Single Cell Gescheft @WeizmannScience

Joined November 2017
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What if we could turn the tumorโ€™s deadliest tricks against it? New @Cancer_Cell: Tumor-antigen-independent targeting of solid tumors by armored macrophage-directed anti-TREM2 CAR T cells. Led by @GalYagel, @D_Rimini & @MVLocquenghien (1/15) cell.com/cancer-cell/abstracโ€ฆ
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If you want to do great and creative science with the most AMAZING PI, this is the place to go!! ๐Ÿ”ฅ๐Ÿคฉ
hello world. Excited to launch the Ingelfinger Lab account! Weโ€™re a young lab in Germanyโ€™s Black Forest tackling key questions in immunology with innovative single-cell technologies. Follow us for updates on systems immunology, machine learning & translational oncology. fi
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๐ŸŽ„Christmas came early this year!๐ŸŽ„ We have an additional 50 places available at this year's #SCG2026 taking place from September 16th-18th in beautiful Dunblane, Scotland Full details and registration link ๐Ÿ‘‡๐Ÿผ conferences.weizmann.ac.il/Sโ€ฆ Abstract deadline is in two weeks (June 15th)

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Celebrating Shavuot with our annual lab cooking competition! This yearโ€™s dishes made the competition especially tough, with creativity and flavor at every table. Wishing our friends around the world a joyful holiday!
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Absolute joy hosting the one and only @jonykipnis to discuss the frontiers of neuroimmunology and how we can translate these discoveries into next-generation immunotherapies.
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Come join us for this stimulating talk! @jonykipnis
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Beautiful work Marco and co. congratulations!
What defines human pDC diversity? Our newest work led by @UlezkoAlina in @ImmunityCP uncovers a complex landscape shaped by age and tissue niche, including a cycling pDC subset that declines with age but persists in the BM & expands in malignant BPDCN. shorturl.at/99Zui
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Fantastic new study by @Brown_lab1, @MiriamMerad and teams: mRNA vaccine potency comes from detargeting hepatocytes, not dendritic cell expression, avoiding PD1/PDL1-driven T cell suppression. A path to better, more effective therapies. nature.com/articles/s41587-0โ€ฆ
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ืขื™ื“ืŸ ื—ื“ืฉ ื‘ืืžืช. ื”ืžื—ืงืจ ื”ื–ื” ื”ื•ื ื”ื™ืฉื’ ื’ื“ื•ืœ ืœื”ื“ืกื” ื•ืœืจืคื•ืื” ื”ื™ืฉืจืืœื™ืช, ื•ืžืฆื™ื‘ ืืช ื™ืฉืจืืœ ื‘ื—ื–ื™ืช ื”ืขื•ืœืžื™ืช ืฉืœ ื˜ื™ืคื•ืœื™ CAR-T ืœืžื—ืœื•ืช ืื•ื˜ื•ืื™ืžื•ื ื™ื•ืช. ืฉืืคื• ื’ื“ื•ืœ ืœืคืจื•ืคโ€™ ื—ืžื•ื˜ืœ ื’ื•ืจ, ืคืจื•ืคโ€™ ืคื•ืœื™ื ื” ืกื˜ืคื ืกืงื™ ื•ื“โ€ืจ ืฉืœืžื” ืืœื™ืืก ืขืœ ื”ื•ื‘ืœื” ืืžื™ืฆื” ื•ื—ื“ืฉื ื™ืช ืฉืœ ืชื—ื•ื ืขื ืคื•ื˜ื ืฆื™ืืœ ืœืฉื ื•ืช ืืช ื—ื™ื™ ื”ืžื˜ื•ืคืœื™ื ืžืŸ ื”ื™ืกื•ื“.
