@JaeschkeLab profile picture
Jaeschke Lab @JaeschkeLab

Our group at @IPMB_HD explores unknown roles of RNA modifications, new methods for live cell RNA imaging, photoswitchable biomolecules and the origin of life.

Joined July 2020
  • Tweets 117
  • Following 218
  • Followers 626
11 Photos and videos
🚨 PhD Opportunity in Epitranscriptomics! 🚨 The Jäschke Lab at @UniHeidelberg is offering a PhD position for an ERC-funded project on coenzyme-linked RNAs. Join us in uncovering novel RNA modifications & their biological roles! 🔬 #Biochemistry, #RNA jaschkelab.de/join

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jaschkelab.de
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Jaeschke Lab retweeted
Michael Smietana@Smietana_M
16 Apr 2024
📢New PhD position available in our lab in collaboration with @JaeschkeLab developing new RNA modifications. We are looking for an organic chemist with an interest in life sciences. To apply : tinyurl.com/54fmm8bj @enscmchimiemtp @umontpellier @IBMM_Balard @ChemBioNAC PLS RT
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Our research group at @IPMB_HD in @UniHeidelberg is offering a new @dfg_public -funded #PhD position to investigate one of the greatest mysteries in modern science: the origin of #Life and the #Genetic code! More info at: jaschkelab.de/join Please RT!

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jaschkelab.de
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We are very excited to share our new preprint about protein high- and super-resolution #imaging with bifunctional #aptamers! biorxiv.org/content/10.1101/…

Super-resolved protein imaging using bifunctional light-up aptamers

Efficient labeling methods for protein visualization with minimal tag size and appropriate photophysical properties are required for single-molecule localization microscopy (SMLM), providing insights...

biorxiv.org
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Jaeschke Lab retweeted
Murat Sunbul@MuratSunbul_Lab
19 Jan 2024
📢Please RT📢 I'm looking for PhD and PostDoc fellows interested in #ChemicalBiology, #RNA interactomes, #Fluorophores, super-resolution #Imaging & new technologies for Spatial Biology @UniHeidelberg @IPMB_HD in my group. #ERC funded Please apply! Info: sunbulgroup.com
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Angewandte Chemie@angew_chem
8 Dec 2023
Photochromic Nucleosides and Oligonucleotides (Andres Jaeschke and co-workers) @JaeschkeLab #OpenAccess thanks to #ProjektDEAL onlinelibrary.wiley.com/doi/…

Photochromic Nucleosides and Oligonucleotides

The incorporation of photoswitchable moieties into biological macromolecules has emerged as a promising approach to manipulate and study complex processes in living organisms. In this review, we...

onlinelibrary.wiley.com
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Jaeschke Lab retweeted
Murat Sunbul@MuratSunbul_Lab
23 Nov 2023
I am extremely excited and honored to receive #ERCCoG to investigate complex interaction networks of disease-related RNAs @UniHeidelberg @IPMB_HD Many thanks to @ERC_Research, my family, team, colleagues and mentors for their support.
European Research Council (ERC)
@ERC_Research
23 Nov 2023
📢 Results of the 2023 ERC Consolidator Grant competition are out. €627 million for 308 researchers. Who has been offered funding? What topics and questions will they investigate? Where will they conduct their research? 🇪🇺@HorizonEU #ERCCoG news 👉 europa.eu/!qvtkcH
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2023 has been a great year for @JaeschkeLab alumni! First @HoeferLab obtained an @ERC_Research Starting Grant and now also @Murat__Sunbul! Many congratulations to both 👏🏻
Jaeschke Lab@JaeschkeLab
23 Nov 2023
Many congratulations to @Murat__Sunbul for being awarded an @ERC_Research Consolidation Grant!
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Many congratulations to @Murat__Sunbul for being awarded an @ERC_Research Consolidation Grant!
European Research Council (ERC)
@ERC_Research
23 Nov 2023
📢 Results of the 2023 ERC Consolidator Grant competition are out. €627 million for 308 researchers. Who has been offered funding? What topics and questions will they investigate? Where will they conduct their research? 🇪🇺@HorizonEU #ERCCoG news 👉 europa.eu/!qvtkcH
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Are you a motivated scientist with a strong background in mass #spectrometry? Our group at @UniHeidelberg is offering a #postdoc position (funded by an @ERC_Research grant) for the study of new #epitranscriptomic #RNA modifications. More info at: jaschkelab.de/join Please RT

Join

jaschkelab.de
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Are you a motivated young scientist with a strong interest in #RNA biochemistry? Our research group at @UniHeidelberg is offering a new #PhD position (fully funded by an @ERC_Research grant) in the field of #epitranscriptomics! More info at: jaschkelab.de/join Please RT!
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We are very excited to announce that our new review about the future perspectives for the identification and #sequencing of Nicotinamide Adenine Dinucleotide (NAD)-capped #RNAs has just been published in @ACSPublications! pubs.acs.org/doi/10.1021/acs…

Future Perspectives for the Identification and Sequencing of Nicotinamide Adenine Dinucleotide-Ca...

