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ICUEdandToddCast @IcuCast

Two ICU guys walk into a recording studio and talk about the latest and greatest in ICU evidence

Joined December 2022
  • Tweets 153
  • Following 271
  • Followers 1,244
12 Photos and videos
Got the post #CCRDownUnder blues? Listen to our interview and deep dive of the RSI trial with @JonathanCaseyMD, recently published in @NEJM icuedandtoddcast.buzzsprout.…

ICU Ed and Todd-Cast

Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...

icuedandtoddcast.buzzsprout.com
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We are LIVE @ Critical Care Bootcamp 2025! Thank you to conference organizers for inviting us and thank you to everyone who came out to listen! We talk about the PIC trial by Lemiale et al published in @LancetRespirMed PIC: pubmed.ncbi.nlm.nih.gov/4065… 🎧pod.link/1667336877

Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC):...

French Ministry of Health.

pubmed.ncbi.nlm.nih.gov
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Episode 72! We continue talking about CCR25 with UK-ROX and and TARGET-Protein published in @JAMA_current and presented at the #CCR25 conference UK-ROX: pubmed.ncbi.nlm.nih.gov/4050… TARGET-Protein: pubmed.ncbi.nlm.nih.gov/4049… 🎧: pod.link/1667336877

Conservative Oxygen Therapy in Mechanically Ventilated Critically Ill Adult Patients: The UK-ROX...

isrctn.org Identifier: ISRCTN13384956.

pubmed.ncbi.nlm.nih.gov
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Episode 71! We talk about FLUID published in @NEJM and BICAR-ICU from @TheLancet FLUID: pubmed.ncbi.nlm.nih.gov/4050… BICAR-ICU: pubmed.ncbi.nlm.nih.gov/2991… 🎧pod.link/1667336877

A Crossover Trial of Hospital-Wide Lactated Ringer's Solution versus Normal Saline - PubMed

A hospital-wide policy to administer lactated Ringer's solution rather than normal saline did not result in a significantly lower incidence of death or readmission to the hospital within 90 days...

pubmed.ncbi.nlm.nih.gov
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Episode 70! We have @WesElyMD join us to talk about A2B by Walsh et al published in @JAMA_current May with the @ATSBlueEditor conference. Don't miss this one! 🎧pod.link/1667336877 A2B: pubmed.ncbi.nlm.nih.gov/4038… JAMA: jamanetwork.com/journals/jam… Editorial: jamanetwork.com/journals/jam…

ICU Ed and Todd-Cast

Listen to ICU Ed and Todd-Cast wherever you get your podcasts!

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Episode 69! We talk about the articles from the #CCR25 conference with RESCUE-3 published in @ATSBlueEditor by Dres et al and PROMIZING by Bosma et al in @NEJM RESCUE-3: pubmed.ncbi.nlm.nih.gov/4049… PROMIZING: pubmed.ncbi.nlm.nih.gov/4051… Listen: pod.link/1667336877

Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-...

Although the trial was stopped early because of slow enrollment, transvenous diaphragm neurostimulation showed a high probability of potential benefit for weaning success but with a possible increase...

pubmed.ncbi.nlm.nih.gov
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Episode 68! Today we talk about modes of mechanical ventilation with the first author Dr. Kevin Seitz. This was published in @accpchest April of 2025 🎧: pod.link/1667336877 Pubmed: pubmed.ncbi.nlm.nih.gov/4018…

ICU Ed and Todd-Cast

Listen to ICU Ed and Todd-Cast wherever you get your podcasts!

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Episode 67! A simple one this time. Just a 50,000 ft overview of the presentations from the #CCR25 conference! 🎧pod.link/1667336877

ICU Ed and Todd-Cast

Listen to ICU Ed and Todd-Cast wherever you get your podcasts!

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Episode 66! We talk about Acute Chest Syndrome in Sickle Cell with one of our favorite hematologists, Benjamin Tillman! We base our discussion around the TASC trial published by Dessap et al in @ATSBlueEditor 2025. Pubmed: pubmed.ncbi.nlm.nih.gov/4020… 🎧 pod.link/1667336877

Comparison of Prophylactic and Therapeutic Doses of Anticoagulation for Acute Chest Syndrome in...

Rationale: Patients with sickle cell disease hospitalized for acute chest syndrome (ACS) are at high risk of in situ pulmonary microthrombosis. Objectives: We evaluated whether therapeutic anticoag...

pubmed.ncbi.nlm.nih.gov
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Episode 64! We talk more about steroids in severe CAP with "Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial" published in ICM in 2025. pubmed: pubmed.ncbi.nlm.nih.gov/4026…

Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The...

