Lab of Dr. Jonathan P. Jacobs | #UCLAGI@dgsomucla | Translational approach to study the role of the intestinal microbiome in human disease | Microbiome Core
Excited to share our new work in @ISMEJournal exploring the biogeography of the gut microbiome in SPF and germ-free mice colonized with mouse or human feces (a common tool for inferring microbiome causality).
academic.oup.com/ismej/advan…
Many thanks also to the UCLA Microbiome Core, Goodman-Luskin Microbiome Center, UCLA Technology Center for Genomics & Bioinformatics, and the National Gnotobiotic Rodent Resource Center at UNC! Proud to be @UCLAGIHep@dgsomucla !
#GUTImage from the paper by Jacobs et al entitled
"Age-related patterns of microbial dysbiosis in multiplex inflammatory bowel disease families" via
bit.ly/4flRHcp#IBD
Dr. Jesús A. Araujo & @JacobsLabUCLA 🔖in @IJMS_MDPI - Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6 Trinitrobenzenesulfonic Acid
👉 mdpi.com/1422-0067/25/13/718…
Dr. Jesús Araujo and Dr. Jonathan Jacobs’ new study investigates air pollution’s impact on colitis and cardiovascular health. While pollution doesn’t exacerbate colitis in their models, it may influence cardiovascular risk through gut bacteria. Read more: uclahs.fyi/4g7KugR
Microbiota-Dependent Upregulation of Bitter Taste Receptor Subtypes in the Mouse Large Intestine in High-Fat Diet-Induced Obesity 🔖@Nutrients_MDPI
🖊️F Caremoli J Huynh V Lagishetty D Markovic Jonathan Braun @TienDongMD@JacobsLabUCLA Catia Sternini
👉mdpi.com/2072-6643/15/19/414…
👏Dr. David Meriwether @NIH K01 grant: Dysregulation of inflammation resolution as therapeutic target for #IBD
🎯Investigating molecular mechanisms by which pro-inflammatory macrophages transition to inflammation-resolving phenotype following phagocytosis of apoptotic cells.