CEO at @InnBioresearch, the og project that created #DeSci to disrupt pharma. Research scientist, #blockchain dev, #game dev, #AI dev. Oh, and I love #JDM cars.

Joined January 2010
629 Photos and videos
Pinned Tweet
Glad to have been featured by the official @Nissanitalia account as representing the Italian #JDM #Nissan #SkylineGTR community. The Nissan Skyline R33 GTR has always been my dream car #godzilla $INNBC
C'è chi legge storie di leggende e chi le vive. Proprio come il nostro Jonathan con la sua mitica #Nissan #GTR. 📷: Jonathan Fior
3
6,017
Jonathan Fior🇮🇹 retweeted
Replying to @BioProtocol
What if the true pioneers of Decentralized Science didn't care about the latest marketing trends or launching speculative tokens, but about saving lives? While you follow hype-driven narratives like longevity to maximize sales, over 40 million people suffering from HIV are completely ignored by fake DeSci platforms. Real Decentralized Science was created to solve humanity's most urgent health crises. As the original creators of this sector, we brought the first real-world example of DeSci to life with innovative HIV cure research, sticking to the true philosophy of open science. Read the actual science here: pmc.ncbi.nlm.nih.gov/article…
5
6
210
Jonathan Fior🇮🇹 retweeted
BREAKING 🔴 Trump says he’ll be taking over Kharg Island
233
707
5,360
424,657
Jonathan Fior🇮🇹 retweeted
Replying to @ItsSnibby
Thank you for the interaction and useful questions. Existing liquidity is open and will flow naturally into our system because we are bridging traditional Web2 Real World Assets (RWAs) with an ultra-accessible Layer 1 infrastructure. Here is how INNBC Chain breaks the classic loop: 1. Seamless Interoperability & Dynamic Bridges. We are building fully trustless, decentralized bridges to allow capital to enter and exit the INNBC Chain fluidly. LPs won't find a closed loop, but a high-throughput environment with near-zero transaction fees and hyper-fast confirmation times, creating an arbitrage and yield environment far more profitable than congested legacy chains. 2. Radical Staking Democratization (No Entry Barriers). Unlike Ethereum, which acts as an elite network requiring a steep entry barrier of 32 ETH to run a validator node, INNBC Chain is built on absolute democracy: •Zero minimum balance requirements: Anyone holding $INNBC can instantly stake their tokens natively and earn fees. •50/50 Fee Split: Dedicated validators receive 50% of network gas fees, while the remaining 50% is routed directly to users who stake their tokens. This yields organic, continuous returns purely based on ecosystem volume, not printing infinite inflation. 3. Concrete Web2 RWAs (@Steam Integration). Our traction on Steam is a deliberate, strategic moat. These are traditional Web2 games with no native Web3 components due to Steam's guidelines: •Anti-Speculative Anchor: By keeping these assets detached from pure crypto speculation, their stable Web2 revenue serves as a financial backstop for the chain. •Ecosystem Support: Game revenues are channeled back into the ecosystem to support the network during market downturns while introducing a massive, mainstream audience to our brand completely outside the crypto bubble. 4. Pioneering DeSci Ecosystem (HIV & Oncology Assets). The ultimate RWA engine of INNBC Chain is the funding and clinical development of decentralized science. Our founder, Jonathan Fior (@JonathanFior), is the pioneer who effectively initiated the DeSci movement back in 2016 by independently funding and publishing the world's first peer-reviewed in vivo HIV cellular therapy study outside of traditional university grants (pmc.ncbi.nlm.nih.gov/article…). We don't deal with theoretical roadmaps: •Real Architecture: Our data validation infrastructure published in Springer Nature's BMC Medical Informatics has been officially cited by Harvard University medical researchers in advanced digital-twin health frameworks (link.springer.com/article/10…). •High-Value Pipeline: The long-term upside of our pipeline (HIV, oncology, and regenerative medicine) provides the network with valuable biotech asset backing, entirely cutting out traditional pharmaceutical gatekeepers and institutional conflicts of interest. The upcoming launch of the INNBC Chain is the culmination of a decade-long journey of independent science. Read our fully updated Whitepaper here: github.com/InnovativeBiorese… 🧬⛓️
1
1
155
Jonathan Fior🇮🇹 retweeted
Through on-chain funding, a researcher can bypass traditional university gatekeepers to raise capital. Those funds are then used to hire specialized, private Contract Research Organizations (CROs) to execute the physical in vivo experiments and clinical trials in certified facilities after you write the protocol. This is exactly how our peer-reviewed HIV study was conducted and funded on-chain, delivering unique in vivo data on SupT1 cells as decoy targets without relying on traditional institutional infrastructure: pmc.ncbi.nlm.nih.gov/article… Our biomedical DApp completes this cycle: it is used to register, timestamp, and secure these newly generated scientific data streams directly on-chain, protecting intellectual property from tampering or censorship bmcmedinformdecismak.biomedc… Welcome to the new paradigm.
