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MultiPark at LundU @MultiparkL

MultiPark is a translational programme ranging from experimental pre-clinical research to studies on the life situation of patients with #neurodegeneration.

Joined May 2020
  • Tweets 1,141
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  • Followers 858
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Important Update from MultiPark! We want to inform you that MultiPark will no longer be active at X. You can continue to follow our latest research, news, and updates on LinkedIn 👉 linkedin.com/company/multipa… Thank you for your support, and we look forward to staying in touch!

MultiPark- Multidisciplinary Neuroresearch | LinkedIn

MultiPark- Multidisciplinary Neuroresearch | 3,326 followers on LinkedIn. Multidisciplinary neuroscience research at Lund university. | MultiPark (Multidisciplinary Neuroresearch) is a strategic...

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Nano Letters@NanoLetters
13 Feb 2025
PEDOT is going one-dimensional! Lithography-free conductive polymer nanowires were interfaced with both algae and human blood stem cells paving the way for 1D organic bioelectronics. @lunduniversity @nanolund @MultiparkL @HjortsX @OlssonRoger go.acs.org/chH
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BioFINDER@biofinder_study
20 Jan 2025
A new The Swedish BioFINDER study paper in collaboration with WRAP has been published in @Brain1878 ! academic.oup.com/brain/advan… Find our key findings 👇

APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-β

Cicognola et al. investigate the relationship between the APOE4 gene—the strongest genetic risk factor for Alzheimer’s disease—and tau. They find that the

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The glymphatic system, specialized in clearing waste from the brain, is linked to various neurodegenerative diseases. However, the impact of heart failure on the glymphatic system's function remains poorly understood.
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To address this, @Iben_Lundgaard and collaborators explored how myocardial infarction in mice impacted their glymphatic function.
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"In this study we identify the glymphatic system as a new mechanism contributing to the well-established link between cardiovascular pathologies and neurodegeneration" says Marios Kritsilis, lead author of the project. Read more about their findings 👉 doi.org/10.1093/brain/awae41…

Loss of glymphatic homeostasis in heart failure

Heart failure can lead to reduced cerebral blood flow, neurodegeneration and cognitive decline. In a mouse model of heart failure, Kritsilis et al. show th

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Congratulations Gemma!
Gemma SalvadĂł@gesalbla
17 Jan 2025
Such an honour to receive the young investigator award from my favourite conference. Especially when shared with these amazing researchers! #HAI2025
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Patrik Brundin MD PhD@BrundinPatrik
8 Jan 2025
Great review on #stemcell therapies from @Kirkeby_Lab who is affiliated with @Lund_Stem and @MultiparkL at @medfak_LU @lunduniversity
ESC & iPSC News
@ESC_iPSC_News
8 Jan 2025
Since the derivation of hPSCs, technologies to control their differentiation and manufacturing have advanced immensely, enabling increasing numbers of clinical trials with #hPSC-derived products. 🔎 Learn more in this @CellStemCell review. bit.ly/41ZMTp5
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The glymphatic system, a specialized waste-clearing network in the brain, plays a role similar to the lymphatic system in the rest of the body. Changes in this crucial system have been linked to neurodegenerative diseases such as Parkinson's and Alzheimer's.
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However, a known limitation of DTI arises when nerve fibers cross—an issue affecting about 90% of the brain's white matter. In their study, the researchers demonstrated how fiber crossing impacts DTI measurements of the perivascular space and the assessment of glymphatic flow.
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This work highlights both the potential and the challenges of using DTI in glymphatic research, paving the way for improved techniques to study brain health. Read more about their findings here 👉 doi.org/10.1093/braincomms/f… Lead author: Charalampos Georgiopoulos

Diffusion tensor imaging along the perivascular space: the bias from crossing fibres

Georgiopoulos et al. report that crossing fibres significantly affect diffusion tensor imaging along the perivascular space, raising concerns about its rel

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Daniella Rylander Ottosson@Ottossonlab
23 Dec 2024
Happy and honoured to have been awarded a STIAS: Stellenbosch Institute for Advanced Study fellowship for 2025! Look forward to spend the autumn in South Africa 🇿🇦! stias.ac.za/fellows/daniella… @lunduniversity @MultiparkL @Lund_Stem @medfak_LU @Ottossonlab

Daniella Rylander Ottosson | STIAS: The Stellenbosch Institute for Advanced Study

For 25 years, the Stellenbosch Institute for Advanced Study (STIAS) has cultivated a unique environment where unexpected connections lead to groundbreaking insights.

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Biomarkers have transformed Alzheimer's disease diagnosis, and a similar breakthrough is needed for Parkinson's disease and related disorders, known as Parkinsonian syndromes (PS).
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Recent research highlights corticotropin-releasing hormone (CRH) as a promising biomarker candidate for PS. @OskarHansson9 and collaborators investigated this link, read about their results here 👉 doi.org/10.1093/braincomms/f… Lead authors: @atulkumar1301 and Bárbara Fernandes Gomes

Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders

Fernandes Gomes et al. report the downregulation of CSF corticotropin-releasing hormone (CRH) in parkinsonian disorders, and associations with cognition, c

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MultiPark at LundU retweeted
Daniella Rylander Ottosson@Ottossonlab
1 Dec 2024
Check out the latest reportage from KAW on our reprogramming project!👩‍🔬🧠 @Lund_Stem @MultiparkL @lunduniversity @WISSummit
KAW@KAWstiftelsen
25 Nov 2024
A new way to treat neurological diseases such as #Alzheimer #schizophrenia and #epilepsy could be the result of research by @Ottossonlab @lunduniversity on a cell called Parvalbumin #KAW100 #neurology Watch the video! youtu.be/54K7Kt46Yzo
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Daniella Rylander Ottosson@Ottossonlab
1 Dec 2024
Happy to share our latest preprint on glia reprogramming to human parvalbumin interneurons! @Lund_Stem @MultiparkL @CellRepJrnl @biorxiv_neursci @Ottossonlab @ParmarLab @NanoLund @lunduniversity
bioRxiv Neuroscience@biorxiv_neursci
11 Sep 2024
Generating human parvalbumin interneurons through 3D glia reprogramming biorxiv.org/cgi/content/shor… #biorxiv_neursci
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LluĂ­s CamprubĂ­ Ferrer@lluis_camprubi
29 Nov 2024
The episode I've been most excited about is here. I had the honor to chat with Prof. Bart de Strooper, one of the most brilliant minds researching Alzheimer's today. What an absolute masterclass it was. Listen to it, you won't regret it. @MultiparkL open.spotify.com/episode/0xb…

Episode 15 - Rewriting Alzheimer's

Meet Our Scientists · Episode

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Genetic risk factors can vary between populations. The T369M variant in the GBA1 gene has been linked to an 80% increased risk of Parkinson's disease. However, recent findings suggest this association might not apply to the Swedish population.
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Lead author: @BrolinKajsa Link to article 👉 doi.org/10.1016/j.parkreldis… Are you intrigued by genes and Parkinson's disease? Then tune in to Maria's MultiPark podcast episode to hear about her journey as a scientist and her research 🎧 open.spotify.com/episode/5E2…

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#Parkinson #genetics #GBA1 #neurodegeneration #neuroscience #LundUniversity
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