Researcher in muscle cell biology. Addicted to signaling pathways (Wnt, Tgfb, Bmp). PI at Institut NeuroMyoGène.

Joined April 2018
66 Photos and videos
I am delighted to share our newest paper. @GarciaPaulineJ found that Setdb1 is absolutely required for muscle tissue regeneration. This by keeping ancient viral elements silenced in muscle stem cells. @EJPRareDiseases @iNeuroMyoGene @AfmPresse
Online now: Setdb1 protects genome integrity in murine muscle stem cells to allow for regenerative myogenesis and inflammation dlvr.it/T7wXZb
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Fabien Le Grand retweeted
19 Oct 2023
J'ai un dépôt ANR de Schrodinger🐈. J'ai un email qui accuse réception de ma soumission, et un autre email qui me dit que ma soumission ne sera pas évalué car pas reçu. À moins que cela soit une soumission normande🤨?
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Delighted to share our latest work on BioRxiv. During her PhD, @GarciaPaulineJ relentlessly studied the impact of removing the H3K9 methyltransferase Setdb1 in muscle stem cells. Strikingly she found Setdb1 is absolutely required for regeneration 1/n biorxiv.org/content/10.1101/…
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Read our preprint, and send us your feedback 😃. We deeply thank to the funding by @EJPRareDiseases @Telethon_France and our collaborator @t_cheung .
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This work will be presented live, next thursday at the GRC Myogenesis meeting. If you are attending, you should read the preprint so you may (1) Ask well thought-after questions or (2) Skip my talk and go swimming/running instead 😉
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Fabien Le Grand retweeted
Un poste de gestionnaire financier est à pourvoir au sein de l'INMG. Découvrez l'annonce ci-dessous 👇
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Fabien Le Grand retweeted
You asked for it #myotwitter and @Erik_Jacques_ delivered! A new 3D assay to study regulators of muscle stem cell quiescence and niche repopulation principles 'in a dish'. Our easiest method YET! What questions will you ask?
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Check out Nicolas Rose study, out in Biomaterials. He navigated between three labs/co-supervisors during his PhD, and yet successfully created very tiny 3D myotubes between pillars. This is a new tool to measure the force generated by a single human muscle cell in health/disease.
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Very enthusiastic to participate to the 8th Cultured Meat conference starting Sunday in Maastricht. Looking forward to learn about the latest developments on how to grow edible muscle "in a dish".
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Fabien Le Grand retweeted
⚠️Only a few weeks left to register to the @humancellatlas Development and Pediatric Cell Atlas Meeting in Paris🇫🇷 . November 20 - 22, 2022 .
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Fabien Le Grand retweeted
19 Aug 2022
Check out our new resource paper @iScience_CP showing dramatic changes in epigenetic and transcriptomic landscapes during muscle stem cell #quiescence exit and #aging. Congrats to @AnqiDong18 and colleagues! #myotwitter cell.com/iscience/fulltext/S…
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FASEB conference on muscle satellite cells @MuSCandReg just started 😎 with @vahabsoleimani @GilbertLab @GarciaPaulineJ
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LaLaurie mansion in New Orleans. The Dame was apparently a serial killer from the early 19th century. But her (rebuilt) mansion is a Hallmark of the french quarter.
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This morning, I arrived 3 hours and 30 minutes at the Toronto airport before my flight for New Orleans, and missed it due to spending 3 whole hours in line for the US customs. To colleagues going to @MuSCandReg meeting tomorrow: please be more prepared than me.
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Arrived in New Orleans, after so many delays. It only took 19hours from Toronto. Aaaaand... they lost my luggage! I have been expecting this 😭
Also is someone connecting in Denver airport today? #nightmarishtravel
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On a completely unrelated topic, I learned today that while one can buy rhum at the airport duty free shop, it is absolutely forbidden to open it before one reaches his/her final destination. I was asking for a friend.
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