Joined December 2024
- Tweets 19
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- Followers 49
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Pinned Tweet
6 Dec 2024
Excited to share the lab's first preprint ! We previously observed CD226 macrophages in brown fat that resemble CCR2- and IRF4-dependent peritoneal small Macs, but we didn't know anything about them...
biorxiv.org/content/10.1101/…
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Jan 7
Happy to see this paper out @NatImmunol !
To read it : rdcu.be/eX0JB
Great collaboration with the Becher lab @UZH_en. @AlexGallerand @LP2M_Lab @Univ_CotedAzur @CNRS_DR20
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Jan 7
This novel macrophage population in salivary glands is regulated by ILC-2 derived GM-CSF and arises mostly from MDP-derived monocytes. Importantly, they also express CD226 and have a lot in common with the population we describe in adipose tissue... More to come !
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22 Jul 2025
CSF1R regulates monocyte subset differentiation and intracellular metabolism. biorxiv.org/content/10.1101/…
Our new preprint is now online ! Here, we explore links between CSF1R signalling, intracellular metabolism and monocyte differentiation.@LP2M_Lab @Cnrs20 @Univ_CotedAzur @Inserm
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22 Jul 2025
We report that surface CSF1R expression relies on continuous translation and export to the membrane. CSF1R recycling rate accelerates as monocytes differentiate from the Ly6Chigh to the Ly6Clow subset, and CSF1R blockade prevents Ly6Chigh commitment towards this trajectory.
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22 Jul 2025
CSF1R signalling sustains glucose uptake in Ly6Chigh monocytes to fuel the hexosamine biosynthetic pathway (HBP), which in turn allows optimal CSF1R expression. Impairing glucose flux towards HBP through GFPT1 invalidation leads to increased Ly6Chigh/Ly6Clow ratio.
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23 Jun 2025
nature.com/articles/s42003-0…
A great work by the Williams lab! Thank you for the collaboration. More to come :) @Lab__Williams @LP2M_Lab @CNRSbiologie @Cnrs20 @Inserm @Univ_CotedAzur
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4 Jun 2025
Congrats @LettieriBarbato and team for their recent publication on brown adipose tissue macrophages, happy to have been involved in the project !
@LP2M_Lab @CNRSbiologie @Univ_CotedAzur @Lab__Williams
nature.com/articles/s41467-0…
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Ivanov lab retweeted
6 Dec 2024
Excited to share the lab's first preprint ! We previously observed CD226 macrophages in brown fat that resemble CCR2- and IRF4-dependent peritoneal small Macs, but we didn't know anything about them...
biorxiv.org/content/10.1101/…
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15 Jan 2025
Happy to see this study published in @HEP_Journal, resulting from a great collaboration with Philippe Gual @C3M_U1065 @LP2M_Lab @CNRS_DR20 @Inserm @Univ_CotedAzur with contribution from @Lab__Williams @AlexGallerand @Bastien_Dolfi
journals.lww.com/hep/abstrac…
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6 Dec 2024
Excited to share the lab's first preprint ! We previously observed CD226 macrophages in brown fat that resemble CCR2- and IRF4-dependent peritoneal small Macs, but we didn't know anything about them...
biorxiv.org/content/10.1101/…
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6 Dec 2024
We report that this subset is conserved across several tissues and especially fat, in which they regulate lipid metabolism. Importantly, these cells have a rapid turnover from monocytes, and in particular MDP-derived monocytes that are biased to differentiate into CD226 Macs !
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6 Dec 2024
Thanks to team members and key collaborators @AlexGallerand @adeline_bertola @maxim_artyomov @Bastien_Dolfi @DavidMASSON14 @FGinhoux @lab_mass @Lab__Williams and all other people involved !
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Ivanov lab retweeted
6 Dec 2024
Happy to see our review on macrophages of the vascular system published in Nature Cardiovascular Research !
@GwenRandolph_ @jichang_han @IvanovLab nature.com/articles/s44161-0…
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Ivanov lab retweeted
27 Sep 2024
🚨preprint alert! Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages (LAMs)
biorxiv.org/content/10.1101/…
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Ivanov lab retweeted
19 Oct 2024
Ivanov lab paper ! Very happy to see our story on monocyte glucose metabolism online in @NatureComms today. Inhibition of Glut1 depletes the majority of blood monocytes, yet atherosclerotic plaques still develop normally🧐 @LP2M_Lab
nature.com/articles/s41467-0…
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Ivanov lab retweeted
28 May 2024
Happy to see this story out!
@LP2M_Lab @Univ_CotedAzur @CNRS_DR20 @Bastien_Dolfi @AlexGallerand
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes - Dolfi - European Journal of Immunology - Wiley Online Library onlinelibrary.wiley.com/doi/…
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Ivanov lab retweeted
15 Jun 2022
Glad to share our new study investigating the unknown diversity of adrenal glands macrophages. I would like to thanks all my team and collaborators for this incredible work ! cell.com/cell-reports/fullte…
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Ivanov lab retweeted
6 Sep 2021
Out in Nat Comms! nature.com/articles/s41467-0…
Great work by @AlexGallerand, @MarionAlya, Stoyan and many others.
This one is very special, and I wanted to highlight all the amazing single-cell analysis done by @mfiruleva, allowing me to do more as a senior author for the first time
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