The wonders of population genetics allow us to reveal the echoes of the tumultuous times our ancestors survived, forever imprinted in our genome. In this thread, I'll share my experience replicating one of my all-time favourite papers by @lh3lh3 and @richard_durbin
How much does your medical history reveal about your future?
As a team effort of @MoritzGerstung and @ewanbirney's labs, we present Delphi-2M, a transformer for modelling future health based on past medical history.
nature.com/articles/s41586-0…
Recently visited SF's @exploratorium (an awesome place, highly recommend). The oscillators section mentioned the synchronisation phenomenon in fireflies but used metronomes as a demo. Metronomes are fine, but they don’t glow!
Here’s a simulation of 150 fireflies shoved into a box
Introducing *fullRankMatrix*, available on CRAN! @const_ae and I developed this R package to construct full rank design matrices. Esp. relevant for binary matrices that contain linearly dependent columns. Use fullRankMatrix for accurate linear model interpretation! 📊 #rstats
Research internships have been essential in helping me find my career path. However, most internships in Europe are unpaid, making them inaccessible for many students. If you can, please consider helping a friend of mine to fundraise his internship at @DKFZ
Hi everyone! I am trying to raise some money for the dream internship I got at one of the best cancer research centers in Europe. I don't need much. Please find 2 minutes and read this post! It will help me a lot. Thank you!
telegra.ph/Fundraiser-for-th…
At this point, I am deeply thankful to @emblebi and @embl for offering paid internships. These opportunities are invaluable for many interns to access the amazing science done at these institutes
Thesis defended and my colleagues awarded me with the fancy hat 🎓
Thank you everyone who've been with me on this journey - you are fantastic scientists and friends! And thank you @MoritzGerstung and @Yates_lab for guiding me through this chapter of my life. It was fun!
The field of spatial genomics has faced challenges with diverse data types and a lack of standardised infrastructure for quite some time. Congratulations to the authors for the release of a much-needed solution!
ALT The text “SpatialData Framework” along with the SpatialData logo, showing three stacked layers in perspective, at the top a yellow tabular structure, in the middle a dark blue layer with green dots (i.e. cells), and at the bottom a lighter blue layer with a black grid representing a raster image.
The wonders of population genetics allow us to reveal the echoes of the tumultuous times our ancestors survived, forever imprinted in our genome. In this thread, I'll share my experience replicating one of my all-time favourite papers by @lh3lh3 and @richard_durbin
During my PhD interview with @Nick_Goldman, I shared this as my favourite paper, acknowledging my limited understanding of how the method works. Nick then asked me how long it'd take to replicate if the math is provided, and I somewhat naively replied, "I guess three weeks?🤔"
It took me numerous evenings of dedicated effort to replicate the task at hand. As someone with limited computational experience four years ago, I cannot stress enough how much of an underestimation the "three weeks" suggestion was 🤦♂️