Assistant Prof of Human Genetics @UChicago. Working at the intersection of population, statistical and quantitative genetics. tweets my own. he/him/his
We are hosting the 2026 edition of the Midwest Population Genetics Meeting at UChicago on August 21 and 22! This is a trainee focused meeting with many opportunities to present!
I am looking for a postdoc to work in theoretical population genetics. We focus on theory and methods for inferring demographic histories and selection using modern and ancient genomic data. Come join our amazing community in Chicago. More info here: steinrueckenlab.uchicago.edu…
I'm thrilled to announce that I've joined the Section of Genetic Medicine at the University of Chicago as an assistant professor! The Simons lab is officially open!
yuvalsimons.org/
This isn't a new thought, but I'm wondering today how much of the pervasive sense of burnout or disengagement among life science professors today is a sense of soft institutional betrayal for the last three years. That our institutions do not share our morals
Our approach is simple to implement and can provide better protection against confounding than the standard PCA approach when the test of interest is known ahead of time
We then show how to correct for this bias when testing for the association between PGSs and an ancestry gradient of interest in the prediction panel by leveraging the overlap in structure between the two panels
Motivated by recent evidence of residual confounding in PGS, we first use a simple model of genetic relatedness to show how confounding in the GWAS biases the distribution of PGS in the prediction panel in a way that depended on the overlap in population structure between panels
If anyone knows of any data science / pop gen positions in industry please get in touch! NYC area or remote.
@Color laid off ~50% of the company. Genomics R&D work basically out. Frustrating news, but proud of my contributions and grateful for all I learned & great colleagues.
Thrilled to share that our manuscript on T2D genetic clustering is now published!
Soft clustering analysis of type 2 diabetes loci identifies ten physiologically interpretable genetic clusters associated with distinct tissues and clinical outcomes.
link.springer.com/article/10…
super excited to share our new paper on polygenic epistasis! we introduce a new model and show how structured statistical epistasis can help us study complex trait biology. huge thanks to my friend and lab-mate @studyjeromics, and my mentor @andywdahl!
biorxiv.org/content/10.1101/…
At the same time, I saw more clumsy talk about human genetic and phenotypic diversity than I usually see at ASHG. Clumsy ~= categorical, simplistic, mixing environment and genetics without clarity, omitting of crucial caveats, and using outdated or loaded language.
It was great to see so many friends at #ASHG22. There was also plenty of exciting research. At the same time, I left the conference with some concerns (thread)
I'm recruiting PhD students and postdocs to join my group @MPI_EVA_Leipzig in 2023! If you are interested in primate functional genomics, cell culture systems, and/or complex skeletal traits, please apply!
📢📢 Join our vibrant research community @MPI_EVA_Leipzig! We're offering PhD and/or postdoc positions in areas incl. primate behavior & evolution; human adaptation, ecology & culture; human evolutionary genomics. Check it out & apply by 1st December 2022! eva.mpg.de/career/positions-…