The Alper Lab strives to perform high-quality, reproducible research to make new tools for synthetic biology and metabolic engineering.

Joined August 2020
24 Photos and videos
The Alper Lab retweeted
12 Sep 2025
Join McKetta Department of Chemical Engineering as an assistant professor, tenure-track, starting Fall 2026. Ideal candidates have research connections to biotechnology and/or materials engineering. Learn more, and apply: bit.ly/ChE_AP2025.
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A great upcoming conference to attend.
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In his lecture "Engineering Biology to Develop a Taste for Waste" at #AIChEAnnual October 29 in San Diego, Hal Alper will address how #metabolic engineering and synthetic biology are improving how we deal with waste. bit.ly/3XD5nt5 @LabAlper #synbio

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The Alper Lab retweeted
In an effort to re-circularize plastic waste in upcycled technologies, @LabAlper of @UTAustin will screen 1000s of untested enzymes that can degrade common plastics. @TexasChE jgi.doe.gov/announcement-csp…
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New robust (growth-phase and scale-independent) promoters for S. cerevisiae doi.org/10.1016/j.synbio.202…

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Recently we reported on a co-culture system enabled by Y. lipolytica to produce apigenin and isovitexin. doi.org/10.1016/j.ymben.2024…

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We are thrilled to be working with @bit_Biome on a collaboration to find new plastic degrading enzymes and microbes! @soichirotsuda bitbiome.bio/news/news-press…

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The Alper Lab retweeted
A sustainable future is biological. How can we engineer biology to make what we need? We worked with @LabAlper @jgi to explore accelerating biological design with flux enhanced cell-free systems. #syntheticbiology doi.org/10.1016/j.ymben.2023…

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Excited to see our collaboration with @MichaelCJewett @JGI published. Here we combine metabolic engineering with cell-free biology to produce pre-optimized, flux enhanced cell extracts for rapid prototyping of pathways doi.org/10.1016/j.ymben.2023…

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Our latest @NatureComms paper features a tripartite consortium for producing phenylpropanoids (including eugenol). Modular consortia can overcome enzyme promiscuity limitations. These consortia also work in Engineered Living Materials. @NelsonLabUW @NSF doi.org/10.1038/s41467-023-4…

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The Alper Lab retweeted
13 May 2023
Three university teams and an industry performer will take initial steps to lessen risks associated with biomanufacturing capabilities in resource-limited environments, including space, as part of the DARPA B-SURE program #UF #UTAustin #WUSTL #Space_Tango ow.ly/Cwi450OmTrj
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The Alper Lab retweeted
Our lab has been collaborating with the @LabAlper, @NelsonLabUW, and @AyokunleOlan among others to make engineered living materials! Imagine a building material that can photosynthesize, make chemicals, and repair itself! bit.ly/41Atlou
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We're excited to announce the publication of our most recent article that utilizes microfluidic droplet screening to identify differential itaconic acid production phenotypes in yeast. Read it here: doi.org/10.1039/D3LC00020F

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The Alper Lab retweeted
18 Mar 2023
Three university teams will explore and take initial steps to mitigate risks associated with manufacturing capabilities that rely on biological processes in space as part of the DARPA B-SURE program #UF #UTAustin #WUSTL ow.ly/vLLE50NkweF
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The Alper Lab retweeted
Excellent work led by @gokcealtn in collaboration with @LabAlper!
These nuts and bolts are made of a hydrogel that acts as a scaffold for living cells. Those cells can change the stiffness of the material via continuous L-DOPA production. 👉 ow.ly/JM5m50NkbS0
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