Did you know ketones may be linked to better metabolic health even without a ketogenic diet? 🔬 That's just one of the findings from last week's Spotlight on Keto Research. Subscribe to our weekly LinkedIn newsletter and stay ahead of the science. Click the link to join: linkedin.com/posts/ketomojo_… #KetogenicResearch #MetabolicHealth #CardiometabolicHealth

Most people take the train to St. Moritz for the views; we're here for the metabolic science. @keto_live updates to come. Mojo on 🩵 #KetoLive2026 #MetabolicHealth #KetogenicDiet #KetogenicResearch

We were proud to fund this important pilot trial of a new metabolism-based treatment for Anorexia Nervosa. Please share with anyone who needs to know.

Will we see you there this year? 👀 @ipmcongress #ipmcongress #Keto #MetabolicHealth #IPMCongress26

What if your “normal” blood sugar isn’t telling the full story? Glucose can stay in range while insulin levels rise, masking early metabolic dysfunction. This article explains why this happens and how ketone levels can provide deeper insight. 🔗 Link in bio. #MetabolicHealth #InsulinCompensatedEuglycemia #Ketones #BloodGlucose #KetogenicDiet #RootCauseMedicine

Ketogenic diets historically have not been recommended for people with anorexia nervosa (AN), largely because of concerns about weight loss. However, a new feasibility study explored whether a weight-maintaining ketogenic dietary therapy could be safely implemented in adults with AN. Twenty-two women who were weight-restored or mildly underweight followed a ketogenic diet providing approximately 70% of calories from fat, 20% from protein, and 10% from carbohydrate for 14 weeks. Blood ketones were monitored daily during the first two weeks and weekly thereafter, with a target BHB range of 0.5–3.0 mmol/L. Key findings: 🔹 82% (18/22) completed the intervention 🔹 72% of completers no longer met the criteria for diagnosis of AN 🔹 72% of completers achieved depression scores within the normal range 🔹 Improvements were also seen in anxiety, self-esteem, body dissatisfaction, and mealtime distress 🔹 BMI remained stable, with no clinically significant weight loss 🔹 No serious adverse events occurred This was a small, uncontrolled feasibility study, so the findings should be considered preliminary. However, the results support further investigation of ketogenic therapy as a potential adjunctive approach for anorexia nervosa 💥 @GuidoFrank, Scolnick B, Beckwith C, Shott ME, Kilty S, Swindle S, Lutter M, Rho JM. Symptom impact and safety of ketogenic therapy in adults with anorexia nervosa: a feasibility trial. Communications Medicine. 2026;6:315 📌 Link to study: doi.org/10.1038/s43856-026-0… 📌 Find more research summaries on our website: keto-mojo.com/research/ #AnorexiaNervosa #KetogenicMetabolicTherapy #Ketosis #MentalHealthResearch #MetabolicHealth

Migraines aren’t “just headaches.” They can disrupt your focus, energy, mood, and quality of life. Because what if it isn't a nervous system problem, but a metabolic one? @DrElenaGross explores how impaired brain energy metabolism, mitochondrial function, blood sugar instability, and inflammation may all play a role in migraine susceptibility. Ready to connect the dots between metabolism and migraines? 👉 Read more here: bit.ly/3PDU5Up

🚨 A recent randomized clinical trial compared different weight loss approaches in adults with obesity In just 3 months, several diets outperformed the classic Mediterranean approach for losing weight: 🥩 Ketogenic diet: −3.8 kg (8.3 lbs) greater weight loss ⏳ Alternate-day fasting : −3.1 kg (6.9 lbs) greater weight loss 🕒 Late time-restricted eating: −2.3 kg (5 lbs) greater weight loss 🌅 Early time-restricted eating: −1.22 kg (2.7 lbs) greater weight loss All diets reduced intake by 600 calories per day, fat loss was highest with mADF and early time-restricted eating, and there were no major changes in lean mass or heart health markers. 📉 Keto and intermittent fasting may lead to greater weight loss than a standard calorie-restricted Mediterranean diet, although long-term results require more study. — Martínez-Montoro JI, Bandera B, Gutiérrez-Bedmar M, Gómez-Pérez AM, Macías-González M, Moreno-Indias I, Tinahones FJ. Effect of a ketogenic diet, time-restricted eating, or alternate-day fasting on weight loss in adults with obesity: a randomized clinical trial. BMC Med. 2025;23:368. 📌 Link to study: bit.ly/49idroF 📌 Find more research summaries on our website: 🔗 Research link in bio. #KetogenicDiet #IntermittentFasting #ADF #Research #MetabolicHealth

