BHF Fellow/Assistant Professor @WarwickLifeSci studying neurobiology of stress and feeding 🧠 - immigrant - mum of one - dog lover! She/her. Views are my own.

Joined February 2019
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PhD project alert! Come study stress circuits with me @uniofwarwick (funded by @MIBTP_BBSRC) . We'll be doing chemo- and optogenetics, in vivo calcium imaging, patch-clamp electrophysiology and a lot of mouse behaviour! Details here: warwick.ac.uk/fac/cross_fac/… Please share!

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Marie K Holt retweeted
We’re building a new center @SinaiBrain to understand the neural computations that drive behavior. Join us at this exciting hub for discovery in the heart of NYC! 🧠
πŸ“’ Calling all Systems & #ComputationalNeuroscience researchers! The #FriedmanBrainInstitute is hiring tenure-track faculty in the Department of Neuroscience @IcahnMountSinai. Learn more & applyπŸ‘‰neuroscience.mssm.edu/pdf/fa… *Please retweet & share!
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Marie K Holt retweeted
29 Oct 2024
Abusive bosses don't drive performance. They undermine it. 471 studies, 149k people, 36 countries: in aggressive workplaces, we do poorer work, collaborate less, and shirk more. Incivility breaks confidence and breeds resentment. The best way to get results is to show respect.
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Marie K Holt retweeted
We are seeking an experienced metabolomics scientist to lead our metabolomics platform at @Metabolcenter in Copenhagen.
πŸš€ π–πž 𝐚𝐫𝐞 𝐑𝐒𝐫𝐒𝐧𝐠 𝐚𝐧 𝐞𝐱𝐩𝐞𝐫𝐒𝐞𝐧𝐜𝐞𝐝 π¦πžπ­πšπ›π¨π₯𝐨𝐦𝐒𝐜𝐬 𝐞𝐱𝐩𝐞𝐫𝐭 𝐚𝐧𝐝 𝐩𝐞𝐨𝐩π₯𝐞 𝐦𝐚𝐧𝐚𝐠𝐞𝐫 𝐭𝐨 π₯𝐞𝐚𝐝 𝐭𝐑𝐞 π¦πžπ­πšπ›π¨π₯𝐨𝐦𝐒𝐜𝐬 𝐩π₯𝐚𝐭𝐟𝐨𝐫𝐦 πŸ‘©β€πŸ”¬ As one of five enabling biology and technology platforms, the πŒπžπ­πšπ›π¨π₯𝐨𝐦𝐒𝐜𝐬 𝐏π₯𝐚𝐭𝐟𝐨𝐫𝐦 is an integral part of CBMR, aiming to develop analytical strategies for metabolomics-driven systems biology in personalized health strategies. The Platform offers experimental and computational services and assistance with project planning of metabolomics-based projects on a case-by-case basis. In-house expertise and services help our scientists streamline their research, so they can achieve their research goals faster. πŸ™ To successfully lead a well-established Platform team, we aim to onboard a candidate with experience in leading and developing diverse teams and profound experience in metabolomics or relevant/equivalent techniques. 🏫 The ideal candidate has a very strong drive, naturally spearheading change in large organizations, and has a strong understanding of the inner workings of academia and health science, ideally through experience from a similar set-up in a large and excellent research institution. Read more about the position and apply below πŸ‘‡ candidate.hr-manager.net/App…
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Marie K Holt retweeted
Want to do a PhD to study how appetite and body weight are regulated by the brain? Join our team ! @IMS_MRL @Cambridge_Uni Applications are now open Check it out and get in touch if you have questions ! postgraduate.study.cam.ac.uk…

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Marie K Holt retweeted
JOB ALERT! Join our growing team @BristolUni to study autonomic regulation of coronary blood flow in health and disease. You will be part of a vibrant collaborative community between @UoBPPN and @Brms_Research
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Marie K Holt retweeted
Postdoc Opportunity - focused on sensory nutrition/obesity to discover how olfactory processes drive metabolic balance using patch-clamp ephys, opto/chemo genetics, CRISPR, fos TRAP, mouse models; purposeful mentoring & career building @FSUNeuroscience neurojobs.sfn.org/job/38007/…

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26 Sep 2024
Read about the latest circuit tools for studying neuromodulator & neuropeptide signaling in vivo! We describe the use of neurochemical sensors, actuators, and probes in our lab’s first Review @ScienceMagazine tinyurl.com/4mcfb24w Congrats @jessie_muir & @LatinaNeuroNerd!

Check out the Kim lab's latest review out in @ScienceMagazine featuring @LatinaNeuroNerd, @tinakim_neuro and myself! science.org/doi/10.1126/scie…
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Marie K Holt retweeted
Fantastic panel with @GwynneMP talking about the power of prevention to improve health and the economy. One of the standout stats is that 40% (on track to reach 60%) of NHS currrent spend is on tackling preventable illness too late. #Lab24
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Marie K Holt retweeted
My PhD paper is out! We imaged gut neuron activity in living, eating flies (first time in history!), and found a Gut-Brain-Gut neural circuit loop that allows fruit flies to adjust their ingestion bouts based on the sucrose concentration of the food! (1/n biorxiv.org/content/10.1101/…
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Marie K Holt retweeted
5 Sep 2024
πŸ”¬Career opportunity - PhD studentship, Nottingham Trent University, UK Identification and spatial brain mapping of novel candidate metabolic rate genes Supervisors: Nik Morton @morton_nik and Rebecca Dumbell @rebeccyannie APPLY by 13.9.24: ntu.ac.uk/study-and-courses/…
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Marie K Holt retweeted
Astrocyte friends: I’m in need of advice. I’m looking for a good astrocyte antibody and a tamoxifen-Inducible Cre driver line for hippocampal astrocytes. What would you recommend?
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Marie K Holt retweeted
Be mindful about axon collateralization! We have changed some experimental strategies based on this discovery. Proud to have the cover image for this journal issue and also a β€œFeatured Article” designation! Happy times. jneurosci.org/content/44/31/…
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Marie K Holt retweeted
Depletion of colonic endocrine cells reveals a gut–brain axis, that regulates host metabolism and body weight in mice @NatMetabolism nature.com/articles/s42255-0… #microbiota #weightloss

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Marie K Holt retweeted
***Funded PhD Opportunity*** PhD studentship available as part of my upcoming #UKRI_FLF project looking at changes in appetite, energy intake, and energy expenditure during weight loss. Deadline is 31st May, 2024. Please RT and share! findaphd.com/phds/project/th…
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Targeting gut endocrine cells is a logical yet challenging therapeutic target with small molecule GLP1RAs looming. Here the team @CamMetaboNet uses chemogentics to link K cells to reduction of food intake @MolMetab sciencedirect.com/science/ar… #weightloss
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23 Apr 2024
What does everyone do when the grant they were awarded is no longer enough to cover the price of equipment because of inflation? Clearly I've missed a trick, but the application asked for quotes, so I've only costed the price at time of submission. Small grant, no wiggle room.

ALT Frustrated Upset GIF

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Marie K Holt retweeted
Stress can trigger willful seeking of a starvation-like state in certain female mice predisposed to higher anxiety. Now published and downloadable here: authors.elsevier.com/a/1iyP-… Congrats to lead-author @haganK, @Oren_Amsalem, @andrewlutas, and the whole team. Feedback welcome!

What triggers anorexia nervosa? We find that chronic stress can trigger willful seeking of a starvation-like state in mice. As in humans, this was enriched in female mice, particularly those predisposed to stress. biorxiv.org/content/10.1101/… 1/7
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