Super exited to share the second chapter of my dissertation with the world! TLDR; when we revisit Lewontin’s Paradox of Variation in plants with k-mers cool things happen (1/19) 🧵👀
Nucleotide diversity 🧬 and k-mer-based metrics of genetic diversity across 112 plant 🌱 species, amounting to over 205 terabases of DNA sequencing data from 27,488 individuals academic.oup.com/evlett/adva…#biodiversity#genomics
Our paper on using inferred tree sequences for accurate pop gen inference (by training neural nets on tree seqs *inferred* from simulated data) is now published in MBE: academic.oup.com/mbe/advance…
Orig rambling thread on preprint below:
Thread about a new preprint from the lab, led by Logan Whitehouse and Dylan Ray, about tree-sequences. The teaser tagline: why use tree sequences for evolutionary inference when you can directly examine population genetic alignments? biorxiv.org/content/10.1101/…
I'm recruiting students / postdocs to join my new lab at the University of Rochester for Fall 2025 onwards! If you're interested in phylogenetic comparative methods, genome evolution, and/or computational biology, please get in touch! More info:
mhibbins.github.io/
Breaking my social media hiatus to promote mine and @moriahyoung's new paper!! We look at how warming & herbivory interact to affect multiple plant traits, and we point to the need for more long-term studies that include abiotic and biotic stressors 🌱 esajournals.onlinelibrary.wi…
My lab has 2 postdoc positions funded by #NIH and #NSF to study novel ORFs and translational regulation in Arabidopsis and crops. Please retweet. jobs.plantae.org/jobs/205060…
Check out our new preprint! We show genetic loci assoc. w/adaptation to rust pops, and rethink reciprocal transplants for studying parasite local adaptation.
Local adaptation of both plant and pathogen: an arms-race compromise in switchgass rust biorxiv.org/content/10.1101/…
People. There is software to calculate π correctly (including invariant sites). github.com/ksamuk/pixygithub.com/RILAB/mop
If you insist on using vcftools, please consider this equally accurate but substantial speedup I found online:
Super exited to share the second chapter of my dissertation with the world! TLDR; when we revisit Lewontin’s Paradox of Variation in plants with k-mers cool things happen (1/19) 🧵👀
I feel like this thread is getting long, so I'm gonna stop here, but there are lots of details in the preprint. I welcome any feedback people have on this work. I am super excited to have this project released out into the world!😁(18/19)
If this work interests you, I am looking for post-doctoral opportunities. I'm looking to graduate Spring 2025 and I'm happy to collaborate on writing a postdoctoral fellowship application. You can read the first chapter of my dissertation here: (19/19)
doi.org/10.1093/genetics/iya…