1
5
5
400
Jonathan Fior🇮🇹 retweeted
🚀 INNBC is redefining the space: No financial promises, just TANGIBLE PRODUCTS. After the massive success of INNBC STARFIGHTER on @Steam—with over 14,000 licenses activated in just over a month and incredible feedback from the community—we are not slowing down. 🕹️🔥 The next wave of the INNBC ecosystem is coming. Here is what’s next: 1️⃣ INNBCswap 🔄 Our high-performance DeFi Aggregator. Built to compete with the giants like @1inch and @KyberNetwork, using proprietary tech to find the fastest and cheapest routes across all major chains. This is the future heart of our network. 2️⃣ INNBC L1 Chain ⛓️ A next-gen Layer-1 blockchain devoted to DeSci and Gaming. ⚡ 65,000 TPS 🛠️ EVM Compatible (Dev friendly) 🪙 $INNBC as native gas token (The official tech upgrade for our 2018 pioneer DeSci token). 3️⃣ INNBC Wallet 🛡️ The ultimate crypto wallet. Designed to be the snappiest and most intuitive UI on the market. Native support for INNBC Chain all major blockchains. We don't talk. We build. Watch closely. 👁️ #INNBC #DeSci #Gaming #L1 #DeFi #Steam #Starfighter #Web3 #Crypto #Buidl 👉 Check our latest release on Steam: store.steampowered.com/app/3…
10
10
24
2,158
Jonathan Fior🇮🇹 retweeted
70,938
96,972
909,101
98,930,808
Jonathan Fior🇮🇹 retweeted
Replying to @cz_binance
When we talk about ambition, it is profoundly surprising that the very leadership shaping the crypto ecosystem displays such a massive scarcity of vision. True leadership isn't measured by how much venture capital capitalizes on the trend of the month, but by the permanent structural value left behind. There is a baffling disconnect in choosing to fund mediocrity darlings that launch speculative DAOs and pump-and-dump tokens without producing peer-reviewed studies like @BioProtocol, rather than supporting meritocratic organic founders who originally built DeSci from the ground up like @InnBioresearch that created DeSci in 2016. Settling for manufactured trends instead of backing proven, hard-earned scientific validation isn't practical; it is simply a lack of real ambition. True talent cannot be bought, and real persistence is forged when you have to fight for every inch of progress rather than living on Binance's pocket. A prime example is the #INNBC ecosystem, which pioneered decentralized biomedical data storage on the BNB Smart Chain without a single dollar of VC backing. While heavily funded protocols generate noise and marketing hype, INNBC focused on core execution and academic validation. The resulting foundational study was published by world's most important scientific network @SpringerNature, establishing a legitimate gold standard for the industry. link.springer.com/article/10… This exact research has now been formally cited in a framework by Harvard University, anchoring the names of both INNBC and BNB Smart Chain/Binance into the highest tier of global academic excellence (by the way, you are welcome!). This is the ultimate certification that merit and grit outlast synthetic hype. Capital without rigorous execution only breeds low-ambition mediocrity and temporary marketing trends. True decentralized science isn't a series of speculative cycles; it is built on verifiable results, peer-reviewed perseverance, and independent structures that command the attention of the world’s leading universities. True ambition lies in recognizing and standing with the creators who actually deliver the core science, proving that the most glorious victories are those won entirely on merit. This is the ultimate proof that money can buy visibility, but it can never buy talent or resilience. On one side of this industry, we see project founders like @paulkhls, @NateHindman and @jamessinka who act like spoiled children, coddled in luxury and rained upon with bags of VC money from the sky without ever having to earn their position or fight through a single