Bone and soft tissue, surgical and cytopathologist at University of Michigan | @UMichPath @UMichMedicine | T/RT not medical advice

Joined March 2024
35 Photos and videos
Stomp Out Sarcoma Fun Run/Walk is tomorrow at 9 AM in Hudson Mills MetroPark, Dexter, Michigan, for anyone interested in a running event! Walk-up registration begins at 8 AM. michiganmedicine.donordrive.…

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RT @KarenFritchieMD: Cleveland Clinic soft tissue pathology course starts in 7 days!! May 15-18. 150 digital cases. 15 sessions with staff.…
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Kyle Perry retweeted
Biphasic SS doesn't get better than this. IHC: AE1/AE3
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It’s gastric and spindled, but it’s not a GIST… Plexiform fibromyxoma is a benign tumor that presents as a multinodular intramural mass in the stomach. The nodules can be fibrous or myxoid and have a delicate capillary pattern. #BSTPath, #UmichPath, #BSTpathGoBlue
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The spindled morphology and plexiform architecture can sometimes cause these tumors to be mistaken for (SDH-deficient) GIST. Unlike GIST, these tumors are negative for CD117 and DOG1.
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Dealing with an unusual fibromyxoid spindle cell neoplasm (that is MUC4 negative)? Consider PLAG1! #BSTPath, #UmichPath, #BSTpathGoBlue
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Some nice papers (Fritchie and colleagues/ Chung and colleagues) further elaborating on this entity(ies)…. pubmed.ncbi.nlm.nih.gov/3309… pubmed.ncbi.nlm.nih.gov/3330…
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Special thanks to colleague at U of Michigan for allowing me to share this case!
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I would highly recommend this course for anyone (regardless of level of expertise) looking for a comprehensive/case-based experience with bone and soft tissue. Dr. Fritchie and colleagues at Cleveland Clinic are excellent teachers. clevelandclinicmeded.com/liv…

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ALK-positive histiocytosis of the breast is a rare tumor that can mimic other inflammatory neoplasms or processes, such as inflammatory myofibroblastic tumor, cellular spindled histiocytic pseudotumor (among others). #BSTPath, #UmichPath, #BSTpathGoBlue
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Interestingly, the cells in this case also showed staining for OCT2, which has historically been associated with other histiocytic-type proliferations, such as Rosai-Dorfman disease, some Langerhans cell histiocytosis, and juvenile xanthogranulomas.
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Nice article on ALK-positive histiocytosis of the breast: pubmed.ncbi.nlm.nih.gov/3282…
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Cellular spindled histiocytic pseudotumor (often of the breast) can sometimes be confused for inflammatory myofibroblastic tumor. The spindled cells exhibit irregular grooved nuclei which help suggest the tumor’s histiocytic nature. #BSTPath, #UmichPath, #BSTpathGoBlue
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Nice article by Sciallis, Chen and Folpe describing this entity. pubmed.ncbi.nlm.nih.gov/2298…
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Although not typically associated with a “round cell sarcoma” differential, solitary fibrous tumor can sometimes mimic small round cell type sarcomas such as Ewing sarcoma. #BSTPath, #UmichPath, #BSTpathGoBlue
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Nice article by Dermawan and colleagues on CD34-negative solitary fibrous tumors: pubmed.ncbi.nlm.nih.gov/3415…
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