
Took a minute (4 years๐Ÿ˜…), but we made it! We studied the heterogeneity of APOE and Alzheimer's Disease risk using the largest collection of Hispanic/Latino studies - an amazing collective effort๐ŸŽ‰ alz-journals.onlinelibrary.wโ€ฆ
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29 Mar 2025
v nice thread
I wrote about how population stratification in genetic analyses led to a decade of false findings and almost certainly continues to bias emerging results. But we are starting to have statistical tools to sniff it out. A ๐Ÿงต:
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18 Mar 2025
Congrats to our star clinical coordinator Jennifer Ortega Morales - she matched yesterday for the Internal Medicine Residency Program! #proudPI
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14 Jan 2025
Finally out our paper on ptau217 and AD in Peruvian populations! A huge effort for the GAPP study, an exceptional cohort of participants from Lima, Arequipa and Puno with deep phenotyping, genetics, plasma and serum available for the scientific community! alzres.biomedcentral.com/artโ€ฆ
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15 Jan 2025
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Closing day at the Brain Ageing and Dementia in LMICs 2024 conference in Nairobi, Kenya ๐Ÿ‡ฐ๐Ÿ‡ช Dr. @pericakvance taking the stage to present our @NIHAging funded DAWN study for which we have been recruiting thousands of seniors in US and Africa thedawnstudy.com
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see you in Vienna! #ENDALZ ๐Ÿ—“๏ธprogram here: adpd.kenes.com/scientific-prโ€ฆ
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We now have a zebrafish model ๐ŸŸ to better dissect the genetics underpinning Fetal Alcohol Spectrum Disorders #FASD - thanks to @CaKizil @gaattagca @NIAAAnews preprint here ๐Ÿ‘‡๐Ÿผ biorxiv.org/content/10.1101/โ€ฆ
A new project from our lab! Fascinating #admixture study on this underrepresented South African population and the risk profile for Fetal alcohol spectrum disorders #FASD. 1% to 5% of U.S. first graders have FASD! @NIAAAnews medrxiv.org/content/10.1101/โ€ฆ
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30 Jul 2024
Check out our poster #338 showing the performance of ptau-217 for #Alzheimer in a large South American cohort #AAIC2024 #biomarkers
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29 Jul 2024
Living our best life with AAIC boxed lunch ๐Ÿ˜‚
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29 Jul 2024
Join us today at 4:15 pm EST! #AAIC2024
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GiusTo Lab retweeted
1/ Even in the era of single-cell RNAseq, bulk-RNAseq data are still very valuable. 10 tools/papers related to bulk-RNAseq deconvolution.๐Ÿงต
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16 Jul 2024
I'm chairing the "๐—š๐—ฒ๐—ป๐—ผ๐—บ๐—ถ๐—ฐ๐˜€ ๐—ผ๐—ณ ๐—”๐——๐—ฅ๐—— ๐—ถ๐—ป ๐—ฑ๐—ถ๐˜ƒ๐—ฒ๐—ฟ๐˜€๐—ฒ ๐—ฝ๐—ผ๐—ฝ๐˜‚๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€" session at the upcoming #AAIC2024 in Philly ! Come visit us! ๐Ÿ“…Monday, July 29th โฒ๏ธ4:15-5:45pm EST โ„น๏ธ aaic.alz.org/program/scientiโ€ฆ
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