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Fame Lab @LabFame

basic & translational research • brain development • CSF-based signaling & choroid plexus • @StanfordMed • Dept. of Neurosurgery @StanfordNsurg • @ScienceDame

Joined July 2022
  • Tweets 228
  • Following 161
  • Followers 433
64 Photos and videos
Congratulations to Sarah on passing her qualifying exam! A new PhD candidate is minted!
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Fame Lab retweeted
Kaltschmidt-Lab@kaltschmidt_lab
Jan 13
So grateful for everyone who has supported me on this journey. Special thanks to all my current and former trainees!
Stanford Neurosurgery@StanfordNsurg
Jan 9
Congratulations to Julia Kaltschmidt, PhD (@kaltschmidt_lab), on her promotion to Professor of Neurosurgery! Dr. Kaltschmidt!
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Fame Lab retweeted
Stanford Neurosurgery@StanfordNsurg
Jan 9
Congratulations to Julia Kaltschmidt, PhD (@kaltschmidt_lab), on her promotion to Professor of Neurosurgery! Dr. Kaltschmidt!
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📃Preprint alert @biorxivpreprint . Does your 2026 involve ICV injections of AAVs 🧠? If so, this study led by Luke in the lab is for you. biorxiv.org/content/10.64898…
Representative 3D reconstructions of brain ventricles from control and high-dose AAV2/5-injected pups at 2, 5, and 7 days post-injection (P2.5, P5.5, P7.5). Quantification of total ventricular volume across time points. (n = 3 per condition)

ALT Representative 3D reconstructions of brain ventricles from control and high-dose AAV2/5-injected pups at 2, 5, and 7 days post-injection (P2.5, P5.5, P7.5). Quantification of total ventricular volume across time points. (n = 3 per condition)

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Dose is key🗝️. Higher doses of AAV (1uL of 4 x 10^12 GC/mL) consistently induced ventriculomegaly and permissive tropism in neonates, while moderate doses (1uL of 1 x 10^12 GC/mL) didn't. Study led by Luke Liu, with co-authors Ania Noguera, Ryan Humphries, and Blake Zhou.
Representative coronal sections at the level of the posterior anterior commissure (pAC; dashed outline) showing lateral ventricle morphology in P7.5 brains following P0.5 ICV injections.

ALT Representative coronal sections at the level of the posterior anterior commissure (pAC; dashed outline) showing lateral ventricle morphology in P7.5 brains following P0.5 ICV injections.

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Fame Lab@LabFame
15 Dec 2025
Such a joy to celebrate with this group! Happy holidays from our lab to yours! 🧠☃️🥼🧪
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Fame Lab@LabFame
18 Nov 2025
Go with the Flow🧠💦 at #SfN25. Meet the speakers of Nano 040 today (Tuesday 11/18) at 1pm in room 24A. #NeuroTwitter #SciTwitter @SfNtweets
Nano 040 today (Tuesday 11/18) at 1pm in room 24A. Neil Dani, Vanderbilt Laura Pellegrini, KCL Huixin Xu, BCH Luke Liu, Stanford Cameron Sadegh, UC Davis Ed Monuki, UC Irvine Haley Masters, Vanderbilt Catie Profaci, Scripps Agnes Luo, U of Cincinnati Deidre Jansson, U of Washington Ryann Fame, Stanford

ALT Nano 040 today (Tuesday 11/18) at 1pm in room 24A. Neil Dani, Vanderbilt Laura Pellegrini, KCL Huixin Xu, BCH Luke Liu, Stanford Cameron Sadegh, UC Davis Ed Monuki, UC Irvine Haley Masters, Vanderbilt Catie Profaci, Scripps Agnes Luo, U of Cincinnati Deidre Jansson, U of Washington Ryann Fame, Stanford
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Fame Lab retweeted
Nature Biotechnology
@NatureBiotech
11 Nov 2025
Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models - @StanfordRad go.nature.com/4nO5s71
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“We’re making a helmet people can wear that delivers ultrasound to the brain, and we plan to initiate clinical testing of this protocol in the next few months,” said Raag Airan. With Knight Initiative support, his lab plans to test it on people soon. 🔗brainresilience.stanford.edu…
Raag Airan, Matine Azadian, Payton Martinez and Yun Xiang in the lab. Azadian is holding a version of their ultrasound apparatus designed for humans.

