Assistant professor in quantitative and computational biology @USC. Genetics, evolution, and a bit of statistics.
Joined November 2015
- Tweets 3,259
- Following 2,771
- Followers 4,350
- Likes 14,301
241 Photos and videos
Doc Edge retweeted
17 Oct 2025
Happy to announce our paper on a new genotyping algorithm, ctyper. nature.com/articles/s41588-0… . This is amazing work by Walfred Ma, someone you will want to keep on your radar for future contributions to science.
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Doc Edge retweeted
18 Sep 2025
Murray and most of race twitter has apparently been fooled by this completely fabricated analysis purporting to show African ancestry is associated with IQ. People lie on twitter all the time, but this is both more revealing and more disturbing than usual. A 🧵
16 Sep 2025
Proposition: Everything that has been learned about the nature of the B/W difference in the subsequent 56 years of research is consistent with Jensen’s expectations in 1969. I stand ready to be corrected.
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Doc Edge retweeted
16 Aug 2025
Another genetic genealogy case from the US where the FBI used the MyHeritage DNA database without the consent of their users. The prosecution are also refusing to provide discovery of the relevant information. masslive.com/news/2025/08/fb…
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Doc Edge retweeted
15 Aug 2025
Scientific tragedy
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📣Online NOW!
📄Estimation of demography and mutation rates from one million haploid genomes
🧑🤝🧑 @jgschraiber @DocEdge85 & co
cell.com/ajhg/abstract/S0002…
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Doc Edge retweeted
2 Aug 2025
This is a really good lay article on embryo selection but IMO is overly credulous of risk reductions that emerge as a consequence of statistical assumptions rather than actual disease etiology. The disease model *really* matters ...
31 Jul 2025
Here's our magazine article (w/ @ToddLencz):
aeon.co/essays/embryo-risk-s…
It's not paywalled, language as accessible as possible, very balanced based on the latest research as of writing.
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Doc Edge retweeted
30 Jul 2025
People still think "Gattaca" is just a fairy tale, because a eugenic dystopia must be something imposed on us rather than something we all voluntarily choose.
30 Jul 2025
The latest embryo selection company is live, and guess what:
They're publicly letting people select for IQ!
If you want to see what they can do for your family for a variety of traits, go check out their website where they've got a calculator app available.
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Doc Edge retweeted
25 Jul 2025
I'm thrilled that my lab at NYU is now supported by an NIH MIRA grant! I'm looking to hire 1-2 senior lab members (outstanding postdoc candidates or experienced staff scientists) with expertise in computational and statistical methods in human genetics or genomics. Please share!
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Very happy to share our new paper now on @medrxivpreprint: “Genetic risk effects act in sets”, a great effort led my PhD student @JolienRietkerk, and performed together with collaborators @andywdahl, @AndrewSchork, @jonathan_flint1 etc. Thread 1/n
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Doc Edge retweeted
16 Jul 2025
New preprint with Guy Sella on the question: what is polygenicity?
biorxiv.org/content/10.1101/…
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15 Jul 2025
One of my favorite categories of thing is "guy decides to spend decades on an insane, idiosyncratic, solo art project of staggering scope". Other entries include the Watts Towers, Coral Castle, Forestiere Underground Gardens, Le Palais Ideal
15 Jul 2025
this guy spent 21 years building a miniature version of nyc consisting of almost a million buildings, the full model is 50 feet long and 30 feet wide, and he first announced it on tiktok like this:
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Doc Edge retweeted
3 Jun 2025
latest paper from the lab led by PhD student Gilia Patterson. Gilia has developed a spatially explicit deep learning method for close kin mark recapture that we think will be extremely useful for conservation biology biorxiv.org/content/10.1101/…
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Doc Edge retweeted
19 May 2025
Mutation-selection-drift balance models of complex diseases biorxiv.org/content/10.1101/… #biorxiv_genetic
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Doc Edge retweeted
17 May 2025
When should adaptation arise from a polygenic response versus few large effect changes? biorxiv.org/content/10.1101/… #biorxiv_evobio
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Doc Edge retweeted
17 May 2025
I went on WBUR today to talk about the grant terminations and the importance of basic medical research
wbur.org/news/2025/05/16/har…
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Doc Edge retweeted
15 May 2025
In the right conditions, antibiotic resistance can happen extremely fast. Here is an example from my own work of bacteria overcoming an antibiotic in just eleven days in a giant petri dish:
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Doc Edge retweeted
15 May 2025
This entire line of research, after being repeatedly selected in rigorous open national competitions for funding, was cut this week as collective political retribution x.com/baym/status/1922435976…
13 May 2025
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
ALT A screenshot showing "Outstanding Investigator Grants"
ALT A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted
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Doc Edge retweeted
11 May 2025
Hanania advocated passionately against "race mixing" for years, so he knows what he's talking about here. But it's worth adding that race-IQ obsessives also tend to make very poor predictions about the future. Let's review ...
9 May 2025
I explain the intoxicating effect on some people of thinking about race differences in IQ and how it leads people to go crazy. Stay off drugs.
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Doc Edge retweeted
29 Apr 2025
In population #GENETICS, Q-ST and F-ST calculations help compare the amount of trait differentiation on one or more traits in genome-wide genetic variants. Using simulations Liu and @DocEdge85, show the effect of various choices made while computing Q-ST.
buff.ly/313bkfU
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Doc Edge retweeted
28 Apr 2025
In a new #GENETICS research, @Dandan_Peng, Mulder, and @DocEdge85 evaluate the performance of several ancestral recombination graph (ARG) estimation methods used for determining the historical time course of a population-mean polygenic score.
Read more: buff.ly/Xr9nFjB
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