Mauri lab based @UCL. Our research interests include B cells, regulatory B cells and their roles in autoimmune disease and cancer. #lupus #arthritis #cancer
Joined March 2016
- Tweets 1,702
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- Followers 1,486
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76 Photos and videos
Pinned Tweet
15 Jul 2025
Thrilled to share our new preprint! 🎉 We uncover a novel subset of double negative (DN1) Bregs expanded in RCC, located within immature tertiary lymphoid structures, that suppress cytotoxic T cell activation. Led by @DrZaraBaig & Izzy, with support from all our collaborators.
13 Jul 2025
Tumor-infiltrating CD27-IgD- regulatory B cells suppress cytotoxic CD8 T cell responses in renal cell carcinoma biorxiv.org/content/10.1101/… #biorxiv_immuno
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Mauri Lab UCL retweeted
Environmental pollution may worsen asthma 🌍
This research shows that 3-methyl-4-nitrophenol (MNP) promotes ER stress in airway epithelial cells, driving oncostatin M → macrophage TNF-α → increased allergic inflammation.
🔗 doi.org/10.1093/cei/uxae078
#Immunology #Asthma
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Mauri Lab UCL retweeted
A huge thank you to everyone who took part in the 2026 BSI elections!
We're pleased to welcome our newly elected committee members and trustees, who will help guide and support the Society's work over the coming years.
Meet the successful candidates 👇
ALT Announcement of the British Society for Immunology's committee election results for 2026. Features bold text and graphics on a blue background.
ALT Professor Leonie Taams announced as the new BSI President and Chair of the Board of Trustees. The image includes a picture of Professor Taams and a statement about her appointment.
ALT The announcement highlights Professor Megan Macleod as the new Chair for the BSI Member Representative Forum. The image features her photo alongside a quote about her role.
ALT Dr. Lucy Garner is announced as an Early Career Trustee for the BSI Board. The image includes her photo and a quote about her enthusiasm for supporting early career immunologists.
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Mauri Lab UCL retweeted
28 May 2024
📸 Mediators of #Breg induction in the tumour microenvironment
Here, researchers at @QMULBartsTheLon discuss the heterogeneity of #Bregs, cellular interactions they make with other immune cells & the tumour, and how they enable tumour escape ➡bit.ly/3DAlhco
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Mauri Lab UCL retweeted
Join us in London this September to explore how environmental signals shape immune responses, with speakers including Yasmine Belkaid, Petter Brodin and more.
📅 Abstract deadline: Monday 29 June 2026
🎟️ Register early to save!
Learn more: vist.ly/54ad6
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Mauri Lab UCL retweeted
Neutrophil extracellular traps (NETs) are emerging as both biomarkers and drivers of rheumatoid arthritis, linked to disease activity, treatment response and key pathogenic pathways. Targeting NET formation could open new therapeutic avenues in RA.
doi.org/10.1093/cei/uxag011
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Mauri Lab UCL retweeted
Open‑access review shows how immunotherapy has transformed advanced melanoma treatment, with many patients now likely cured, and highlights emerging options for those who don’t respond to current therapies.
doi.org/10.1093/cei/uxaf073
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Mauri Lab UCL retweeted
This new open‑access study shows the β‑blocker nebivolol prevents T‑cell exhaustion and boosts cytotoxicity against breast cancer cells via β₂‑adrenergic receptor–dependent signalling, highlighting a potential new immunomodulatory strategy.
vist.ly/4zh43
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Mauri Lab UCL retweeted
This study highlights 2B4 (CD244) as a key receptor driving Staphylococcus aureus–associated allergic inflammation. SEB binds and activates 2B4, amplifying eosinophil responses, pointing to a promising therapeutic target.
📄 bit.ly/4my2B1e
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Mauri Lab UCL retweeted
🧬 A rare SCID case highlights the complexity of inborn errors of immunity, showing how concomitant RAG‑2 and LRBA variants can coexist and why functional immunological testing is crucial when interpreting novel genetic findings, even years post‑HSCT.
👉 vist.ly/42fic
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Mauri Lab UCL retweeted
📢 Autoimmune overlap spotlight: MOG‑IgG and NMDAR‑IgG can coexist, causing MNOS, often presenting with psychiatric symptoms or seizures.
Most patients respond to immunotherapy, but relapse risk is higher, making early recognition crucial.
🔗 doi.org/10.1093/cei/uxad109
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Mauri Lab UCL retweeted
📢 New open‑access study identifies PSMB8 as a biomarker predicting proton pump inhibitor response in pediatric eosinophilic esophagitis, supporting more personalized treatment decisions.
🔗 doi.org/10.1093/cei/uxag012
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Mauri Lab UCL retweeted
A simpler, highly specific way to detect AIH? This study shows that MF-SMA patterns on vascular smooth muscle cells are easy to recognize and match gold-standard specificity, offering a more reliable diagnostic approach. 🧬
doi.org/10.1093/cei/uxae051
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Mauri Lab UCL retweeted
Early splenectomy delays inflammation and reduces joint damage in a mouse model of autoimmune arthritis, highlighting a surprising protective role when done at early stages. 🧬
doi.org/10.1093/cei/uxae013
#Immunology #Autoimmunity #Arthritis
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Mauri Lab UCL retweeted
💡 How would you spark interest and conversation about #immunology?
The BSI Communication & Engagement Grant supports new engagement projects - any format, any audience. Up to £1,000 available! #PublicEngagement
Deadline: 1 June 2026. Apply here: bit.ly/3Y9j8gm
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Mauri Lab UCL retweeted
Struggling with #omics data in #R?
Join our hands-on training designed for wet-lab scientists with minimal bioinformatics background. We've had over 3,000 participants and received a 9.5/10 rating.
Secure your spot for Sept or Dec 2026: vist.ly/53gdp
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Mauri Lab UCL retweeted
🫁 #WorldAsthmaDay
Open‑access research reveals how reduced IL‑10 from FoxP3⁺ Treg cells in allergic eosinophilic asthma may be partially compensated by CD46‑driven FoxP3⁻ IL‑10⁺ regulatory T cells, shedding light on immune balance in asthma.
👉 doi.org/10.1093/cei/uxag017
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Mauri Lab UCL retweeted
Are you an Early Career Researcher working in immunology? #EIS26
The BSI Exeter Immunology Group is hosting a symposium this June with a strong ECR focus, offering a great opportunity to connect and share ideas.
Submit an abstract to get involved 📝 vist.ly/4z7m2
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Mauri Lab UCL retweeted
Hey #UKimmunomet26 attendees 👋
Come and say hello at the BSI stand! Chat with Laura Franklin (our Journals Manager) and Ellie Pearson (intern at the BSI) about our journals, how to submit your work, and the other opportunities we offer.
We’d love to see you there!
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Mauri Lab UCL retweeted
⏰ Early bird deadline: Thursday 2 April #UKimmunomet26
Hear from leading speakers across the UK, Europe and beyond at the UK’s top immunometabolism meeting. Plus dedicated networking and a conference dinner to connect with peers.
Register now to save: vist.ly/4wr6t
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Mauri Lab UCL retweeted
IFNγ from activated CD4⁺ T cells plays a key role in driving lupus by promoting B‑cell differentiation and autoantibody production. Mice lacking IFNγ showed reduced symptoms, highlighting these cells as a potential therapeutic target.
doi.org/10.1093/cei/uxaf079
#Immunology
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