Professor @UCSF. Retinal cell biology, imaging, age-related macular degeneration, sight saving therapies.

Joined October 2011
12 Photos and videos
Pinned Tweet
New paper from our lab in @CurrentBiology identifies a novel mechanism of waste management in the retina. In this @NatEyeInstitute funded research, we discovered that the RPE practices intelligent altruism – something we can all learn from! sciencedirect.com/science/ar…

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What do you need to do? • Check out the program: keystonesymposia.org/confere… • Register to attend! • Submit an abstract to be selected either for a short talk or a poster! • Spread the word!!!
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Keynote by Botond Roska. Featured speakers @GMalekLab @ChoroidLab @Drusen_Lengyel @ProfRobynGuymer Emily Chew from @NatEyeInstitute @anneke_denh James Handa from @HopkinsMedicine Valeria Canto-Soler from @CUAnschutz Florian Sennlaub from @InstVisionParis
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New paper from our lab in @CurrentBiology identifies a novel mechanism of waste management in the retina. In this @NatEyeInstitute funded research, we discovered that the RPE practices intelligent altruism – something we can all learn from! sciencedirect.com/science/ar…

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Using powerful live imaging and mouse models, we identify hierarchical roles for optineurin in outer segment phagocytosis, phagosome maturation, and lysosome biogenesis. These are unaffected in AMD, suggesting that the RPE prioritizes removal of phagocytosed cargo in disease.
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Independent regulation of debris removal mechanisms safeguards the metabolic fitness of the retina. Shout out to supremely talented senior postdoc Li Xuan Tan for leading this study and thankful for funding support from @NatEyeInstitute, @_BrightFocus, and @RPB_org.
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It's been an amazing few months for the immensely talented young scientists in our group! In the spring, we welcomed Valencia Fernandes from NIPER Hyderabad and Cheng an from Tohoku University as our new postdoctoral associates.
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Connor Tseng won the SURF Rose Hill Fellowship, Colin Germer a #RD2023 travel award, Nilsa La Cunza the UCSF Achievement Rewards for College Scientists award, and Sydney Williams the prestigious UCSF Chancellor Award for Dr. MLK, Jr. Leadership.
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And in just a few weeks, senior postdoc Li Xuan Tan is heading off to set up her own independent research group. #ProudMentor
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So proud to be a part of the @_BrightFocus family!
On this #InternationalWomensDay, we are proud that 44% of our funded researchers are women, especially given that women make up less than 30% of the world's scientists. We are grateful and honored to have these exceptional women on our #mindsightcure team.
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What a great session on “nuclear control of RPE cell fate” - amazing speakers and fantastic co-chair @GMalekLab! Thanks to the supremely engaged #ISER2023 attendees for staying till the end and asking great questions. @iserworld
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Aparna Lakkaraju retweeted
Had a great time moderating the Lightning talks of ARVO Advance 2023 @ARVOinfo on how to get started with your research career. Thanks for all the awesome questions and fantastic talks by @NeenaHaider Dr. Aparna Lakkaraju, Dr. Jacque Duncan and Dr. Andrew Feola!
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Aparna Lakkaraju retweeted
The @LakkarajuLab shows the advantages of live imaging for investigating retinal pigment epithelium (RPE) mitochondrial dynamics in their recent @FrontCellDevBio publication. Read more about it here! bit.ly/3OZQPxK

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Aparna Lakkaraju retweeted
Glimpses of Expert Talk- From #Mechanisms to #Therapeutics for #RetinalDegeneration Speaker was Prof Aparna Lakkaraju, @LakkarajuLab, Professor, Edward and Estelle Alexander Endowed Chair for #VisionResearch, @UCSF @Pharmadept @mansukhmandviya @OfficeOf_MM @bhagwantkhuba
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