ALT Raag Airan, Matine Azadian, Payton Martinez and Yun Xiang in the lab. Azadian is holding a version of their ultrasound apparatus designed for humans.
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Fame Lab@LabFame
10 Nov 2025
Will you be at @SfNtweets #SfN25? Yes? Us too! Come see the Fame lab!
Blake Zhou Sunday, 11/16, 8am-12pm. Presentation Number: PSTR053.24/ A22 Location/Room: A22 SDCC Halls B-H Arjun Rajan Sunday, 11/16, 1pm-5pm. Presentation Number: PSTR102.04/A40 Location/Room: A40 SDCC Halls B-H Luke Liu Ryann Fame Tuesday 11/18, 1pm-3:45pm. Session Number: Nanosymposium NANO040 Session Title: Choroid Plexus and CSF Biology Location/Room: SDCC Rm 24A Nano040.04; Nano040

ALT Blake Zhou Sunday, 11/16, 8am-12pm. Presentation Number: PSTR053.24/ A22 Location/Room: A22 SDCC Halls B-H Arjun Rajan Sunday, 11/16, 1pm-5pm. Presentation Number: PSTR102.04/A40 Location/Room: A40 SDCC Halls B-H Luke Liu Ryann Fame Tuesday 11/18, 1pm-3:45pm. Session Number: Nanosymposium NANO040 Session Title: Choroid Plexus and CSF Biology Location/Room: SDCC Rm 24A Nano040.04; Nano040

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Fame Lab@LabFame
7 Nov 2025
The Fame Lab is 3 years old this week! Time flies with this fantastic group of scientists!
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Fame Lab@LabFame
3 Oct 2025
We are thrilled to receive support from the @StanfordBrain Wu Tsai Institute to start a new collaboration with @HeilshornSarah and her team!
Wu Tsai Neurosciences Institute@StanfordBrain
2 Oct 2025
Congrats to the Seed Grant awardees! Projects include efforts to develop new tools for delivering drugs to the brain; study the role of neuropeptide molecules in pain & brain signaling; and probe the links between genetics, inflammation, & Alzheimer’s. 🔗neuroscience.stanford.edu/ne…
2025 Seed Grant awardees (10 awardees across 5 projects)

ALT 2025 Seed Grant awardees (10 awardees across 5 projects)
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Fame Lab@LabFame
10 Sep 2025
Third Annual Dish Dish Dish to enjoy each other's company and celebrate a love of science! 📡 🗣️ 🍽️ @StanfordNsurg #ScienceMatters
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Fame Lab@LabFame
7 Aug 2025
Today, we celebrate Ania Noguera's time in the lab. On her last day with us, we are so excited about her transition to @UCBerkeley - but will miss her expertise here! 🧠
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Fame Lab retweeted
Nature Neuroscience
@NatureNeuro
7 Jul 2025
Our July issue is now live! nature.com/neuro/volumes/28/…
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Fame Lab@LabFame
2 Jul 2025
Stepping out of the lab to enjoy some artistic pursuits!
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Fame Lab@LabFame
5 Jun 2025
Molecular Hallmarks of Hydrocephalus @ScienceTM is out today. Grateful to work under leadership of @andrewthale3 @ScienceDame @KahleKristopher with other top-notch collaborators including @LabFame members Arjun Rajan and Blake Zhou! science.org/doi/10.1126/scit…
https://www.science.org/doi/10.1126/scitranslmed.adq1810

ALT https://www.science.org/doi/10.1126/scitranslmed.adq1810
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Fame Lab@LabFame
26 May 2025
How does the brain change during the day🌞🌛? Can this inform treatments? Learn more in a new review from the lab 'Harnessing the #circadian nature of the choroid plexus and cerebrospinal fluid' npj Biological Timing & Sleep | #Nature @Nature_NPJ nature.com/articles/s44323-0…
Fig. 1 | Components of the cerebrospinal fluid (CSF) system change across timeof day. A The major components of the CSF system include CSF, choroid plexus, andcircumventricular organs. These systems change their properties across time of day,including those listed below each component. B Multiple inputs affect the CSFsystem across time of day.

ALT Fig. 1 | Components of the cerebrospinal fluid (CSF) system change across timeof day. A The major components of the CSF system include CSF, choroid plexus, andcircumventricular organs. These systems change their properties across time of day,including those listed below each component. B Multiple inputs affect the CSFsystem across time of day.

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Fame Lab@LabFame
26 May 2025
Many thanks to the editors of @Nature_NPJ Biological Timing and Sleep for treating this important topic and for the collegial and scholarly reviewers who reviewed this article. rdcu.be/enKEO

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Fame Lab retweeted
Hydrocephalus Assoc.
@HydroAssoc
23 May 2025
🎹 Billy Joel courageously shared his diagnosis of normal pressure #hydrocephalus (#NPH). HA sends strength to him and his family. His openness brings vital awareness to this condition. 💙 #HydrocephalusAwareness #BillyJoel hydroassoc.org/billy-joels-d…

Billy Joel’s Surprising Diagnosis of Normal Pressure Hydrocephalus

The Hydrocephalus Association extends its heartfelt support to Billy Joel and his family following his recent diagnosis of normal pressure hydrocephalus (NPH).

hydroassoc.org
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