day of real hardship. They were handed everything on a silver platter, yet they produced absolutely nothing of structural value, failing to deliver any real results recognized by the scientific community in the field of DeSci. Instead, they reduced the noble concept of decentralized science to a series of speculative pump-and-dump tokens that lack scientific foundation and ultimately damage Binance’s own reputation by making the whole sector look like a farce. On our side, we come from the ground up; we fought with our teeth and nails for years to build our reality from absolute zero, without a single dollar from VCs or corporate handouts. Our validation didn't come from a marketing budget, but from the brutal peer-review process @SpringerNature, leading our work to be cited by Harvard University. While their heavily funded projects showcase nothing but financial toxicity, our independent journey represents the true gold standard of DeSci. This industry may completely lack meritocracy, routinely choosing to ignore genuine talent in favor of well-connected and overfunded mediocrity, but we simply do not care. We do not need their permission or their funds to exist. We will keep pushing forward, fighting against the current, and creating real, undeniable innovation on our own terms, because true strength is forged in struggle, not in a cushion of unearned capital.
1
4
7
635
Jonathan Fior🇮🇹 retweeted
Replying to @beakerdao
WARNING❌❌❌: This article is flat out lying regarding the origins of DeSci Legitimacy in Decentralized Science is defined by peer-reviewed publications, not financial PR statements. The historical timeline of DeSci was established in 2016 when InnovativeBioresearch (the issuer of $INNBC) published the first study produced by a blockchain project on HIV (pmc.ncbi.nlm.nih.gov/article…), effectively pioneering and creating the DeSci field. By contrast, companies like Molecule lack any primary scientific publications. In 2024, we solidified this legacy by publishing the pillar DeSci study in @SpringerNature. Now cited by Harvard University, this work officially introduced the decentralized science framework to the global scientific community (link.springer.com/article/10…). Without peer-reviewed validation in reputable journals, claims remain speculative. We remain committed to real, documented science.
4
5
562
Jonathan Fior🇮🇹 retweeted
Replying to @SpectruthDAO
Citing Stanford’s success doesn’t grant you scientific legitimacy by proxy. Science is not about emotional appeals or bypassing protocols under the guise of 'speed'; it’s about the rigorous validation of original data. The peer-review process isn't about 'funding journals'—it is the fundamental safeguard that protects patients, including veterans, from unverified claims and pseudoscience. If a project is unable or unwilling to subject its own data to expert scrutiny, it cannot claim to be 'science.' True respect for trauma survivors means providing them with treatment that has passed the highest standard of verification, not marketing scripts. Without peer-review, it’s not DeSci; it’s just a claim. This is a giant red flag and perfectly supports @DjGriffith concerns. Claiming to represent 'science'—whether DeSci or traditional—while intentionally bypassing the peer-review process is the very definition of a fraud. Using emotional appeals about veterans to shield unvalidated data isn't 'innovation'; it’s a dangerous exploitation of a vulnerable community. If your data hasn't been subjected to rigorous expert scrutiny, it is not science—it is marketing masquerading as medicine. Relying on the reputation of institutions like Stanford to legitimize your own unvetted claims only reinforces the fact that this is a scam. True DeSci is built on transparency and verification, not on avoiding the standards that keep patients safe. Anything less is a fraud, plain and simple.
