PhD student in developmental psychology, focussing on environmental and genetic influences on the wellbeing and life course of autistic people
Joined June 2021
- Tweets 55
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(1/9) 📣 OUT NOW! 📣
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in @JAACAPOpen
doi.org/10.1016/j.jaacop.202…
A (long) thread of our main findings ⤵️
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(8/9) To conclude, due to inconsistent associations and limited generalizability, the autism polygenic score does not have clinical utility and should only be applied for scientific purposes. Improvements are needed for a deeper understanding of autism’s polygenic underpinnings
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(9/9) It was a great pleasure working on this with Morgan Morgan, Ilan Libedinsky, Chloe Austerberry, Sander Begeer, @dr_appie, @Gelironald and Tinca Polderman
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Melanie retweeted
16 May 2025
📢Out Now 📢
In a GWAS meta-analysis, @Gelironald and colleagues identified 11 independent genome-wide significant loci associated with age at onset of walking.
in @NatureHumBehav
tinyurl.com/4m5twe46
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Melanie retweeted
29 May 2024
Fully funded PhD studentship available! Join our lab investigating genetic and environmental influences on early child behaviour. Gain transferable skills in scientific enquiry, coding, writing, presenting & more, deadline June 15th tinyurl.com/4faejtsm RTs appreciated!
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Melanie retweeted
20 Mar 2024
A review and meta-analysis of studies that assess the relationship between the autism polygenic score and autism diagnosis, and autistic, behavioral and neurobiological traits: medrxiv.org/content/10.1101/…
Led by @MMPdeWit 🧬🧠
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Melanie retweeted
19 Mar 2024
Out now! The profile article of our BIObanks Netherlands Internet Collaboration (#BIONIC) project, a #GWAS dataset of >66,000 🇳🇱 subjects to study the genetic base of #Depression. Big shoutout to @Floris_Huider for his great work on the data and the paper: bit.ly/3vgIH6u
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📢Our preprint is online! 📢
Systematic Review and Meta-Analysis: Research using the Autism Polygenic Score
medrxiv.org/content/10.1101/…
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We conclude that the current autism polygenic score is consistently associated with autism diagnostic status and autistic traits, but overlap between autism and other traits and conditions is not, from publications to date, explained significantly by the autism polygenic score.
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With many thanks to my amazing team of co-authors
@morganjmorgan @ILibedinsky @ChloAusterberry @SanderBegeer @dr_appie @Gelironald and @tincatwin
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Melanie retweeted
25 Jan 2024
We're hiring!🎓🚀3PhD 1PD, all 4y funding @VUamsterdam @NTRscience @GENE_Amsterdam
#TwinWise (@brunosauce Hofman & me)
workingat.vu.nl/vacancies/ph…
workingat.vu.nl/vacancies/po…
SCANNER (@wonu_akingbuwa @tincatwin van 't Ent & me) #autism
workingat.vu.nl/vacancies/ph…
workingat.vu.nl/vacancies/ph…
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