Hard to disagree… ☺

We believe that the beauty of olefin metathesis lies in its remarkable flexibility and versatility. In 2018 we explored the chain clipping/ring contraction with unprotected dienes. To probe the above strategy, we chose to start with precursors of macrocyclic musks. To shift alkenes, we opted to use Grotjahn’s “alkene zipper” catalyst (Ru(Cp), a purchasable complex that has been shown to promote a that has been shown to promote E-selective isomerization. doi.org/10.1002/chem.2018007…

Is cyclic (alkyl)(amino)carbene a new N-heterocyclic carbene? “The development pathway of any catalyst family can be—through a somewhat stretched comparison—likened to the evolution of a family of aircraft. When analyzing the silhouettes and designs of major fighter aircraft from 1938 to 1942, significant similarities are readily apparent. All of them—whether the Spitfire with its mathematically elegant elliptical wings or the more angular designs of Professor Messerschmitt—were, with only a few exceptions, low-wing monoplanes with retractable landing gear and inline engines driving a propeller…” Read more about our view on the development of NHC and CAAC ruthenium olefin metathesis catalysts in our Opinion in Trends in Chemistry (link in a comment). #reviews #chemistry (Airplanes artwork © @GlobalPower123 FB profile)