PhD student. Working on epigenetic, embryonic development and FASD. Outdoor lover and chocolate addicted.

Joined February 2017
17 Photos and videos
Lisa-Marie Legault retweeted
Thank you @CR_CHUSJ for showcasing our lab's work, led by @LM_Legault , on the impact of early embryonic alcohol exposure on the placenta. @CIHR_IRSC @FRQS1 #epigenetics
Exposition de l’embryon à l’alcool en tout début de grossesse : des effets épigénétiques décelables dans le placenta selon une nouvelle étude par @McGraw_Lab et coll. @CR_CHUSJ tinyurl.com/4kx9vs3e
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Latest paper is now out! This one might be even more special as it is my last PhD paper. Thanks to all the co-authors & @McGraw_Lab thanks for everything. I was lucky to spend my years as a graduate student in such a stimulating environment, with an amazing team and involved PI.
Paper alert! @LM_Legault et. al show that preimplantation alcohol exposure alters the #DNAmethylation and transcriptomic profiles in mouse placentas in a sex-specific manner, with DNA methylation being a robust predictive signature. bit.ly/4egTNcZ @CR_CHUSJ #FASD
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Amazing project led by @eli__elder Look at these figures 👌🏻
What is the long-term impact of loss of sustained DNA methylation maintenance by DNMT1 for molecular and cellular integrity of mouse embryonic stem cells? Thrilled to share the lab’s newest preprint bit.ly/3WDALr5 Amazing effort from @eli__elder and team! 🧵1/11
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Lisa-Marie Legault retweeted
And that's a wrap on #CanEpi23! Thank you to everyone who attended and all of the sponsors for their continued support of our meeting. We've enjoyed seeing all of the amazing science and wonderful interactions that have taken place over the last 3 days. See you all in 2024!
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Lisa-Marie Legault retweeted
Explore our latest @Preprints_org review aiming to highlight O-GlcNAcylation's central role as an epigenetic mark, focusing on histone modifications. Collaboration with Thomas Dupas (new postdoc in our lab) and Prof. Benjamin Lauzier (@NantesUniv France ) preprints.org/manuscript/202…

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Lisa-Marie Legault retweeted
Our News and Views ―Inheritance of epigenetic DNA marks studied in new mouse model― of the Takahashi et al. Cell 2023 paper on the Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice. Fun collaboration with @KimminsSarah nature.com/articles/d41586-0…

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Lisa-Marie Legault retweeted
Happy to share our study in @FASEBorg ! Using a mouse model of pre-implantation alcohol exposure, we show that a maternal enriched diet for methyl-donor mitigates the negative impacts of alcohol exposure. #FASD bit.ly/3LcatGS

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Poster tonight at #CanEpi22 Thanks to the @CEEHRC new childcare subsidy initiative for giving me the opportunity to present at the meeting while be present for my little human! Grateful and lucky to evolve in such an inclusive field!
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Awesome view after great science at #DOHaD2022 in Vancouver! First in person meeting since early 2020 and first one with my little human!
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Lisa-Marie Legault retweeted
Don't miss out! The deadline for both early bird registration and travel award applications is midnight pacific time!! The 8th Annual Conference on Epigenetics: ceehrc.ca/2022/ Travel Awards for Trainees: thisisepigenetics.ca/for-sci… #CanEpi22 #IHEC2022 #ThisIsEpigenetics

ALT Work Stressed GIF

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Lisa-Marie Legault retweeted
En ce mois de la sensibilisation au trouble du spectre d'alcoolisation fœtale, une nouvelle étude du professeur @McGraw_Lab met en garde contre une forte consommation d’alcool dès la 1re semaine de grossesse. ➡️ bit.ly/39lg2P3 #Epigenetics #DNAmethylation #FASD
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So happy about that paper!!
Happy to share the published open access version (with added data) of our pre-print paper from @LM_Legault and team! Find below tread on main results. clinicalepigeneticsjournal.b…
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Lisa-Marie Legault retweeted
Check out our updated version of the paper!
Very excited to share our new work (@LM_Legault et al.) Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain #FASD #Epigenetics #DNAmethylation 1/ biorxiv.org/content/10.1101/…
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Lisa-Marie Legault retweeted
Today, we launch a new initiative: This Is Epigenetics!—an effort to support Canadian epigenetic researchers and engage people across the country with this rapidly evolving and exciting field of study! Check it out: thisisepigenetics.ca #epigenetics #epigenomics #scicomm #kt
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Lisa-Marie Legault retweeted
Paper is out! See the final version of our #preprint now published in @EpigeneticsJ : Developmental genome-wide DNA methylation asymmetry between mouse placenta and embryo. Thanks again to reviewers for thoughtful suggestions! tandfonline.com/doi/full/10.…
Developmental Genome-Wide DNA Methylation Asymmetry Between Mouse Placenta and Embryo biorxiv.org/cgi/content/shor… #bioRxiv
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Lisa-Marie Legault retweeted
It’s International Day of Women and Girls in Science! To my sisters in science, know you have a champion and an ally. Let’s inspire the next generation to discover. Because more than ever, the world needs science; and science needs women. #WomenInScience
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What an amazing meeting once again!!
From your registration desk team; we wish all of our #CanEpi19 and #IHEC2019 attendees a safe journey home. Thank you for sharing your wonderful science & engaging with our KT initiative. See you in Esterel Resort next year for #CanEpi20
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