Natural Products, Biosynthesis, Enzymology, Genome Mining, Bioengineering

Joined August 2018
49 Photos and videos
The #BJOC thematic issue on Young investigators in natural products chemistry, biosynthesis, and enzymology is now complete! 31 contributions from young investigators around the world! Check it out! @BeilsteinInst beilstein-journals.org/bjoc/…
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More exciting biosynthetic work on bacterial #eunicellane #diterpenoids out of the @Helfrich_lab!
Our study in ACS Chem Biol reveals a unique eunicellane pathway featuring a reductase fused with a terpene cyclase, a P450 split into 3 fragments and a hypothetical protein with dual isomerase and oxygenase functions! pubs.acs.org/doi/full/10.102…
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Rudolf Lab retweeted
Out now in @Chem_CP , we collaborate with @piel_lab to discover a prenyltransferase terpene cyclase fusion enzyme that modifies Trp residues in RiPPs to yield complex steroid-like scaffolds! Congrats to @HubrichFlorian, @sanathrajkk0 for leading this!🎉authors.elsevier.com/c/1jjdi…
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Bacteria are talented producers of #diterpenes. We screened 334 terpene synthases: doi.org/10.26434/chemrxiv-20…. New skeletons, new stereoisomers, terpenes known in other organisms but new to bacteria. A massive team effort led by Xiuting Wei and Wenbo Ning! @UFChemistry
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13 Aug 2024
A shout out to one of the reviewers for taking the time to look at all of our NMRs and catching an NMR mis-assignment. Thank you! 🙏
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18 Jul 2024
Excited to see these photos from #ICNPR2024! Congrats to Daniel @dicenhour91 and Diana Łomowska-Keehner for their wonderful presentations on bacterial #terpenes. Thanks for representing us in Poland at #ICNPR2024! @pharmacognosy
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18 Jul 2024
Many thanks to @pharmacognosy and @UF_CLAS for supporting Diana with travel awards!
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18 Jul 2024
Our former postdoc Prof. Baofu Xu and his group just published in @NatureComms on the microeunicellol-type bacterial eunicellane #diterpenoids. Check it out here: rdcu.be/dOdoS #proudPI Congrats @Baofu_Xu!

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Rudolf Lab retweeted
24 Jun 2024
We are looking for a postdoc!
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19 Jun 2024
A bit late, but wanted to share our newest paper in #BJOC on eunicellane #diterpene chemistry. @lizining666 Another fun collaboration with @TantilloLab @LoesgenLab! beilstein-journals.org/bjoc/…
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Daniel @dicenhour91 and Diana Łomowska-Keehner representing @rudolflab at @AmerChemSociety #FAME2024! Congrats to both you of for 2 great presentations!
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Rudolf Lab retweeted
3 Jun 2024
We are excited to finally publish the unprecedented biosynthetic origins of enediyne natural products: iodinated polyynes! This transformative discovery is a huge milestone for these clinical antitumor antibiotics. @Kalkreuter @guichun98 @nchembio nature.com/articles/s41589-0…
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Rudolf Lab retweeted
15 May 2024
Early Announcement! simbhq.org/np/ Together with Brad @BradMoore_SIO, Jaclyn @JMWinterlab, and Alessandra @EustaquioLab, We look forward to welcoming you to the 2025 @SIMB_Microbio Natural Product meeting at San Diego! Keynote speaker Prof. Jennifer Doudna! @doudna_lab

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14 May 2024
We are hiring an NIH-funded postdoc! Looking for a highly motivated researcher with a strong background in natural product isolation and structural characterization for #terpene NP discovery, #biosynthesis, #enzymology. Please RT! @UFChemistry explore.jobs.ufl.edu/en-us/j…

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Researchers @Fudan University 🇨🇳 focus on #chemoenzymatic synthesis of macrocyclic peptides and polyketides via #thioesterase-catalyzed #macrocyclization. #biosynthesis ➡️ beilstein-journals.org/bjoc/… Thanks for guest editing @LabRudolf, @barra_lena and Takayoshi Awakawa! 💎🔓 #BJOC
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Rudolf Lab retweeted
Ever wonder what you might want to know about going to your first conference? How to navigate interacting at a scientific meeting? Check this out!! @pharmacognosy @youinthelab @ABRCMS
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Ready to celebrate @tyler_alsup_ at @UF_CLAS PhD ceremony! @UFChemistry #ProudPI
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Here's the action shot! @tyler_alsup_
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