Leslie Griffith’s Lab, Brandeis University, Neuroscience.
Joined May 2020
- Tweets 77
- Following 131
- Followers 234
- Likes 31
5 Photos and videos
31 May 2023
Congratulations to @Neuro_Mohamed on defending your thesis and your last day in the Griffith Lab! We are so proud of all you've accomplished and you will be missed greatly!
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21 Dec 2022
A new paper from our lab is out!
20 Dec 2022
Subtype-specific roles of ellipsoid body ring neurons in sleep regulation in Drosophila @GriffithFlyLab jneurosci.org/content/early/…
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13 Dec 2022
Leslie from Brandeis Ugly Sweater Contest 2022 ... We should have won! 🤣
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Real Houseflies of Brandeis retweeted
26 Oct 2022
Been working with flies for a long time, didn’t think I would be surprised by anything flies did. But, wow..
Paper out!!! #Drosophila has muscles that attach to their retinas, which it uses to move its photoreceptor sheet in ways that resemble vertebrate eye movements @Nature nature.com/articles/s41586-0…
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Real Houseflies of Brandeis retweeted
31 Aug 2022
New review paper from the @MarderLab! Latest insights from small rhythmic neural circuits on individual variability, resilience and neuromodulation of neurons and neural networks. sciencedirect.com/science/ar…
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30 Aug 2022
Check out our latest work by Michael Hobin et al. !!!
30 Aug 2022
microRNA regulation of sleep in the fruit fly @GriffithFlyLab @Neuro_Mohamed @EmaCiencia @urccbrandeis @BrandeisNeuro @BrandeisScience
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Real Houseflies of Brandeis retweeted
18 Aug 2022
Our lab @Brandeis (~Boston) now hiring a Research Tech. We study how flies/mosquitoes sense the world using molbio/genetics. Whether goal is PhD/MD program in ≥2 yrs (recent ex-techs in PhD (UC Berk.,UVM), MD/PhD (BU) programs) or long-term, contact us. brandeis.wd5.myworkdayjobs.c…
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Real Houseflies of Brandeis retweeted
18 Jul 2022
How does multisensory learning improve memory performance, for even the individual sensory cues?
Zeynep Okray @z_okray, Pedro Jacob, Ciara Stern, Kieran Desmond, @_Nils_Otto_
and @paovargtz show how.
biorxiv.org/content/10.1101/…
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30 Jun 2022
The Katz lab in Brandeis University is looking for postdocs, see the ad for more details. P.S. we are looking for postdocs as well!
The Katz Lab is looking for postdoctoral researchers!
katzlab.squarespace.com/
Please RT or share with anyone who might be interested
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Real Houseflies of Brandeis retweeted
16 Jun 2022
#JNeurosci: @Neuro_Mohamed et al. @BrandeisU developed a method to study memory formation in excised brains from Drosophila melanogaster. This method can reproduce the salient features of memory formation that have been identified in intact animals.
jneurosci.org/lookup/DOI/10.…
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Real Houseflies of Brandeis retweeted
14 Jun 2022
Lab's latest pub🍾!! Inversion of the response sign in a single olfactory neuron reverses olfactory preference behavior! Unexpected - we thought it was an artifact for the longest time. Congrats to all authors and esp Munzareen Khan for seeing this through! Preprint tweetorial 👇🏽
14 Jun 2022
Context modulates valence of individual odorants in #Celegans: context-dependent engagement of distinct signaling pathways within a single sensory neuron type can switch #olfactory preference #behavior from attraction to aversion @SenguptaLab #PLOSBiology plos.io/3zBEfPl
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27 May 2022
The final version of @Neuro_Mohamed’s paper is officially out. In an ex vivo model of Drosophila associative memory, pairing activation of the CS pathway with activation of the US pathway forms a pairing-dependent plasticity (PDP). (1/5) jneurosci.org/content/42/21/…
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27 May 2022
PDP localizes in the mushroom body a'3 compartment, but increasing the intensity of the CS pathway electrical stimulation extends PDP to the a3 compartment as well. PDP also requires an intact 3'UTR of CaMKII mRNA, which is important for localizing CaMKII to the synapse. (4/5)
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27 May 2022
Finally, the formation of PDP requires nighttime sleep, as 12-hour sleep deprivation at night blocks PDP formation in the next morning. However, even in the sleep deprived flies, a minimum of 2 hours of rest in the morning recovers the ability for PDP formation. (5/5)
Real Houseflies of Brandeis retweeted
18 May 2022
📢 Special Seminar by Leslie Griffith @GriffithFlyLab on new mechanisms for generating subcellular biochemical asymmetries relevant to neuronal function. 🔥 Don't miss it‼️
🗓️ June 8th, 16:00h @NeuroAlc
@CSIC @UniversidadMH @CSICval
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10 May 2022
Our new paper is officially out:
authors.elsevier.com/c/1f2ob…
Local enrichment of CaMKII in MB is achieved via enhanced axoplasmic translation of CaMKII mRNA, through a mechanism requiring the RNA-binding protein Mub and a 23-base Mub-recognition element in the CaMKII 3′ UTR.
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10 May 2022
Perturbation of either dramatically reduces axonal, but not somatic, CaMKII protein without altering the distribution or amount of mRNA in vivo. This axonal enrichment of CaMKII is necessary for cellular plasticity and associative memory formation.
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Real Houseflies of Brandeis retweeted
21 Apr 2022
Thanks everyone! I'm truly honored and excited to be IBANGS President-elect. Let me tell you why... 🧵
20 Apr 2022
Big News! IBANGS Election Results. Congratulations President-Elect: Karla Kaun, Brown University and Member-At-Large: Paul Meyer, University of Buffalo. We look forward to you tenure. @karlakaun @pauljohnmeyer @BrownUniversity @UBuffalo
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