Clinicaltrials.gov identifier: NCT02735707 (registration date: November 4th, 2016).

pubmed.ncbi.nlm.nih.gov
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Episode 63! We talk about thrombolysis in intermediate risk PE with PEERLESS published in @CircAHA and then PEITHO from @NEJM from 2014 PEERLESS: pubmed.ncbi.nlm.nih.gov/3947… PEITHO: pubmed.ncbi.nlm.nih.gov/2471… PE Meta-analysis: pubmed.ncbi.nlm.nih.gov/2493… 🎧pod.link/1667336877

Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in the Management of...

URL: https://www.clinicaltrials.gov; Unique identifier: NCT05111613.

pubmed.ncbi.nlm.nih.gov
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Episode 62! We talk about some of the articles from the ISICEM conference and talk in depth about SESAR published in @JAMA_current with the conference last month! 🎧pod.link/1667336877 SESAR (pubmed): pubmed.ncbi.nlm.nih.gov/4009… SESAR (JAMA): jamanetwork.com/journals/jam…

ICU Ed and Todd-Cast

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Episode 61! We talk about HFNC including extubation to and how to wean it! Also, what do you think of when you think "auto-PEEP"? 🎧pod.link/1667336877 Auto-PEEP: nejm.org/doi/full/10.1056/NE… Extubate to HFNC: pubmed.ncbi.nlm.nih.gov/3987… Weaning HFNC: pubmed.ncbi.nlm.nih.gov/3992…

ICU Ed and Todd-Cast

Listen to ICU Ed and Todd-Cast wherever you get your podcasts!

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#59! We talk about TRAUMAOX2 (@JAMA_current), SAHARA (@NEJM), and answer some listener questions finishing our #ccrdownunder coverage. Great discussions! TRAUMOX2: pubmed.ncbi.nlm.nih.gov/3965… SAHARA: pubmed.ncbi.nlm.nih.gov/3965… 🎧anywhere: pod.link/1667336877

Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial -...

ClinicalTrials.gov Identifier: NCT05146700.

pubmed.ncbi.nlm.nih.gov
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#58! We talk about RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published @JAMA_current and presented #ccrdownunder. We pair with FLORALI! 🎧anywhere: pod.link/1667336877 JAMA: jamanetwork.com/journals/jam…

ICU Ed and Todd-Cast

Listen to ICU Ed and Todd-Cast wherever you get your podcasts!

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Episode 57! We were excited to have @adamatw PhD in Bioinformatics to discuss SCREEN published by Arabi et al in JAMA 2024 and presented at #CCRDownUnder. A long episode but a lot of good discussion SCREEN: pubmed.ncbi.nlm.nih.gov/3965… Listen anywhere: pod.link/1667336877
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#56! We talk about ADAPT-Sepsis or "Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis" published in @JAMA_current and presented at #ccrdownunder 🎧anywhere: pod.link/1667336877 Pubmed: pubmed.ncbi.nlm.nih.gov/3965… JAMA: jamanetwork.com/journals/jam…

ICU Ed and Todd-Cast

Listen to ICU Ed and Todd-Cast wherever you get your podcasts!

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2024 year-in-review and overview of #ccrdownunder! TIGHT K: pubmed.ncbi.nlm.nih.gov/3921… PROPHY VAP: pubmed.ncbi.nlm.nih.gov/3826… REVISE: pubmed.ncbi.nlm.nih.gov/3887… Withdrawal ECMO: pubmed.ncbi.nlm.nih.gov/3966… DanGer SHOCK: pubmed.ncbi.nlm.nih.gov/3858… Intubation guidelines: pubmed.ncbi.nlm.nih.gov/3916…

Potassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery: The TIGHT K...

ClinicalTrials.gov Identifier: NCT04053816.

pubmed.ncbi.nlm.nih.gov
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Episode 54! In this episode we talk about antibiotic duration in bacteremia (BALANCE) and also antibiotic duration in Pseudomonas VAP (iDIAPASON).  BALANCE: pubmed.ncbi.nlm.nih.gov/3956… iDIAPASON: pubmed.ncbi.nlm.nih.gov/3555… Listen anywhere: pod.link/1667336877

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections - PubMed

Among hospitalized patients with bloodstream infection, antibiotic treatment for 7 days was noninferior to treatment for 14 days. (Funded by the Canadian Institutes of Health Research and others;...

pubmed.ncbi.nlm.nih.gov
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Episode 53! A shorter episode but a good one where we talk about IV vs IO access in cardiac arrest with two articles published in @NEJM. Also, great acronyms! IVIO: pubmed.ncbi.nlm.nih.gov/3948… PARAMEDIC-3: pubmed.ncbi.nlm.nih.gov/3948… Listen anywhere: pod.link/1667336877

Intraosseous or Intravenous Vascular Access for Out-of-Hospital Cardiac Arrest - PubMed

There was no significant difference in sustained return of spontaneous circulation between initial intraosseous and intravenous vascular access in adults who had out-of-hospital cardiac arrest....

pubmed.ncbi.nlm.nih.gov
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