2
3
380
Jonathan Fior🇮🇹 retweeted
Big milestone for us: We’ve officially published the INNBC STARFIGHTER Engine on GitHub — the high-performance JavaScript game engine behind our @Steam released shoot ’em up. Built with JavaScript Electron, integrated with Steam APIs, and engineered for responsive 60 FPS arcade gameplay, the engine includes: • performance-focused asset warm-up/caching • full Steam achievement integration • online multiplayer/lobby support • gamepad support • production-ready architecture shipped in a real commercial game This is more than a code release — it’s proof that high-value game technology can be built in JavaScript and brought all the way to market. The engine is source-available and will be offered under commercial license to developers and studios interested in building with it. GitHub: github.com/InnovativeBiorese… Licensing / partnerships: contact us #gamedev #javascript #indiedev #electron #steamworks #multiplayer #innbc #steam
6
17
2,261
Jonathan Fior🇮🇹 retweeted
🚀 Massive Easter surprise! 🐣 We are thrilled to announce that the specialized press is shining a spotlight on INNBC STARFIGHTER! A huge shoutout to @spaziogames for featuring us as one of the top free-to-play titles on #Steam this holiday season! 🕹️✨ The 90s-inspired arcade action is taking off. If you haven't joined the battle yet, now is the perfect time to jump in! 🛰️👾 Check out the news here: spaziogames.it/notizie/8-pic… #IndieDev #RetroGaming #Steam #GamingNews #PCGaming #SpazioGames #INNBCStarfighter #INNBC
Ogni tanto #Steam riesce ancora a ricordare una cosa semplice: esistono giochi gratis che puoi scaricare e tenere per sempre, senza condizioni. spaziogames.it/notizie/8-pic…
2
6
10
1,946
Jonathan Fior🇮🇹 retweeted
🚀 INNBC PILOTS: MISSION BRIEFING!🚀 Struggling with the high-speed chaos of our newly released game #INNBCStarfighter? We've just released the Official Developer Strategic Guide to help you dominate the leaderboard! Learn the "Ramming" loop: 🔹 Collide with Blue Power-ups ⚡ 🔹 Instant Ammo & Shield recharge 🛡️ 🔹 Maintain 'Double Fire' state 🔥 Can you beat my 700 winning score? Show me what you got! 🏆 Read the full guide & watch the walkthrough on @Steam: 👇👇👇 store.steampowered.com/news/… 🏆 Real Product. Real Utility. Real Assets. 🏆 Unlike many speculative projects, INNBC is built on real-world products, not hype. We focus on results, gameplay, and tangible value. #IndieGame #Steam #Shmup #GamingCommunity #BulletHell #SciFi #PCGaming #IndieDev
6
7
1,007
Jonathan Fior🇮🇹 retweeted
🚀 THE ULTIMATE DEPLOYMENT: INNBC STARFIGHTER IS LIVE! We didn't just build a game; we built a bridge. While others sell hype, we deliver REAL UTILITY and REAL SCIENCE. INNBC STARFIGHTER is officially AVAILABLE NOW on @Steam! 🎮🔬 Why is this a game-changer? Because we are merging Hardcore Multiplayer Gaming with Decentralized Science (DeSci). ✅ BEYOND SPECULATION: We are moving away from pure hype. This is a functional, high-octane product with a real mission. ✅ HARVARD VALIDATED: Our latest research is validated by Harvard and published on Springer Nature. We live by scientific validation, not digital collectibles. ✅ DE-SCI INTEGRATION: Experience the power of the INNBC ecosystem in a full-scale Sci-Fi universe. ✅ MULTIPLAYER CO-OP: Team up, fight, and explore an innovative world driven by cutting-edge tech. ✅ FREE TO PLAY: We removed every barrier to entry. Just like science should be open to everyone, our world is open to you. No barriers. Just access. Stop waiting for the future. PLAY IT NOW! 👇 Download for FREE on Steam: store.steampowered.com/app/3… #Steam #DeSci #Gaming #Harvard #Nature #Science #Multiplayer #INNBC #IndieDev #SciFi @anndylian @pumpdotscience @DeSciNews @cz_binance
3
5
11
904
Jonathan Fior🇮🇹 retweeted