ConspectusRibonucleic acid (RNA) is composed primarily of four canonical building blocks. In addition, more than 170 modifications contribute to its stability and function. Metabolites like nicotin...

pubs.acs.org
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We are at @embl participating in the Seeing is Believing symposium! Comefind Franziska Grün at Poster No. 97 or Simon Fürbacher at Poster No. 89. #EESImaging #embl #imaging #science #RNA
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Check out our new manuscript where we describe efficient synthesis and in vitro enzymatic processic of UDP-GlcNAc-RNA! Now on Biorxiv! biorxiv.org/content/10.1101/…

Identification and in vitro characterization of UDP-GlcNAc-RNA cap-modifying and decapping enzymes

In recent years, several noncanonical RNA caps derived from cofactors and metabolites have been identified. Purine-containing RNA caps have been extensively studied, with multiple decapping enzymes...

biorxiv.org
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Jaeschke Lab retweeted
Murat Sunbul@MuratSunbul_Lab
17 Aug 2023
Amazing discovery that will lead to a new chapter in biochemistry textbooks. #RNA-#Protein conjugates in bacteria 🙀 Congratulations to @MaikSchauerte @HoeferLab @JaeschkeLab
Jaeschke Lab@JaeschkeLab
16 Aug 2023
We are very excited to announce that our new paper has been published in @Nature! Meet the new ‘RNAylation’ reaction: a viral ADP-ribosyltransferase (ART) is able to attach #RNA chains to E. coli proteins! Congratulations @JaeschkeLab @HoeferLab UrlaubLab nature.com/articles/s41586-0…
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Jaeschke Lab retweeted
Olivier Duss@OlivierDuss
17 Aug 2023
RNA covalently links to proteins: today in @Nature! #RNAylation as new post-translational modification (or #Proteinylation as new post-transcriptional RNA modification!) by @HoeferLab, @JaeschkeLab, @MaikSchauerte. Important during #phage infection! nature.com/articles/s41586-0…

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Maik Wolfram-Schauerte@MaikSchauerte
16 Aug 2023
Excited about our publication in @Nature, unveiling an innovative process: RNAylation leading to novel #protein-#RNA conjugates. Grateful for contributions and support from @HoeferLab, @JaeschkeLab, and Urlaub Lab!
kathaRiNA Höfer@HoeferLab
16 Aug 2023
Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
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Jaeschke Lab retweeted
Nadiia Pozhydaieva@pozhydaievan
16 Aug 2023
A decisive response to those who find t4 phage boring and believe there's nothing left to explore! Check out this great paper that will prove you wrong! Congrats to the first author @MaikSchauerte! 🙌 Proud to have contributed to such an amazing project! 🤩 @HoeferLab 💪🏽
kathaRiNA Höfer@HoeferLab
16 Aug 2023
Did you know that bacterial #viruses glue #RNA to proteins? We discovered that a T4 #phage #ART links NAD-RNA to E. coli proteins. We call this an #RNAylation. Great collaboration with @JaeschkeLab and Urlaub Lab. Congratulations to @MaikSchauerte 🍾 nature.com/articles/s41586-0…
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Jaeschke Lab retweeted
Maik Wolfram-Schauerte@MaikSchauerte
16 Aug 2023
Very happy to see our paper about the #RNAylation out in @Nature! This demonstrates that #phage research can still enable exciting and novel discoveries! Special thanks to @HoeferLab, as well as @JaeschkeLab and UrlaubLab for contributions and support!
Max Planck Institute for Terrestrial Microbiology@mpi_marburg
16 Aug 2023
Paper Alert 🚀 Research by @MaikSchauerte @HoeferLab on #Bacteriophages reveals new principle of RNA-protein binding. #RNAylation - an exciting discovery for #phagetherapy, #SynBio & #drug development. @SYNMIKRO @UniHeidelberg mpi-marburg.mpg.de/1312595/2…
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Paper Alert 🚀 Research by @MaikSchauerte @HoeferLab on #Bacteriophages reveals new principle of RNA-protein binding. #RNAylation - an exciting discovery for #phagetherapy, #SynBio & #drug development. @SYNMIKRO @UniHeidelberg mpi-marburg.mpg.de/1312595/2…

Viruses glue RNA to proteins

Until now, RNAs and proteins were thought to interact only briefly during cellular processes. Researchers at the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, have discovered...

mpi-marburg.mpg.de
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