Physician-scientist. Neuroimmunologist. Multiple Sclerosis specialist. @WUSTLmed
Joined October 2018
- Tweets 237
- Following 184
- Followers 730
- Likes 1,205
16 Photos and videos
Apr 24
Looking forward to joining Dr. Jiwon Oh at a @PeerView live symposium during #CMSC2026 on advancing care in #MultipleSclerosis, including the role of #BTKi. Join us 5/27 at 5 PM EDT in Charlotte or virtually: bit.ly/CharlotteMS26-T
#Neurology #MedEd
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Gregory Wu retweeted
Apr 22
Excited to see our work published in @GreenJournal group! We show that cladribine profoundly reshapes the CSF cell landscape in MS, providing new insights into treatment effects within the CNS. Thanks to all, especially @MS_ResearchDoc and Roman Smirnov! doi.org/10.1212/NXI.00000000…
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New Pathways, New Possibilities in #MultipleSclerosis: Enhance your ability to interpret clinical data to identify ideal candidates for #BTKi therapy with Drs. Jiwon Oh and Gregory F. Wu (@MS_ResearchDoc), 5/27 at 5:00 PM EDT: bit.ly/CharlotteMS26-T #CMSC2026 #neurology
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Gregory Wu retweeted
Feb 5
Overjoyed to share our new work exploring the antigen specificity of CSF-expanded CD8 T cells in #multiplesclerosis #EBV in @natimmunol 🧵1/
nature.com/articles/s41590-0…
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Gregory Wu retweeted
20 Aug 2025
🚨 Paradigm shift in #MultipleSclerosis 🚨
New study in Nature Medicine shows MS is not fixed subtypes but a dynamic continuum of states across 4 dimensions: disability, brain damage, relapses & silent inflammation.
📖 Read: nature.com/articles/s41591-0…
#MS #Neurology #AI
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Gregory Wu retweeted
17 Jul 2025
CSF cell analysis is key to understanding neurological diseases but has been limited by cell fragility. Millet Wallisky et al. introduce a rapid, one-step method for efficient CSF immune profiling
Check out the paper below 👇
jni-journal.com/article/S016…
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Gregory Wu retweeted
19 May 2025
Murphy Lab Bay #2: proving that science and chaotic shenanigans can coexist. 🙌
@SunnyKimNov2016
18 May 2025
Scientists have found that C/EBP⍺ activates an IRF8 #enhancer, driving its expression in early myeloid progenitors and specifying type I conventional #DendriticCell lineage. @washu_pathology @JingNeticist
Read more in Science #Immunology: scim.ag/3EUH8jF
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Gregory Wu retweeted
13 Feb 2025
Pleased to write this editorial with Larry Steinman about a potential novel antibody in MS
neurology.org/doi/10.1212/NX…
Original manuscript here:
neurology.org/doi/10.1212/NX…
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Gregory Wu retweeted
3 Feb 2025
Happy to share this collaborative work looking at long term results of a high efficacy DMT in early #MS #ocrelizumab @OMRF @AaronBosterMD @drbarrysinger @Brandon_Beaber @MSViewsandNews neurology.org/doi/10.1212/WN…
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5 Jan 2025
So proud of this collaborative work! Thanks to all involved, including @Clodida @BrianEdelson2 @maxim_artyomov @mzhlab @jsabatino37
2 Jan 2025
1/ I am thrilled to share our latest paper: A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations, @jclinicalinvest! Thanks to @MS_ResearchDoc, @BrianEdelson2, @maxim_artyomov, and co-author Roma for this collaborative effort!
ALT bit.ly/40fVfaS
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Gregory Wu retweeted
12 Dec 2024
@mzhlab I am proud to share our manuscript published in @ANA_journals today. 🥳doi.org/10.1002/ana.27157
We used data-driven approaches to analyze paired #CSF and blood #FlowCytometry of 8,790 (discovery) 3,201 (validation) patients.
A #tweetorial 🧵1/16
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Gregory Wu retweeted
12 Dec 2024
Exciting news! Our new paper is published at Annals of Neurology!
Check it out to see how large-scale CSF and blood flow cytometry can reveal disease clusters to improve diagnosis and understanding
doi.org/10.1002/ana.27157
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Gregory Wu retweeted
10 Dec 2024
Using sc-RNA-Seq to delineate T cell changes in AD, demonstrates an up regulation of exhaustion markers in CD8 T RM cells within 5xFAD mouse brain.
Check the link below 👇
jni-journal.com/article/S016…
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Gregory Wu retweeted
10 Nov 2024
I'm excited to announce that Jennifer Lawrence's thesis work is now out! Check it out here:
JCI Insight - Microglia drive diurnal variation in susceptibility to inflammatory blood-brain barrier breakdown insight.jci.org/articles/vie…
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Gregory Wu retweeted
28 Sep 2024
Post-mortem MS brain display PD1 Granzyme B tissue-resident memory (Trm) T cells in MS lesions, in contact with EBV infected B cells promoting local CNS inflammation.
Check out👇 this 2023 interesting study from @FrancescaAloisi
sciencedirect.com/science/ar…
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Gregory Wu retweeted
22 Sep 2024
Another super important TRP paper that I just came across because of a new paper on how fever impacts CD4 T cell responses by @DarrenHeintzman.
Linking the TRPV paper here to add it to this thread:
pubmed.ncbi.nlm.nih.gov/3283…
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Gregory Wu retweeted
15 Sep 2024
Excessive and repetitive Ampicillin treatment alter the gut-brain axis. Ampicillin induce neuroinflammation through NfL, NOS2 and GFP release.
Check out 👇 the work by @TouilBoukoffa team.
jni-journal.com/article/S016…
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Gregory Wu retweeted
9 Sep 2024
Incredibly excited to share our latest work exploring the antigen specificity of clonally-expanded CSF-enriched CD8 T cells in MS #multiplesclerosis #Tcells #EBV 🧵1/
biorxiv.org/content/10.1101/…
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Gregory Wu retweeted
Attending #ASCP2024? Be sure to stop by our booth and say hello to Nikki!
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