@IGM_YoungLab profile picture
NUBI_YoungLab @IGM_YoungLab

The Young Lab are based at Newcastle University. Our aim is to understand, and ultimately prevent, the cartilage loss that typifies osteoarthritis

Joined October 2018
  • Tweets 296
  • Following 224
  • Followers 303
34 Photos and videos
Transcriptomic profiling confirms microRNA-140 is more functional in j... sciencedirect.com/science/ar…
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Delighted this #microRNA 140 paper is now published in Osteoarthritis and Cartilage doi.org/10.1016/j.joca.2025.… Thank you to all involved, and to the journal and reviewers #spatialTranscriptomics
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NUBI_YoungLab retweeted
Arthritis UK@arthritisukorg
14 Oct 2025
We are Arthritis UK. Our name may have changed, but our mission hasn't. We won't rest until everyone with arthritis has access to the support and treatment they need to live the life they choose. Learn more: arthritis-uk.org #ArthritisUK
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Thank you to the North East @NRAS_UK volunteer group for the kind hospitality and friendly questioning when hearing about some of the ongoing research of the @IGM_Skeletal
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NUBI_YoungLab retweeted
Claudia Schneider@CSchneiderNCL
4 Mar 2025
We have a 4 year PhD position available to study the impact of the RNA exosome on ribosome specialisation! Get in touch if you are interested or just apply. March 31st deadline. findaphd.com/phds/project/th…

The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle...

PhD Project - The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle University, listed on FindAPhD.com

findaphd.com
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New paper led by @ClarkIM1965. miRNA-455 plays a role in bone homeostasis. @mattbarter @DanJHayman thanks to the funders, especially @DunhillMedical Well done to all involved. microRNA-455 null mouse shows dysregulated bone turnover academic.oup.com/jbmrplus/ar…

The microRNA-455 null mouse shows dysregulated bone turnover

Abstract. A wide range of specific microRNAs have been shown to have either positive or negative effects on osteoblast differentiation and function, with c

academic.oup.com
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NUBI_YoungLab retweeted
Simon D. Bamforth@SimonDBamforth
8 Jan 2025
We are still taking applications for this exciting @TheBHF funded #PhDStudentship investigating the #genetics of #cardiovasculardevelopment at @UniofNewcastle. Please spread the word and share to your networks! Apply here: tinyurl.com/yc6paa5w.
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NUBI_YoungLab retweeted
Kasia Pirog@KasiaPirog1
9 Dec 2024
We are pleased to announce the 9th edition of #GeneticsMatters, our flagship public engagement event celebrating #rarediseases and rare disease research at Newcastle. Registration will open in 2025. Come see us @Discovery_Mus on the 2nd of March! @rarediseaseday @NCL_RareDisease
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NUBI_YoungLab retweeted
Sara Luzzi@luzzi_s
3 Dec 2024
Interested in RNA biology, cancer or vascular research? I have a position open for either a research assistant or a new postdoc to start expanding the fast-growing research area of cardio-oncology! Apply here: jobs.ncl.ac.uk/job/Newcastle… Happy to have informal chats! Please share 🧬.

Research Assistant/Associate - Regulation of gene expression

Research Assistant/Associate - Regulation of gene expression

jobs.ncl.ac.uk
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Delighted to see this in print. Congratulations to all involved but especially to @GrainOfScience
AJHG@AJHGNews
22 Nov 2024
Replying to @AJHGNews
📰The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk 🧑‍🤝‍🧑@grainofscience & colleagues cell.com/ajhg/fulltext/S0002…
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NUBI_YoungLab retweeted
Simon D. Bamforth@SimonDBamforth
22 Nov 2024
I have been awarded a @TheBHF 3 year #PhDStudentship so looking for enthusiastic people to apply who are interested in researching the #genetics of #cardiovascular development @UniofNewcastle with @LabPhillips and #RachelQueen. Apply here: tinyurl.com/yc6paa5w.

Search for Postgraduate Scholarships and Other Funding

Search scholarships and funding for postgraduate study at Newcastle University. Find financial support tailored to your course and eligibility.

ncl.ac.uk
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NUBI_YoungLab retweeted
Christa Maes@SCEBP_Lab
21 Oct 2024
Interested in skeletal stem/progenitor cells? Would you like to participate in this research🦴🔬🎓? We have vacancies for a postdoc (link coming soon) and a PhD student. Consider joining us @KU_Leuven @DevReg_KULeuven! More information and link to apply: kuleuven.be/personeel/jobsit…
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Our paper using systems biology to identify miR-199-5p as a regulator of chondrogenesis is out @eLife Congratulations to all involved inc. @mattbarter @soul_jamie and @ClarkIM1965 #microRNAs doi.org/10.7554/eLife.89701 Thank you again to funders @DunhillMedical @VersusArthritis

Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis

A multi-disciplined approach uncovered microRNA-199a/b-5p as important regulators of chondrogenesis, which negatively regulate mRNAs such as FZD6, ITGA3, and CAV1 for protective purposes during...

elifesciences.org
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In a week in which #microRNA discovery wins a Nobel prize, here's our new small contribution to these amazing little molecules! Great team science led by @DanJHayman doi.org/10.1016/j.bone.2024.… @CIMA_Ageing @nubiosciences @IGM_Skeletal

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Many thanks to the authors especially @FrancescaJBrito, and funders including @CIMA_Ageing @DunhillMedical
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We show how one #microRNA miR-324, which is a known serum marker for bone turnover, remarkably controls all aspects of bone homeostasis
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So pleased this manuscript is now out, well done @Climbinggirl71 @soul_jamie @mattbarter @KasiaPirog1 @4130chromo Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis mouse models journals.biologists.com/dmm/…

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Congratulations @DWilkinson_Lab SERPINA3 is a marker of cartilage differentiation and is essential for... sciencedirect.com/science/ar…

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Well done to the Gosforth Academy sixth formers who came in the lab for work experience week this year.
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Lectureship available at the University of Manchester in stem cell biology organoid biology or gene therapy The University of Manchester - Job Information | Apply for Lecturer / Senior Lecturer in the Division Cell Matrix Biology and Regenerative Medicine.
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jobs.manchester.ac.uk/Job/Jo…
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