DQ antibodies #KKNEPHBYTES #Transplant #immunology @CMEINDIA1 @DrAkshayaJ @DrMedhavi_G @drshyambansal @hafeeq_benil @hardik4u24 @isn_india @myadla @NDTsocial @priti899 @sciqst @thisis_drgsp @nephromythri @JasmineNephro

Virtual Cross Match Pitfalls. #transplant #Immunology #KKNephBytes @CMEINDIA1 @DrAkshayaJ @DrMedhavi_G @drshyambansal @hafeeq_benil @hardik4u24 @isn_india @myadla @NDTsocial @priti899 @sciqst @suhalikapath @arvindcanchi @Arunkr_Dr

International Faculty Spotlight #ISNCON26 A pioneering physician-scientist whose work has transformed our understanding of kidney disease & preeclampsia, Dr. Anant Karumanchi @ananthmsn34 will deliver the prestigious K S Chugh Oration✨ 📍 Kochi 📅 Dec 17–20, 2026 Register now⏰

Renal Allograft Journey #Failinggraft #Failedgraft #Transplant #KKNephBytes @DrAkshayaJ @DrMedhavi_G @drshyambansal @hafeeq_benil @hardik4u24 @isn_india @myadla @priti899 @arvindcanchi @CMEINDIA1

Blood transfusion amd Alloimmunization #Transplant #Immunology #KKNephBytes @arvindcanchi @CMEINDIA1 @DrAkshayaJ @DrMedhavi_G @drshyambansal @hafeeq_benil @hardik4u24 @isn_india @myadla @priti899 @suhalikapath @ShreshtaT @JJayameena @AnjanaGopal9 @DrAnjanaAsokan @hafeeq_benil

Post transplant TMA. Key points #transplant #KKNephBytes @CMEINDIA1 @DrAkshayaJ @DrMedhavi_G @drshyambansal @hafeeq_benil @hardik4u24 @myadla @priti899 @ShreshtaT @suhalikapath, @arvindcanchi

Post transplant diarrhoea #transplant #diarrhea @arvindcanchi @CMEINDIA1 @DrAkshayaJ @DrMedhavi_G @drshyambansal @hafeeq_benil @hardik4u24 @IamGopambuj @isn_india @myadla @priti899 @suhalikapath @

TCMR with Hemorrhage Key Points #Transplant #Biopsy #KKNephBytes @arvindcanchi @CMEINDIA1 @DrAkshayaJ @DrMedhavi_G @drshyambansal @hafeeq_benil @hardik4u24 @isn_india @myadla @ShreshtaT @

Paired Kidney Donation Guidelines okayed by the Karnataka Government. This is great news.

ABCDE frame work New Era In Kidney Health #KKNephBytes #CKD @DrAkshayaJ @drshyambansal @hafeeq_benil @hardik4u24 @isn_india @NDTsocial @priti899 @ShreshtaT @suhalikapath @JJayameena @nephromythri @arvindcanchi @CMEINDIA1 @ISNkidneycare

HLA-B15: A Hidden Story Beneath the Surface #KKNephBytes #Immunology @DrAkshayaJ @drshyambansal @hardik4u24 @isn_india @priti899 @sciqst @ShreshtaT @suhalikapath @arvindcanchi @hafeeq_benil @JJayameena

Membranous Nephropathy 🔬Anti-PLA2R = used for Diagnosis , Prognosis, Monitoring 📊 Risk stratify: Based on Proteinuria eGFR AntiPLA2R 🟢 Low risk→ Supportive 🟡 Mod→ Observe ± RTX 🔴 High→ Rituximab / Cyclophosphamide Steroid 👍for Antigens: VA @KKNephBytes 💯 #KDIGO

Honoured to be a part of this amazing team !!✨🎉🗺️ Looking forward to #ISNWCN & Japan 🇯🇵 !! @ISNWCN @Alexgr23 @Glomkeeper @manishmedicine1 @Arunkr_Dr @acssjr @brammahin @NephroSeeker @dra_miliflores @Dilushiwijay @GabyNeph @HarukaM_5 @KajareeG @DrMedhavi_G @deniise_am @myadla

Dormant but Dangerous: DQ Will Return #KKNephbytes #transplant #immunology @DrAkshayaJ @drshyambansal @hardik4u24 @isn_india @ShreshtaT @priti899 @suhalikapath @arvindcanchi

"😎Glad to see our data, hitting the press! 🚀 ✔️ Driven by these findings, we’ve just kicked off an RCT 🎲 in the department comparing VKA💊 versus DOACs in NS. 💥Likely to move the needle on anticoagulation strategies in NS . share.google/XMWjELv8In2CR0M… @SaynaNorouzi @AKronbichler @myadla @SwarnalathaGud2

*When Positivity Misleads: Recognizing False Signals in SAB Testing* *********************** ⚡SAB positivity can represent artefact rather than true immunologic risk ⚡High MFI alone is unreliable without pattern and clinical context ⚡A broad, tapering (“long-tail”) pattern suggests non-specific reactivity ⚡Lack of sensitization history should prompt cautious interpretation ⚡FlowPRA and FCXM discordance helps identify non-clinical antibodies ⚡Absence of a shared epitope supports non-specific binding ⚡Misinterpretation can lead to false DSA assignment and inflated cPRA ⚡Result in unnecessary exclusion of compatible donors ⚡Always interpret SAB results in integration with clinical and laboratory correlation ⚡Pattern recognition is more reliable than numerical thresholds #KKNephBytes #Immunology @arvindcanchi @DrAkshayaJ @drshyambansal @hardik4u24 @isn_india @priti899 @suhalikapath @AnjanaGopal9 @raja_1980 @dr_sourabha @iamnephrologist

*HLA-DQ Antibodies: The Silent Cracker That Starts the Blast* *************************** ⚡HLA-DQ antibodies are the most common de novo DSA ⚡HLA-DQ DSA have the worst graft outcomes (ABMR, TG, graft loss) ⚡DQ mismatch carries the highest risk of sensitization (↑cPRA) ⚡ HLA-DQ has dual polymorphism (α β chains) ⚡Can form multiple heterodimers (cis trans pairing) ⚡ More heterodimers → more epitopes → higher immunogenicity ⚡ HLA-DQ shows low expression but high pathogenicity ⚡ Expression is delayed but sustained → chronic rejection ⚡ DQ antibodies activate Akt / S6 / IL-6 pathways ⚡ Current matching underestimates DQ risk ⚡ Eplet/pairing-based analysis > antigen matching #KKNephBytes #Immunology @arvindcanchi @DrAkshayaJ @drshyambansal @hardik4u24 @isn_india @priti899 @suhalikapath @JJayameena

“World Kidney Day Awareness: CKD Do’s and Don’ts " #WorldKidneyday @DrAkshayaJ @worldkidneyday @arvindcanchi @drshyambansal @taruna_pahuja @KKNephBytes @YashenduSarda @isn_india