Director, Center for Regenerative Medicine of Boston University and Boston Medical Center @CReM_Boston. Physician-Scientist @BUPulmonary

Joined November 2011
151 Photos and videos
Darrell Kotton retweeted
Shame on the American Diabetes Association for calling the police on its own (‼️) Journal Editor & #ADA2026 presenters. If I were a donor I would withdraw my donation today. The board should issue an apology and resign now! Watch clip, see details below 👇🏼

12
40
142
43,422
Another great PhD thesis defense this week @CReM_Boston, this one from newly minted Dr. Julian Amirault of the @GMostoslavsky Lab, focused on the generation of human iPSC-derived CD4 T cells! Congrats, Dr. Amirault!
9
455
Darrell Kotton retweeted
So excited to share that the first paper from the Lung Disease Lab is now published in JCI Insight! I’m exceptionally grateful to all our collaborators and proud of the team, particularly Declan Turner for driving this work over the line! Read more here: lnkd.in/gTnRGiQJ
1
3
9
627
Our latest work from The KottonLab, just out now, focused on lung endothelium: "A chimeric human-mouse lung vascular model using induced pluripotent stem cells reveals insights into the pathogenesis of BMPR2-related pulmonary hypertension" biorxiv.org/content/10.64898…

2
3
16
617
Congrats to first author, Alex Holtz, MD, PhD, and co-authors @mjamal12 , Eric Austin, @PushpinderBawa, Mervin Yoder, and collaborators @CReM_Boston @The_BMC @BU_Tweets!
7
249
Our hands-on cell culture course @CReM_Boston for making lung out of iPSCs has kicked off and is running all week. Those smiles you see are from day 2: making endoderm, the first step to engineering lung epithelium! #itsthecells! #helpisontheway! @BU_Tweets @The_BMC
3
20
772
Darrell Kotton retweeted
Miriam O'Day, A1F Senior Policy Consultant, is representing the Alpha-1 Foundation at the 2026 NORD Rare Disease Scientific Symposium in Arlington, VA. This year's theme, "Advancing Innovation in Rare Disease Research," brings together a dynamic community of researchers, clinicians, industry leaders, and advocates to spark the conversations and connections that drive science forward. @RareDiseases
1
3
229
Darrell Kotton retweeted
Congratulations to Dr. Christine Reardon for receiving the Henry D. Chadwick Medal at MTS 2026! You are so loved by your colleagues, trainees, and patients. We thank you for your expertise in intensive care medicine, lung cancer, and neuromuscular respiratory disease.
1
191
Congrats to Dr. Andrew Wilson's Lab and MD/PhD student/first author, Carly Merritt on their new paper: "AT2-intrinsic Z-AAT expression drives conserved inflammatory and proteotoxic stress responses and predisposes to emphysema" biorxiv.org/content/10.64898…

3
11
776
Congratulations to Dr. Chris Reardon, this years Chadwick Medal awardee ⁦@MassThoracic⁩ 2026! Our once and always program director ⁦@The_BMC⁩ Pulmonary.
2
6
592
Great to be at the Mass Thoracic Society 2026 ⁦@MassThoracic⁩ annual meeting where MTS President Finn Hawkins is now kicking off the day!
1
4
17
1,132
Darrell Kotton retweeted
Today, Beam announced updated safety and efficacy data from the ongoing Phase 1/2 trial of BEAM-302 in alpha-1 antitrypsin deficiency (AATD) and the selection of 60 mg as the optimal biological dose to advance into pivotal development to support potential accelerated approval.
1
6
25
11,312
The Kotton Lab announces our latest biorxiv posting; a collaboration with the labs of Jessie Huang @hjhjess and Will Zacharias. "The chromatin remodeling complex PRC2 safeguards cell fate in alveolar epithelial type 2 cells" biorxiv.org/content/10.64898…

1
4
22
1,178
Darrell Kotton retweeted
Such a treat to tell our story of how discovering a previously unknown mechanism that controls IPF alveolar epithelial stem cell regeneration also enhances lung resilience against viral infection.
1
2
15
1,087
Darrell Kotton retweeted
We are back with the 4th edition of this fantastic lung meeting and what a busy day the #FusionLung26 crowd have had! Amazing talks, sharp questions, and lots of ideas to take back to the lab. We even made time for a quick snorkelling excursion along the beautiful Playa Mujeres coastline 🚤 🔬We are wrapping up this inspiring day with our first fantastic poster session and dinner!
3
3
6
766
Bidirectional fibrogenic cross-talk revealed in a human iPSC-derived epithelial-mesenchymal co-culture model of pulmonary fibrosis biorxiv.org/content/10.64898…

1
9
1,061