Our POE summer student, Elizabeth, gave an outstanding presentation on our ongoing research into UBTF tandem duplications. It's been another fantastic summer in the lab, and we are grateful for your incredible effort. Wishing you all the best! 👏👏👏 @StJude@StJudeResearch
🎉 Klco Lab’s first graduate student Lauren Ezzell has successfully completed their candidacy exam! 🥳 Huge congratulations on this amazing achievement! Here's to more groundbreaking research and success ahead. 🌟 #AcademicAchievement#GradStudentLife
The Klco lab dinner was the perfect way to catch up and compare notes after a long day of learning from the best and brightest minds that #ASH23 has to offer!
Great dinner with current and former trainees of my mentor Tim Ley, who will receive the Stratton Medal tomorrow from @ASH_hematology#ASH2022. This field is all about mentor/mentee relationships and the communities they build.
#Cover: Samd9l mutant mice recapitulate phenotypes seen in pediatric myelodysplastic syndromes: buff.ly/3zoHdGm
Image: non-random chromosomal deletions of the mutant Samd9l locus in the mouse model; Credit: Virginia Valentine & Marcus Valentine
@KlcoLab@StJudeResearch
Relapse is common in children with acute myeloid leukemia and can be complicated to treat. Researchers at St. Jude found a mutation in AML that can be used to stratify high-risk patients and better guide treatment. bit.ly/3T05ARV@OncologyTimes@BCD_AACR@KlcoLab
Reanalysis of 553 pediatric #AML#WTS led to the identification of a new AML subtype with recurrent 9bp insertions in exon 3 of CBFB. The GEP of cases with CBFBins was similar to CBFB::MYH11 AML but had a more stem-like signature (BCL2L14, MEIS1, HOXA). doi.org/10.1182/blood.202201…