Your gut does more than digest food. It influences everything from immunity to inflammation. Good news: you can support your gut microbiome while following a ketogenic lifestyle. This article shares six evidence-based strategies to promote gut health on keto, including whole foods, fermented foods, collagen, and more. 🔗 Link in bio #Ketogenic #MetabolicHealth #Microbiome #LowCarbLiving

For #MentalHealthAwareness Month, we're highlighting metabolic psychiatry and its potential to change how we treat mental health. New research from the @BaszuckiGroup may hold answers. #MetabolicHealth #KetogenicResearch #RootCauseMedicine

Can carbohydrate restriction directly improve beta-cell function—independent of weight loss? In a 12-week randomized controlled trial, adults with type 2 diabetes followed either: 🥑 A ketogenic diet (~9% carbohydrate) 🍞 A low-fat diet (~55% carbohydrate) Participants received all foods and met weekly with a dietitian, and the diets were designed to maintain weight in both groups. The ketogenic diet led to greater reductions in a key marker of beta-cell stress (proinsulin-to-C-peptide ratio, or PICP): 📉 ~56% greater reduction in fasting PICP 📉 ~49% greater reduction in post-challenge PICP These reductions were associated with improvements in insulin secretion during hyperglycemic clamp testing. Additionally, body weight remained stable, suggesting that a ketogoenic diet without weight loss may help reduce beta-cell workload. This study adds to the evidence that lowering carbohydrate intake may support beta-cell function in type 2 diabetes 💥 — Yurchishin ML, Finn AR, Fowler LA, Vere-Whiting SL, Gower BA. Greater reduction in the proinsulin-C-peptide ratio with a ketogenic vs control diet in patients with type 2 diabetes. J Endocr Soc. 2026; 10:bvag073. 📌 Link to study: doi.org/10.1210/jendso/bvag0… 📌 Find more research summaries on our website: keto-mojo.com/research/ #MetabolicHealth #Diabetes #KetogenicDiet #NutritionScience

Food is more than fuel. It shapes our memories, our relationships, and often our sense of identity. And when we’re facing serious health challenges, those emotional and cultural connections to food don’t simply disappear; they matter even more. In this guest blog post, registered dietitian Martha Tettenborn explores how a ketogenic approach can be adapted to support both metabolic health and the human side of eating, especially in the context of cancer and other complex conditions. 🔗 keto-mojo.com/blog/cancer-su… #MetabolicHealth #Ketosis #KetogenicNutrition #CancerSupport

Mental health and metabolic health may be more connected than we once thought 🧠 Emerging research suggests ketogenic therapy may help support brain energy, inflammation, mood stability, and metabolic health in certain psychiatric conditions. But one important takeaway? Progress > perfection. Sleep, stress, hydration, blood sugar stability, and consistency all play a role in supporting both metabolic and mental wellness. This Mental Health Awareness Month, we’re exploring the growing field of metabolic psychiatry — and practical ways ketogenic therapy may support brain health. Read more: keto-mojo.com/blog/keto-ment… #MetabolicHealth #KetogenicLifestyle #KetoDiet #RootCauseMedicine

Join us at the 6th International Keto Live Conference in Switzerland 🇨🇭 📅 June 8–12 | The Hotel Reine Victoria in St. Moritz, Engadine An intimate meeting of minds, unified by the latest in metabolic science, surrounded by the stunning Swiss Alps ⛰️ ✔ Direct access to the experts shaping the future of keto. ✔ Meaningful connections with a global ketogenic community of people who truly “get it." ✔ Delightful gourmet cuisine - thoughtfully created by the in-house chef to be deeply ketogenic, and anything but typical conference fare The most respected voices in ketogenic science will be there, including: @IainCampbellPhD, @drtomasduraj, Dr. Guido Frank, @AKoutnik, Dr. Kirk Nylen, Dr. John Schoonbee, @AdrianSotoMota, @lowcarbGP, @drjenunwin, AND our very own Dr. Sofia Deloudi! Come experience it for yourself. Reserve your spot at Keto Live: 👉 european-keto-live-centre.co… Explore more upcoming keto & low-carb events across Europe: 👉 keto-mojo.com/keto-low-carb-… #KetoLive2026 #Ketogether #KetoConference #KetoMojoLive #MojoMeetup #KetoFun #MetabolicHealth #KetogenicResearch

