My 1st first-author manuscript is out in @eLife! This project started back in 2019 with the question “what makes a viral protein evolve a new function?” A thread:
doi.org/10.7554/eLife.83893
The Lowen Lab is recruiting post-docs! Join us at Emory University, Atlanta, to do exciting fundamental virology on influenza A viruses. Major research areas include viral evolution, transmission and virus-virus interactions.
It’s been 987 days since the last #bingo with @LangloisLab.
And while I usually don’t do bingo when I’m off campus, I made an exception for when the OG @Baric_Lab is in town.
Excited to share that our paper on injury-induced lung tuft cells is out now in @eLife! This is the fruit of an awesome collaboration with @lab_xin. Congratulations to the all authors, especially co-first authors @barrjamie and Marilena Gentile! elifesciences.org/articles/7… (1/2)
We discuss how viruses (and other microbes) from several exciting models (wild mice, dirty mice, rewilded mice, wildlings etc) impact homeostasis, disease, and subsequent infections. 2/3
We also provide some suggestions for standardization/ways to cross compare these powerful new models. All of these models have huge strengths and I am excited to see where they go next! 3/3
Our new paper in Science Advances led by Adam Kenney showing that direct infection of cardiomyocytes by influenza virus drives cardiac complications of the flu. Special thanks to @LangloisLab for engineering a cardiomyocyte-attenuated virus. ♥️🫁🦠🐁science.org/doi/10.1126/scia…
I'm looking for RAs & scientists to help launch my lab @czbiohub! We discover and deploy zebrafish viruses to capture infection dialogs with visual and molecular precision. Join us in illuminating virus infection biology in toto. czbiohub.org/careers/ or contact me directly
Delighted to share a new story led by @ShanleyRoach out now in @JVirologyjournals.asm.org/doi/10.1128…
We sought to evaluate the role of tuft cells during acute influenza infection. There were lots of fun surprises along the way... 1/5
Interestingly, while the baseline microbiome was different between wt and tuft cell KO mice flu infection drove similar changes increasing Proteobacteria. These data show how influenza impacts the microbiome independent of tuft cells or starting community composition 4/5
This work was supported by @JessicaFiegePhD and @AFranOfScience and a wonderful collaboration with @Hunter_lab and @TaliaWiggen@ShanleyRoach fell in love with tuft cells during this project and will likely have some great pics to show!
5/5
The Keystone Meetings Respiratory Viruses:New Frontiers and Viral Immunity: Basic Mechanisms and Therapeutic Applications are rescheduled to June 29th. Mark your calendars and keep an eye for new opportunities to submit an abstract!