Joined August 2020
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really nice work. Glycogen plays an important regulatory role in many cells.
Neuronal glycogen powers anticipatory brain responses to food dlvr.it/TSlMGK
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Behind the scenes with first author Churaibhon Wisessaowapak as she prepares Western Blot samples.
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How does caloric restriction reduce energy expenditure while preserving energy storage? doi.org/10.1172/jci.insight.… Alan R. Saltiel @LabSaltiel & team @UCSanDiego show TBK1 acts as a brake on fat burning during fasting—and the combination of a TBK1 inhibitor and an AMPK activator reverses obesity and improves #MetabolicHealth in mice. The figure: Combined TBK1 inhibition and AMPK activation improve metabolic health in obese mice.
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Tomorrow (5/12), join us for the 2026 Saltiel Life Sciences Symposium: Decoding #GLP1s. View the full schedule, including a poster session featuring U-M research: lsi.umich.edu/events/2026-05…
Join us May 12 for the 2026 Saltiel Life Sciences Syposium: Decoding GLP-1s! This full-day event will explore the fundamental cellular mechanisms behind the new generation of hashtag#GLP1 therapeutics, as well as ongoing efforts to improve them. Speakers include @AmberAlhadeff, @DanielJDrucker, @TimoMueller_IDO, Martin Myers, @tunepers , @seeleyrj and @thewilliamslab
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Dr. Irfan Lodhi and collaborators identified a pathway that regulates how the body breaks down fat during metabolic stress, including severe illness and cachexia, revealing insight into how stable fat stores are mobilized under stress conditions. bit.ly/3OVi7d7
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will be great to get back to Ann Arbor for this meeting.
Join us May 12 for the 2026 Saltiel Life Sciences Syposium: Decoding GLP-1s! This full-day event will explore the fundamental cellular mechanisms behind the new generation of hashtag#GLP1 therapeutics, as well as ongoing efforts to improve them. Speakers include @AmberAlhadeff, @DanielJDrucker, @TimoMueller_IDO, Martin Myers, @tunepers , @seeleyrj and @thewilliamslab
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Sad news. Such a sweet guy. Always positive and supportive, a serious scholar and terrific leader. He'll be missed.
A gentleman and scholar, leader in #islet biology, Editor of @Diabetes_ADA Professor Gordon Weir @Harvard @AmDiabetesAssn @JoslinDiabetes legacy.com/us/obituaries/nam… March 27 2026
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With great sadness I report the passing of my scientific mentor Jesse Roth at age 91. Jesse was a brilliant & innovative scientist who led the field of membrane receptor biology from NIH diabetes branch. A small part of that family tree is shown. May his memory be a blessing.
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Kvelling again about a former trainee. Xiao-wei Chen in another major breakthrough in Nature. Beautiful paper.
Feb 26
Nature research paper: CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis go.nature.com/4rzQTXg
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Very proud of my former trainee Shannon Reilly @ShannonReilly5. An exciting new look at thermogenesis.
Fatty acids promote uncoupled respiration via ATP/ADP carriers in white adipocytes dlvr.it/TR6ggv
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Feb 14
Meet the sixteen ASBMB members who were recognized for exceptional service and scientific impact across research, education, mentorship, outreach and leadership! asbmb.org/asbmb-today/people… #ASBMBMemberNews #Biochemistry #MolecularBiology #ASBMBFellows
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Jan 23
Meet the 2026 ASBMB Fellows Sixteen members were recognized for exceptional service and scientific impact across research, education, mentorship, outreach and leadership. Join us in celebrating them at #ASBMB26! ➡️ Learn more about the 2026 fellows: asbmb.org/asbmb-today/people….
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the next chapter in our investigation into how glycogen metabolism is regulated in fat cells; terrific work from Haipeng Fu and our collaborators.
16 Dec 2025
Happy to share our paper is now published in @NatureComms. This work studies transcriptional regulation of glycogen metabolism genes in adipocytes. Grateful to my mentor @LabSaltiel and all collaborators for their guidance and support. nature.com/articles/s41467-0…
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16 Dec 2025
Happy to share our paper is now published in @NatureComms. This work studies transcriptional regulation of glycogen metabolism genes in adipocytes. Grateful to my mentor @LabSaltiel and all collaborators for their guidance and support. nature.com/articles/s41467-0…
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The longer version of my tribute to Pedro Cuatrecasas.
#NASmember Pedro Cuatrecasas devoted himself to improving human health, overseeing the development of 40 new drugs across his career. Read about his work as a scientific innovator and leader in pharmaceutical discovery in a new memoir: ow.ly/A1vW50XAmEw #MemoirMonday
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Congrats to Postdoc Danny Son and all of our colleagues and collaborators on this paper.
Neutrophil-derived IL-1β preserves lipid stores during metabolic stress, highlighting a physiological function of innate immune cells in limiting lipid loss and maintaining energy homeostasis @Nature @UCSDMedSchool @LabSaltiel nature.com/articles/s41586-0…
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Obituary: Pedro Cuatrecasas (1936–2025) go.nature.com/4pHtmCC
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