We study the biochemistry, biophysics, and molecular structures of proteins in epigenetics and cancer @UPenn @PennMedicine

Joined July 2021
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The Marmorstein lab is looking for a postdoc to join us at the University of Pennsylvania in Philadelphia to work in the area of acetyl-CoA metabolism using cryo-EM, biophysical and biochemical approaches. Visit the post on jobRxiv for details.jobrxiv.org/job/perelman-sch….
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Thanks to James Petersson and his group for helping us uncover the molecular of NAA38 in NatC acetyltransferase function: doi.org/10.1016/j.str.2022.1…

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Thanks to Nate Snyder and his group for helping us uncover the allosteric role of the citrate synthase homology domain of ACLY: doi.org/10.1038/s41467-023-3…

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Congratulations to Vera Moiseenkova-Bell for leading the new Institute for Structural Biology at UPenn-PSOM: players.brightcove.net/pages…

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Thanks to Gerd Blobel for getting us interested in HRI and to Dan Ricketts and Ryan Emptage for putting together a great story on the importance of HRI dimerization doi.org/10.1016/j.jbc.2022.1…

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Had a great FASEB meeting on Reversible Protein Acetylation in Dorado. Thanks to all who participated!
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Thank you to Xiaolu Yang for getting our lab interested in G6PD mechanism and congratulations to Xuepeng, Katie and Elana on their collaborative efforts on understanding the allosteric role of the structural NADP molecule, pnas.org/doi/suppl/10.1073/p…
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Marmorstein Lab retweeted
Friday Research Discussions (in person) with the Marmorstein Lab "Proteins that manipulate histones and hydroxy-steroids" April 1st @ 4pm @BMBGGUPENN
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Thanks to Lin Guo and Jim Shorter for their help and congratulations to Leah Gottlieb for publishing her work on the role of N-terminal acetylation on Huntingtin protein aggregation, doi.org/10.1016/j.jbc.2021.1…

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The Marmorstein lab is looking for a postdoc to join us at the University of Pennsylvania in Philadelphia to work in the area of acetyl-CoA metabolism using cryo-EM, biophysical and biochemical approaches. Visit the post on jobRxiv for details.jobrxiv.org/job/perelman-sch….
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For more details on the lab, visit:med.upenn.edu/apps/faculty/i…
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Marmorstein Lab retweeted
18 Aug 2021
Daxx represents a new type of protein-folding enabler, excited that this work with Xiaolu Yang, @MarmorsteinLab, @JiabeiLin et al. is out in @Nature! nature.com/articles/s41586-0…

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Was great to have our first lab outing since 2019 to finally say farewell to our postdoc alum @andreaach16 last night! So excited to see what you will accomplish.
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