AD/PD - Advances in Science & Therapy

AD/PD - Advances in Science & Therapy

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Leonard Pieperhoff retweeted

@adpdnet

1 Apr 2025

Polygenic risk for AD influences WM integrity both directly and via AD pathology-dependent mechanisms, suggesting that distinct biological processes are activated by AD pathology to drive white matter alterations. More on WHITE MATTER ALTERATIONS AND MRI in Hall A #ADPD2025

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Luigi Lorenzini

Leonard Pieperhoff retweeted

Luigi Lorenzini @LuigiLorenzini1

25 May 2024

A nice work from our team finally out!🧠 Led by Mario Tranfa, we used multimodel selection and latent variable modelling to show the differential impact of vascular and AD-related factors on white matter microstructure. pubmed.ncbi.nlm.nih.gov/3875…

Alzheimer's Disease and Small Vessel Disease Differentially Affect White Matter Microstructure -...

Our results suggest that AD pathology and cSVD exert independent and spatially different effects on WM microstructure, supporting the role of DTI in disease monitoring and suggesting independent...

pubmed.ncbi.nlm.nih.gov

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