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BREAKING: FIRST PUBLICATION NOW AVAILABLE β>
doi.org/10.1016/j.metabol.20β¦
KETO-CTA (
#LMHRstudy) vs Control (
#MiHeart)
-πPlease Share! π-
METHODS βΒ 80 Participants of
#LMHRstudy fell within
#MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the
#MiHeart cohort.
PRIMARY ANALYSIS βΒ High resolution heart scans (
#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)
RESULTS
The matched mean age was 55.5 years, with mean
#LDL cholesterol of 272 mg/dL (max LDL-C 591) mg/dl and mean 4.7 years duration on a ketogenic diet.
π¨ There was no significant difference in coronary plaque burden of
#LMHRstudy (mean LDL-C 272) cohort as compared to
#MiHeart controls (mean LDL 123 mg/dl); nb: pre-KETO LDL-C in KETO group was 122 mg/dl
π¨ There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520
π¨ No relationship of LDL-C elevations and plaque
β οΈ NOTE: This analysis is on baseline scans, we will have further data on the Keto-CTA longitudinal analysis in the coming months. And β as always β please continue to work with your doctor.
πππ Special thanks to everyone who got us to this first publication milestone. πππ
Extra shout out to
@nicknorwitz @DrRagnar @AdrianSotoMota @khurramn1 and, ofc,
@BudoffMd
And a MASSIVE thanks to everyone who has contributed their money, time, and/or sharing to help us spread the word and make this research a reality!
(PS β this is unfortunately not Open Access as this wasnβt an option we had available for us β but the full manuscript will be published soon as a separate paper and *will* be open access)