KircherLab is a bioinformatics / computational biology lab that studies genetic variant effects throughout the genome.

Joined May 2022
9 Photos and videos
Make your mark on the future of #PrecisionMedicine at #CRISPR25 Showcase #CRISPR methods for modulating the genome at scale🧬 Submit an abstract by 4 February for an opportunity to build your professional profile at the forefront of a global community 📎bit.ly/3Amz34N
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Join us at CRISPR and Beyond for a showcase of recent advances in the field. #CRISPR25  🗓️ 2-4 April 2025 Explore their potential impact on the future of #PrecisionMedicine with experts in #GeneEditing 🧬 📎bit.ly/3Amz34N 💸 Bursaries available #AcademicChatter
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‼️Save the Date!! #CRISPR and Beyond: Perturbations at Scale to Understand Genomes🧬✂️ Join us to explore new methods for modulating the #genome at scale. 🗓️ Dates: 2-4 April 2025 📩Email us to ask for e-updates about this meeting: conferences@wellcomeconnectingscience.org
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We are recruiting two computational biologists/bioinformaticians with ML expertise and a focus on genomics, variant effects and gene regulatory sequences in staff scientist and postdoc roles in Lübeck, Germany. Please find details here: kircherlab.github.io/contact…

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Martin Kircher retweeted
Excited to share the white paper for the IGVF Consortium, supported by @genome_gov Deciphering the impact of genomic variation on function rdcu.be/dSZdm

Understanding the function of an entire genome is no easy task! Most genes likely have more than one function. To understand the functional effects of genomic variation, NHGRI launched a consortium called Impact of Genomic Variation on Function (IGVF). genome.gov/news/IGVF
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Come and see posters of the lab at #ESHG2024 – Pia is presenting P20.013.B (award candidate) this afternoon and Mohan will present P16.084.D tomorrow afternoon. Very different work studying non-coding sequence effects with our collaborators at @NadavAhituv lab and @JShendure lab.
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Very proud of our PhD candidate Kilian presenting to a full audience at #ESHG2024. Congratulations to this great talk!
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#ESHG2024 is up to a great start in Berlin! So happy to see Svante filling the lecture hall at 8:30am :)
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Registration is open for a workshop on MPRAs (from sequence design to ML modeling) that we are organizing in Luebeck, Germany. Please join us in February! kircherlab.github.io/IGVF_wo…
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We mourn the loss of a great person. Our close collaborator Prof. Michael Speicher from MedUni Graz died suddenly last weekend. Michael was an outstanding scientist and good friend to all of us. Our thoughts are with his family, friends and lab members. medunigraz.at/news/detail/na…
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Martin Kircher retweeted
12 Sep 2023
AGD annual meeting is coming back this year on Oct 26-27, online and in Bonn, with the theme: Thinking beyond short read genomes #AGD2023 agdev.de/tagung2023.html

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🔈 Conference alert! #CRISPR & Beyond 2024! #CRISPR24 🗓️ 22-24 April 24 Join fellow biomedical researchers to explore methods to modulate the genome at scale, and what the future hold for #PrecisionMedicine! 📩Email us to for updates: conferences@wellcomeconnectingscience.org
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Amazing opening keynote in front of a full house. Actually not even everyone was allowed in the lecture hall. Congrats @jfkelso #ismbeccb2023
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Martin Kircher retweeted
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Came across this great review with beautiful figures on human-specific traits and how to study them, published last month by @Lab_Pollen, @genomeCraig, @KlkUmut and @GrayCampLab: nature.com/articles/s41576-0…

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Enjoyed writing this review on assays and resources for functional annotation of non-coding variants with my dear colleague @k_u_ludwig in Bonn: doi.org/10.1515/medgen-2022-…

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Congratulations to Prof Christian Gilissen (@gilissenc) for officially accepting his professorship at Radboud University in Nijmegen today!
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Martin Kircher retweeted
BREAKING NEWS: The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”
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kircherlab.github.io is recruiting 2 PostDocs (tinyurl.com/HLpostDoc. tinyurl.com/igvfHLpostDoc). Apply by Oct 10, 22. We are part of #IGVF, analyze reg. variant effects (MPRAs/CRISPR screens) and develop new comp. models & tools w/ @JShendure, @NadavAhituv, @malte_spielmann.

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Martin Kircher retweeted
We're now also recruiting clinical group leaders! Many great ones here already to collaborate with, and all the resources needed to accelerate your team's research.
💡 Applications are now open for our clinical group leader programme! We’re looking for innovative clinician scientists to join our faculty and establish a research group at the Crick. 📅Apply by 27 October 2022 #AcademicJobs | #ClinicalResearchjobs ow.ly/if5150KPZEq
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