Associate Professor of Biophysics at Johns Hopkins, theory and computational modeling in cell biology.

Joined April 2018
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Margaret Johnson retweeted
Open science tools like Simularium help bring science to life. @mejohnson81 shares how it has helped her stoke curiosity in @JohnsHopkins students and work with colleagues across timezones. #OpenScienceWeek
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Margaret Johnson retweeted
My PhD work is online! Huge thanks to my advisors Carl and TJ, and collaborators! @taekjip @maryamyamadi @FuYiben @Mejohnson81
5 Aug 2025
GAGA zinc finger transcription factor searches chromatin by 1D–3D facilitated diffusion nature.com/articles/s41594-0…
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Does protein dimerization always help targeting and dwell time on DNA? Not for a population! Spacing between DNA targets has big impact. Nonspecific binding and facilitated (1D) diffusion play a key role. Super proud of Mankun Sang’s work! doi.org/10.1101/2025.02.18.6…
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Can sensing of membrane receptors be switched on at tunable threshold densities, without active processing? Proud to share this preprint led by the awesome Dr Foley, please check it out!
26 May 2025
I’m excited to finally share our new preprint! Membrane-associated assembly processes like CME function as precisely-tunable, spatially targetable, robust on/off switches that don’t require energy at decision-time. #biophysics arxiv.org/abs/2505.17290
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Margaret Johnson retweeted
I am thrilled to have the opportunity to serve the @BiophysicalSoc in this role. The society has been so important and impactful for me and my #science over the arc of my career, and I am delighted to give back.
Replying to @BiophysicalSoc
@KarenFlemingPhD will serve as President-elect @sp_harris1 was elected to a second term as Treasurer 2025-2028 Council Members will be @doctheagrif @CavagneroLab @renaemryan1 @ryotaiino
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Margaret Johnson retweeted
Congratulations to @KarenFlemingPhD of JHU Biohysics, president-elect of the Biophysical Society! Very exciting!!
Replying to @BiophysicalSoc
@KarenFlemingPhD will serve as President-elect @sp_harris1 was elected to a second term as Treasurer 2025-2028 Council Members will be @doctheagrif @CavagneroLab @renaemryan1 @ryotaiino
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Margaret Johnson retweeted
Please nominate one of your amazing junior or mid career colleagues for the @BiophysicalSoc Theory & Computation Subgroup Award They'll receive a cash prize & speak at the 2025 annual meeting in sunny Los Angeles☀️🌴 biophysics.org/awards-fundin… Nominations due Aug 1, 2024 ⏰

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The Theory and Comp subgroup from Biophysical Society has an early and a mid-career award, apply before August 1! please RT biophysics.org/awards-fundin…

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Margaret Johnson retweeted
Very excited to share our Jeff (Anmin) PhD paper in collaboration with @Mejohnson81 and Phil Robinson demonstrating that Dynamin 1 undergo Dimensional Reduction: (1) recruitment to the membrane and (2) clustering, to make endocytosis happen. nature.com/articles/s41467-0…
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Excited to share our latest paper: no matter how stable the macromolecular assembly, kinetic traps can always be avoided by exploiting nonequilibrium protocols. awesome effort by Adip Jhaveri and former undergrads Spencer and Yian! pnas.org/doi/10.1073/pnas.24…

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Having diverse subunits in the complex helps expand the solution space. Automatic differentiation is a super cool method for optimization in large parameter spaces, thanks Spencer!
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Alternate paper title: "Unsupervised machine learning discovers optimal pathways of self-assembly" @murugan_chicago
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Margaret Johnson retweeted
Want to work on biological physics at Johns Hopkins? (OK, or other areas of physics which I accept are also interesting). We have a prize postdoctoral fellowship, with competitive pay, some independent research budget - Dec. 1 deadline academicjobsonline.org/ajo/j…
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Margaret Johnson retweeted
17 Sep 2023
The 2024 Biophysical Society meeting will be in Philadelphia. The abstract deadline is just about two weeks away. We have the BPS Lecture by @CarolynBertozzi and an exciting program by @TheVillaLab and Ibrahim Cisse. And the dance is back!
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Excited to share our preprint where we 'discover' kinetic protocols for macromolecular self-assembly of highly stable complexes biorxiv.org/content/10.1101/… Awesome grad student Adip Jhaveri and former undergrad Spencer Loggia, automatic differentiation is a cool method!
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Johns Hopkins Biophysics is hiring tenure-track faculty as part of a faculty expansion at JHU! All ranks, all areas molecular to cellular, theory, comp. and experiment.
One of my departments is hiring - Hopkins is a great place to work, and I'm happy to answer questions: biophysics.jhu.edu/2023/08/2…
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Margaret Johnson retweeted
Can we teach bacteria to autonomously synthesize and assemble biomaterials? @Qi_Xieqi and coworkers thing so! Excited to share our work on secretion-catalyzed assembly, out now in @angew_chem. Bacillus's translocon can act like a nano silk spinneret! onlinelibrary.wiley.com/doi/…
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Margaret Johnson retweeted
We are hiring in the Dept. of Biophysics & Biophysical Chemistry @BiophysicsJHMed at @HopkinsMedicine ! We invite applicants working in any related field including cryo-ET, cryo-EM, computational biology, single molecule Biophys. and more. Please RT! apply.interfolio.com/128991
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