ื˜ื™ืคื•ืœ ื‘ืžื—ืœื•ืช ืื•ื˜ื•ืื™ืžื•ื ื™ื•ืช ื‘ืืžืฆืขื•ืช car. ื›ื™ื•ืŸ ืฉืจื‘ื™ื ืคื•ื ื™ื ื ื‘ื”ื™ืจ: ืื ื—ื ื• ื‘ื”ื—ืœื˜ ืžื˜ืคืœื™ื ื‘ CAR-T ื‘ื—ื•ืœื™ื ืขื ืžื—ืœื•ืช ืื•ื˜ื•ืืžื•ื ื™ื•ืช. ื ื›ื•ืŸ, ื–ื” ื‘ืฉืœื‘ ืืงืกืคืจื™ืžื ื˜ืœื™ ืื‘ืœ ื˜ืคืœื ื• ื›ื‘ืจ ื‘ืžืขืœ 10 ื—ื•ืœื™ื ืขื ืชื•ืฆืื•ืช ืžืฆื•ื™ื ื•ืช ! ื™ืฉ ืœื‘ื—ื•ืจ ื˜ื•ื‘ ืืช ื”ืžืชืื™ืžื™ื ืื‘ืœ ื”ื˜ื™ืคื•ืœ ื”ื•ื›ื— ื›ื‘ืจ ื›ื™ืขื™ืœ (ืืฆืœื ื• ื•ื‘ืื™ืจื•ืคื”) ื‘ื˜ื•ื•ื— ืฉืœ ืฉื ืชื™ื™ื ืฉืœื•ืฉ (ืขื“ ื›ื”) ื‘ืœื•ืคื•ืก, ืžื™ื•ื–ื™ื˜ื™ืก, ืกืงืœืจื•ื“ืจืžื”, apla, ื•ืขื•ื“. ืขื™ื“ืŸ ื—ื“ืฉ. ื”ื˜ื™ืคื•ืœ ื‘ืœื ืžืขื˜ ืžืงืจื™ื ื’ื•ืจื ืœ resetting ืฉืœ ื”ืžืขืจื›ืช ื”ืื™ืžื•ื ื™ืช, ื•ื›ืืŸ ืชืงื•ื•ืชื ื• ืœืจื™ืคื•ื™! ื•ืœื ืจืง ื”ืคื•ื’ื” ื‘ืœืคื—ื•ืช ื—ืœืง ืžื”ื—ื•ืœื™ื. ืขื™ื“ืŸ ื—ื“ืฉ. ืื‘ืœ ื™ืฉ ืœื‘ืจื•ืจ ืืช ื”ืžื˜ื•ืคืœื™ื ื”ืžืชืื™ืžื™ื.
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#SCG2026 registration opens at 1 PM UK time on Thursday, 30 April. Spots are limited, and in previous years registration filled in less time than it takes to run a UMAP. Register here: conferences.weizmann.ac.il/Sโ€ฆ
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Congratulations Dr. Von Locquenghien @MVLocquenghien for successfully defending your PhD thesis! ๐ŸŽ‰
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Mimouna celebration at the AmitLab! ๐Ÿคฉ๐ŸŽ‰
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This is what real progress against cancer looks like: immunotherapy exploiting tumor vulnerabilities one after another. Now itโ€™s time to extend that progress to many more tumor types!
How outcomes in relapsed/refractory multiple myeloma changed, from 1986 to 2026
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Celebrating amazing discoveries, innovation, and the people who make it all possible. #Unstoppable
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Beautiful and important work from Aaron, colleagues, and the Adimab team. If we are still missing such a basic property of therapeutic antibodies, imagine how much of Ab mechanism of action we still do not fully understand, and how much more could be achieved if we did.
How specific are therapeutic monoclonal antibodies, really? In our new paper, @Yile_Dai led a collaboration with Adimab to profile 174 FDA-approved and clinical-stage mAbs against 6,172 human extracellular proteins. What we found surprised us.๐Ÿงต sciencedirect.com/science/arโ€ฆ
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Thank you @CancerCell for featuring our cover! ๐Ÿ Inspired by honeybee โ€œsocial immunityโ€ where colonies detect and manage sick nestmates, we engineered TME-regulated armored TREM2 CAR T cells to unmask and dismantle immunosuppressive niches in solid tumors @GalYagel @D_Rimini
Dive into our March issue, out now: cell.com/cancer-cell/issue?pโ€ฆ
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Thank you @lai9uan and @FGinhoux for highlighting our reaserch! Congratulations for the new Vita journal and team!
Our commentary in #Vita journal with @FGinhoux highlights an elegant study from the @IdoAmitLab @CellCellPress , a clever design for immunocytokines that selectively activate within tumors - linking myeloid reprogramming to trigger maximum response. Link: shorturl.at/GXPJO
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Fantastic meeting and lineup, looking forward!
Join us at Cell Symposia: Single-Cell Biology in the Era of AI (Dec 2โ€“4, 2026, Munich) ๐Ÿ‡ฉ๐Ÿ‡ช From multi-omics to AI-driven models of cellular dynamics โ€” an exciting lineup across experimental & computational biology. Hope to see you there! ๐Ÿ”— cell-symposia.com/single-celโ€ฆ
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