Honored to announce that our @SpringerNature publication (link.springer.com/article/10…) has received its second major international citation! 📄✨ Following Harvard, the recent "BirthChain: a blockchain platform for birth certificates" study in @FrontiersIn Blockchain now references our work as a technical pillar for BNB Smart Chain DeSci implementation 🌐 frontiersin.org/journals/blo… Why this is a major "win" for INNBC research and how it establishes a gold standard in DeSci: • Global Validation: Being cited by researchers at Harvard and now in "Frontiers in Blockchain" confirms that our research is being used as a reference by top-tier institutions to build future blockchain infrastructure. • Technical Authority: The citation in the context of EVM-compatible networks (Ethereum, Polygon, BNB) proves that our study is a practical reference for real-world blockchain engineering. • Journal Prestige: Frontiers in Blockchain is a community-driven, peer-reviewed journal led by experts from institutions like University College London, ensuring only high-quality research is disseminated. #AcademicTwitter #ResearchImpact #SpringerNature #BNBChain #PeerReview @cz_binance @anndylian @DeSciNews @BNBCHAIN @binance
7
5
13
1,011
Jonathan Fior🇮🇹 retweeted
There is a very clear 'we' and 'they': those who follow the scientific method and those who don't. Suggesting that science is just a 'tiny part of our journey' is a dangerous excuse to bypass the rigor that prevents fraud. Without selection criteria based on verifiable data, you are rewarding those who speak the loudest, not those who produce the best science. This 'openness' without standards is exactly how scams flourish and how the credibility of #DeSci is destroyed. As the original creators of Decentralized Science, we set the gold standard for legit DeSci by having our blockchain-based biomedical research approved for publication in the world's most reputable scientific network, @SpringerNature, and our work has been cited by Harvard University link.springer.com/article/10… Real #DeSci is about empowering researchers through better systems, not lowering the bar until the 'science' disappears. If your platform can’t distinguish between a peer-reviewed breakthrough and a marketing pitch, it’s not evolution—it’s a lack of accountability that penalizes serious scientists.
4
5
256
Jonathan Fior🇮🇹 retweeted
Replying to @VitalikButerin
The debate over incentives misses a brutal reality: crypto has become a safe haven for subpar products that would instantly fail in any competitive traditional market. When you can monetize 'narrative' and token speculation before delivering actual value, you attract founders who aren't built for survival in the real world. We aren't lacking incentives; we are suffering from a concentration of low-quality talent using the 'airdrop meta' to mask mediocre engineering and zero PMF. Instead of crying for more incentives, devs should focus on building apps that stand on their own merits. The ultimate proof of quality is a product that doesn't need a token to justify its existence. Raise the bar, or leave the market.
3
4
164
Jonathan Fior🇮🇹 retweeted
Buzzwords like 'inclusive' and 'community-driven' don't validate data. Science isn't about 'permission,' it's about evidence. By funding 'curious minds' without requiring verifiable research or peer-reviewed baselines, you aren't accelerating discovery—you are subsidizing noise. Real scientists aren't 'gatekeepers'; they are the ones doing the hard work of validation. If your platform can't distinguish between a rigorous experiment and a pseudoscience pitch, you are actively harming the credibility of the #DeSci movement. Funding hype is exactly the opposite of investing in humanity.
