Congrats to Lea and the team of @LLM_Lab @InstitutImagine

I am pleased to announce my thesis publication in @JCI_insight on Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralisation in mice buff.ly/3XzexFv . Thanks to my amazing mentors and colleagues @LLM_Lab

#Cover: Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice: buff.ly/3XzexFv Image: μCT image of the fifth lumbar vertebra of a 10-week-old mouse. @LLM_Lab @Inserm #BoneBiology #Genetics

Encore l'@InstitutImagine à la société américaine de génétique Los Angeles 2022 : communication sélectionnée de Laurence Legeai-Mallet @LLM_Lab sur les essais pré cliniques dans l’hypochondroplasie, avec QED Therapeutics ! #ASHG22

Always fun to be around the Frenchies … Having a nice time at the meeting

project partners are @TomVanAgtmael @TheRuggieroLab @aforlino @MD_Briggs @FZaucke @KasiaPirog1 @BonaldoLab #evercyte #medetia @LLM_Lab @LifeTecGroup

Cornille et al @LLM_Lab show that FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model bit.ly/3HTBVns From our #Neuroimmunology & #Neurodegeneration collection: bit.ly/38Ermcv #KSNeuroImmune22 #KSNeuroDegen22

Félicitations à l équipe Nantaise .. édition 2022 outstanding

Maxence Cornille, Stéphanie Moriceau, Laurence Legeai-Mallet @LLM_Lab and colleagues suggest that modulation of the FGFR3 signaling pathway might be of value for treating the neurological and cognitive impairments observed in craniosynostosis. bit.ly/3HTBVns

Happy to finally share our study on « Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia » now published rdcu.be/cGaie #BoneRes #achondroplasia #epicatechin #FGFR3 #primarycilia @NaturePortfolio @SpringerNature

Looking at a zebrafish head to see what’s happening in skull sutures. It's the objective of our starfish team composed of Dr Emilie Dambroise, Rachel Pereur (PhD student) and Yvan Marc (engineer) doi.org/10.1002/jbmr.4042

#LesRDVdelaRecherche🔬 Notre 1er RDV de la recherche de l'année c'est mardi pro avec les Pr Valérie Cormier-Daire & Laurence Legeai-Mallet pour une présentation sur "Un nouveau traitement pour #achondroplasie". #maladiesrares 👀 Vite inscrivez-vous ➡ forms.gle/uuM1cF2szCdqgWsQ6

For whom interested in the association of BMN111 and LB100 in achondroplasia treatment. See our last publication in collaboration with Dr. Laurinda Jaffe doi.org/10.1172/jci.insight.…. #jciinsight #achondroplasia #Bones #cartilage @InstitutImagine @Uconn

Hello, We are new on tweeter, we are a bone and cartilage research lab with a focus on FGFR3. Now, connected to the scientific community and we will be delighted to share exciting science. @InstitutImagine #ECTS #ASBMR