🔍 What happens to liver health markers when keto-adapted individuals switch to high carbs? A small study of long-term keto-adapted women (avg ~4 years) found that after just 21 days of high-carb intake: • ALT ↑ 85% • GGT ↑ 29% • Insulin resistance (HOMA-IR) more than doubled • ALT/AST ratio also increased All markers returned to baseline after resuming keto, suggesting reversibility. 📊 GKI closely tracked these shifts, highlighting its potential as a monitoring tool. Takeaway: Even short-term high-carb intake may disrupt liver-related metabolic markers in keto-adapted individuals. — Cooper ID, Petagine L, Soto-Mota A, Duraj T, Scarborough A, Norwitz NG, Seyfried TN, Furoni MA, Kyriakidou Y. Ketosis Suppression and Ageing (KetoSAge): The Effect of Suppressing Ketosis on GKI and Liver Biomarkers in Healthy Females. Livers. 2025;5(3):41 📌 Link to study: bit.ly/4d6mom3 📌 Find more research summaries on our website: bit.ly/49p9WfU #Ketogenic #MetabolicHealth #LiverHealth #Ketosis #InsulinResistance #Research

🚨 New randomized trial shows a personalized ketogenic diet can improve real-world function in McArdle’s disease, a rare genetic disorder that blocks the breakdown of muscle glycogen and makes exercise painful and fatiguing. In a 6-month single-blind RCT, adults with McArdle’s disease – also known as glycogen storage disease 5 (GSD5) – followed a ketogenic diet or maintained their usual diet. Key changes in those on the ketogenic diet: - VO₂ peak rose by 2.7 ml/kg/min - Walking distance in 12 minutes increased by 180 feet (55 meters) - BMI decreased by 2.3 kg/m² - No serious adverse events were reported - 5 participants continued the diet post-trial and reported sustained benefits 3 years later This is one of the longest ketogenic diet trials in GSD5 to date, supporting this dietary therapy as a safe, sustainable strategy to improve aerobic capacity and physical performance in this rare metabolic condition 💡 — Martinuzzi A, Musumeci O, Stefan C, Vinante E, Ferrati A, Perillo C, Pesenti N, Toscano A . Low-carbohydrate ketogenic diet in Mc Ardle’s disease: a single-blinded randomized controlled trial. J Neurol. 2025_;_ 272(698) 📌 Link to study: doi.org/10.1007/s00415-025-1… 📌 Find more research summaries on our website: keto-mojo.com/research/ #KetogenicDiet #McArdleDisease #GSD5 #Research

Low-carb doesn’t have to be complicated, expensive, or time-consuming. In this guest blog post, Dr. Mark Cucuzzella shows how simple, 10–15 minute conversations in primary care can lead to meaningful improvements in weight, A1c, and medication use, using real food and practical guidance. 🔗 bit.ly/3P2uAeW #MetabolicHealth #LowCarb #PrimaryCare #Nutrition

GLP-1 medications may help with weight loss, but emerging research suggests some weight lost on GLP-1s may come from muscle, not just body fat, especially without the right nutritional support. As we age, preserving muscle becomes even more important for metabolic health, energy, and long-term results. So how do you support your body after GLP-1s? ✔️ Our latest article offers insight into: ✔️ GLP-1s and muscle loss ✔️ How a ketogenic diet may support weight loss after GLP-1s If you’re thinking about life after GLP-1s, this is a must-read. 🔗 Read the full article at the link in bio.

Weight regain after stopping GLP-1 is common. But it may not be inevitable. One study found that people with type 2 diabetes who stopped GLP-1 therapy while following a ketogenic or low-carb diet: • Maintained weight loss after 1 year • Kept HbA1c below the diabetes threshold • Saw outcomes comparable to those who stayed on GLP-1 With the right strategy, long-term metabolic health is possible 🙌 Learn what to do next 👇 bit.ly/4cQn67X #MetabolicHealth #KetogenicDiet #LowCarb #Keto

💪 Can exercise intensity impact ketone levels during therapeutic keto? A recent case report suggests it can. In a glioblastoma patient, blood ketones reached ≥4.0 mM with high-intensity exercise, but not with walking or steady cycling on the same diet. The insight: intensity may play a bigger role than calories burned when aiming for deeper levels of ketosis. 📈 While more research is needed, this highlights an important consideration for those using keto as part of a therapeutic approach. 📌 Link to study: bit.ly/4tfkt4E 📌 Find more research summaries on our website: bit.ly/49p9WfU #KetogenicDiet #Glioblastoma #NutritionalKetosis #Exercise #MetabolicHealth