KOBEMicrollography!Structural biology of infection and immunity lab at UQ

Joined May 2022
17 Photos and videos
Pinned Tweet
Check out our recent preprint on the structure of a non C-JID TNL resistosome from flax. We are very proud of the persistence of Natsumi who got this long running project over the line and a congratulations to all involved. Check it out... doi.org/10.64898/2026.02.03.…
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If one TNL resistosome wasn't enough for you this weekend. Checkout another! Amazing work by all involved!
Coordinately submitting with @Kobe_Lab_ we're proud to report great collaboration with Selvaraj in @KamounLab to reveal basis for recognition of multiple effectors by the same immune receptor, to extend that recognition and to see the preactivation state biorxiv.org/content/10.64898…
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Structural basis of canonical TIR-NLR activation in plant innate immunity biorxiv.org/content/10.64898… #biorxiv_plants

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We wrote a focussed review on recent structural advancements in NLRs. It was a lot to cover we tried our best. We hope its enjoyable to experts in the field and useful to newcomers. Check it out: doi.org/10.1111/tpj.70702Dig…
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Kobe Lab retweeted
Little one’s first interstate conference done #ASBMB2025 Thank you to @ITSASBMB and local organisers @buffalo_berger @Kobe_Lab_ @ UQ for the support! Great conference great to be back!
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Kobe Lab retweeted
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5) doi.org/10.1101/2025.09.24.6…
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ASBMB2025!
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Excited to see our Arabidopsis TIRome paper published in PNAS. Have a read here doi.org/10.1073/pnas.2505893…. We hope this is the start of tuning TIR domains 😎
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Kobe Lab retweeted
Excited to be at #2025ISMPMI come see me at p16 Tuesday to hear more about TIR domains and an effector that inhibits flax TNLs
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4 Jun 2025
Great job at 3MT!!
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10 Jan 2025
Excited to share our work in @PNASNews . We report the cryoEM structures of both TRIF and TRAM uncovering the molecular basis of TRIF-mediated TLR3 and TLR4 signalling pathways. pnas.org/doi/10.1073/pnas.24…
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It has been a roller coaster year for me after experiencing extreme happiness and loss. Today I’m starting as a new PI @ANUChemistry. Very grateful to all my extended academic family @BiologyANU and all past and current mentors. Looking forward to forge new networks and collabs!
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This week we had the pleasure of hosting cryo-EM guru @OliBClarke who gave the @UQ_News cryo-EM community a fantastic cryo-EM data-processing workshop. Thank you Oli for sharing your tricks with us, @FarrahBlades for wrangling the Bunya supercomputer, and all who attended! 🔬
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Had a blast the last couple of days learning how to use our brand new Oryx8 crystallisation robot from @DougInstruments! First robot for the lab and first Oryx8 in Australia! 💎 #gulbaliinstitute #charlessturtresearch
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2024 @UQ_SCMB Structural Biology division retreat. Another fantastic three days of science, sun and fun!
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29 Oct 2024
And so it ends … 3 days of fantastic science and beautiful Freo weather #crystal35 #scanz. Thanks to everyone who joined us from Japan, Korea, India, South Africa, Singapore, UK and USA. And of course our amazing Australian and New Zealand structural science community!
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29 Oct 2024
All the rising stars of Crystal35 conference @Crystal_SCANZ 🎉💎🥳👏👍🥂 Congrats everyone
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29 Oct 2024
Exciting session at Crystal35 conference @Crystal_SCANZ with the “rising star awards” starting with @bj_charles @MonashBDI 🎉 congrats
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Kobe Lab retweeted
Congratulations to @JackKClegg for the 2024 SCANZ Mathieson Medal! @RACInational @UQ_SCMB 🥳
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