Mpox continues to spread in many communities. Tecovirimat has activity against orthopoxviruses in vitro. In a phase 3 trial involving patients with acute mpox, tecovirimat showed no evidence of clinical activity. Full STOMP/A5418 trial results: https://nej.md/4rdlMA9
ALT Original Article | Feb 26, 2026
Tecovirimat for the Treatment of Mpox
Figure 2A. Primary Outcome Measure, Clinical Resolution