6 May 2025
It’s gastric and spindled, but it’s not a GIST… Plexiform fibromyxoma is a benign tumor that presents as a multinodular intramural mass in the stomach. The nodules can be fibrous or myxoid and have a delicate capillary pattern. #BSTPath, #UmichPath, #BSTpathGoBlue
2
24
83
3,373
13 Apr 2025
Dealing with an unusual fibromyxoid spindle cell neoplasm (that is MUC4 negative)? Consider PLAG1! #BSTPath, #UmichPath, #BSTpathGoBlue
2
18
58
2,989
31 Mar 2025
ALK-positive histiocytosis of the breast is a rare tumor that can mimic other inflammatory neoplasms or processes, such as inflammatory myofibroblastic tumor, cellular spindled histiocytic pseudotumor (among others). #BSTPath, #UmichPath, #BSTpathGoBlue
1
32
56
2,844
12 Mar 2025
Although not typically associated with a “round cell sarcoma” differential, solitary fibrous tumor can sometimes mimic small round cell type sarcomas such as Ewing sarcoma. #BSTPath, #UmichPath, #BSTpathGoBlue
ALT Sheets of "round blue cells" in a solitary fibrous tumor
ALT Tumor cells in this SFT showed cytoplasmic vacuolizatoin.
2
21
83
3,663
23 Feb 2025
Dermatofibrosarcoma protuberans (particularly fibrosarcomatous DFSP) can occasionally be found to have a myoid type cell proliferation often associated with vessels (see arrows). #BSTPath, #UmichPath, #BSTpathGoBlue, #dermpath
2
23
83
3,873
8 Feb 2025
Desmoid fibromatosis can sometimes exhibit histologic features which overlap with nodular fasciitis, including focal areas of a more haphazard spindle cell arrangement. #BSTpath, #UMichPath, #BSTpathGoBlue
ALT Desmoid fibromatosis with haphazard spindle cell arrangement.
1
13
44
2,320
11 Jul 2024
Intravascular lobular capillary hemangioma can sometimes exhibit hobnail morphology or some nuclear atypia which can cause concern for a more aggressive vascular tumor. #BSTPath, #UmichPath, #BSTpathGoBlue, #dermpath
1
22
75
3,209
30 Jun 2024
Although sclerosing epithelioid fibrosarcoma is typically associated with epithelioid-like cells in the background of dense fibrosis, these tumors can occasionally exhibit higher grade nuclear features that mimic a “small cell” morphology.#BSTpath, #UMichPath, #BSTpathGoBlue
3
23
59
2,774
15 Jun 2024
Although desmoid fibromatosis can arise in the rectus abdominis muscle, endometriosis can also rarely produce a reactive fibroblastic reaction that mimics these desmoid tumors in the same location. #BSTpath, #UMichPath, #BSTpathGoBlue
2
21
57
3,649
25 May 2024
3
34
117
6,424
4 May 2024
Endoscopy is an unusual way to encounter a liposarcoma but occasionally happens. #BSTpath, #UMichPath, #BSTpathGoBlue, #GIpath
4
47
124
8,581
21 Apr 2024
An (acute) obsession with inflammatory well-differentiated liposarcoma….
#BSTpath, #UmichPath, #BSTpathGoBlue
2
15
57
4,214
13 Apr 2024
I know there is a subcutaneous mass, but where are all the cells? #BSTpath, #UMichPath,#BSTpathGoBlue, #dermpath
ALT Amorphous eosinophilic material with scattered vessels.
ALT Eosinophilic material with foreign body giant cells.
ALT Massive foreign body giant cell with eosinophilic material wrapping around vessels.
ALT Focal area of chronic inflammation.
2
20
61
7,681
7 Apr 2024
5
53
135
16,695
30 Mar 2024
If everyone suspects metastatic tumor, why am I seeing giant cells? #BSTpath, #UMichPath, #BSTpathGoBlue
3
23
77
10,430
23 Mar 2024
GLI1-altered mesenchymal tumor is a "great mimicker" that can morphologically/immunohistochemically imitate many other entities. The presence of a lobular tumor with round to epithelioid cells and nests of tumor cells protruding onto vascular spaces can be a helpful hint for further assessment. #BSTpath, #UMichpath, #BSTpathGoBlue
Great review article -pubmed.ncbi.nlm.nih.gov/3827…
Great soft tissue edition of surg path clinics -
surgpath.theclinics.com/issu…
ALT Gli1-altered mesenchymal tumor with lobulated (and cystic) architecture.
ALT Lobulated tumor nests. The tumor pushes against a slit like vascular space at the periphery (arrow).
ALT Tumor with both sheet-like and nested/reticular (shown) architecture.
ALT Gli1 in-situ hybridization is positive
2
37
81
6,447