After the US government put a health warning on IARC's low quality research, @zaruk wonders what a post-IARC world will look like. Less fear, ignorance or useless lawsuits It will be better and no one will notice when the cancer agency crawls into oblivion thefirebreak.org/p/welcoming…

1/7 My 7sugar infographics are back! They help people with T2D predict the glycaemic consequences of dietary choices. Carbs are the main drivers of blood sugar. Here I reinterpret the glycaemic load as approx. 4g teaspoons of table sugar. Freely available phcuk.org/sugar/

🚨 New #FeldmanProtocol Dropping special guest Peter Ballerstedt (PhD) @GrassBased 🌾 Why can't a plant-only world work? 🧬 How do ruminants make all amino acids? 🔬 How does "crude protein" mislead us all? 🌿 What makes blue zone data unreliable? Full episode next tweet 👇

Thank goodness Gary Taubes @garytaubes chose physics over medicine and then came from there to science journalism. His latest book amazon.com/Rethinking-Diabet… is another masterpiece. His ability to research the history of the medical topics that interest him and to present the material with novelty, accuracy and clarity in a most engaging way, is of the highest quality. I learned two crucial facts from his deep dive into the historical evolution of the management of diabetes of both types. First, when insulin was discovered in 1921, it produced an instant miracle cure by saving the lives of those who were unable to produce any insulin, those with type 1 diabetes. But the honeymoon period lasted just 15-20 years after which insulin-treated diabetics began to present with premature atherosclerosis. By which time, the prevailing opinion had become that this was caused by a diet too high in fat. For the life-saving insulin had to be innocent - Remember Semmelweis and the doctor-caused disease that he decribed. Thus the prescribed treatment for diabetics of both types became a low-fat high-carbohydrate diet, just as was being prescribed to cardiac patients to prevent disease progression. Second, Taubes made the telling point, overlooked by many, that one of two diets is prescribed to prevent atherosclerosis in normal persons and in those with diabetes. There are the fat substitution diet and the low-fat diet - and they act quite different especially in persons with insulin-resistance or type 2 diabetes. In the fat substitution diet, saturated fats are replaced with polyunsaturated fats. There have been numerous long-term multi-million $ trials of this dietary intervention. They have all failed miserably to show benefit and some have caused harm openheart.bmj.com/content/8/…. Thus we know that the fat substitution diet is a complete failure and may even be harmful. In the low-fat diet, a large portion of the fat in the diet is replaced with carbohydrate. Whilst this diet may be acceptable for those who are not insulin-resistant, for those who are diabetic, it has to be the worst possible choice. Because, with time as the patient becomes progressively more insulin resistant, he/she will require ever larger doses of insulin to maintain blood glucose concentrations in a reasonable range. And didn't the problem of atherosclerosis first appear in middle-aged type 1 diabetics who had been treated with insulin for some decades? Importantly there has never been a major multi-million $ trial of the effects of a low-fat high-carbohydrate diet on the development of atherosclerosis in otherwise health individuals. But there has been one such trial on weight loss and cardiovascular outcomes in diabetic patients - The LookAhead trial. The study was terminated after 9.5 years because it was considered "futile" to continue as there was no evidence that the diet produced any protection from coronary heart disease. The point is that if you have diabetes, you're probably not best advised to adopt either a fat-substitution diet or a low-fat high-carbohydrate diet, since neither is likely to produce any health benefits and both could be harmful. @BenBikmanPhD @zoeharcombe @bigfatsurprise @AKoutnik @LoreofRunning1 @sweatscience @drericwestman @markkaplan20