1
4
144
Jonathan Fior🇮🇹 retweeted
Replying to @VitalikButerin
Vitalik, your transition from 'dopamine betting' to 'generalized hedging' is mathematically elegant, but it seems to fall into the same trap that haunts most of this industry: over-engineering a solution for a problem that is fundamentally about human psychology, not just capital efficiency. You argue that we can replace fiat with a personalized basket of prediction market shares managed by local LLMs. While this solves the 'centralization' problem on paper, it introduces a massive 'cognitive tax' on the user. Money, in its fiat form, is a coordination technology designed to reduce complexity. Its value lies in the fact that I don’t have to think about it. By turning every expense into a hedging position, you are asking every citizen to become a professional risk manager. Even with an AI assistant, you are replacing 'trust in a central bank' with 'dependence on an algorithmic oracle' for basic survival. Furthermore, you underestimate why 'corposlop' dominates. High-volume markets like sports or price bets exist because they aggregate global attention. If we fragment these markets into personalized indices for local goods and services, we run into a massive liquidity fragmentation problem. Without the 'naive traders' or speculators providing deep liquidity, these micro-hedging markets will have such high spreads that the cost of insurance will likely exceed the cost of inflation itself.  The reason we see so much 'corposlop' isn't just a lack of vision; it's that building truly useful, frictionless products is hard. Most teams choose the 'dopamine' route because they lack the skill to compete with the seamless UX of traditional finance. They use the token as a crutch to avoid the brutal reality of product-market fit. We don't need a more complex way to gamble against our cost of living. We need products that provide stable, predictable value without requiring a PhD in game theory to buy a loaf of bread. If the 'next generation of finance' is more complex than the one it tries to replace, it will remain a sandbox for the 1% of early adopters, while the rest of the world sticks to the simplicity of fiat—precisely because it doesn't require a strategy meeting to go grocery shopping
2
5
302
Jonathan Fior🇮🇹 retweeted
Replying to @paulkhls
Let’s distinguish between Scientific Development and Market Positioning. In its current form, your narrative leans more toward high-stakes PR rather than decentralized science (DeSci). 1. Self-Reported Benchmarks !== Science: In science, "shattering benchmarks" in a self-published PDF (arXiv) without independent, third-party validation is just a brochure. Real DeSci requires peer-review. Our blockchain research has been published in @SpringerNature and cited by Harvard (link.springer.com/article/10…). This is validated science; yours reads as a sales pitch. 2. The "fee" factor: You are asking the community to pay for a 'wrapper' system and stake tokens to access it. Why? We’ve already developed and released a free, open-source AI agent that performs the same literature synthesis using Grok 3 PubMed API (github.com/InnovativeBiorese…). In the true spirit of DeSci, if a tool is useful for humanity, it should be accessible, not gated behind a token. 3. Virtualism vs. Reality: You speak of "autonomous science machines" and "Shopify layers". This is virtualism. Real science needs laboratories and funding for experiments (like our published HIV cure research pmc.ncbi.nlm.nih.gov/article…). Claiming an "emergent early AGI" will manage funds is a massive red flag. Science needs human accountability and rigorous methodology, not a black-box algorithm designed to keep holders "patient" while they "sacrifice" for a token. 4. True DeSci doesn't demand sacrifice from its holders; it delivers results for patients. Scientific progress is measured by patient outcomes and peer-reviewed data, not by the conviction of token holders. The current proposal appears to prioritize financial orchestration over methodological transparency. A "Shopify layer" for science introduces a middleman where DeSci aims for direct accessibility. 5. Until raw data is disclosed and benchmarks are independently verified, this remains a closed ecosystem—the antithesis of open, decentralized science. In a value-creation model, tools for the community should be accessible, and funding should derive from tangible technological utility, not from the "sacrifice" of participants.
4
10
345
Jonathan Fior🇮🇹 retweeted
Replying to @itchdoctor
It’s an inspiring story of tenacity, but we must be careful not to confuse "founder mode" with "DeSci in action". Actually, DeSci was born to elevate scientific standards through decentralization, not to bypass them. As the founders of the original project that created DeSci back in 2016—when we pioneered the use of SupT1 cells as decoy targets for HIV (pubmed.ncbi.nlm.nih.gov/2712…) —we believe that the only way to disrupt the status quo is to be more rigorous than the establishment, not less. The true power of DeSci lies in proving that high-level science can happen outside traditional silos, provided it survives the fire of peer review. Our latest study, recently cited by Harvard, is a testament to this: you don't need a legacy institution to do "big science", but you do need transparency and validation: doi.org/10.1186/s12911-024-0… In biotech, "no papers and no grants" isn't a badge of honor; it’s a red flag for lack of reproducibility. Real innovation doesn't hide from peer review—it uses it to prove its worth to the world!
2
5
8
237