Network Modelling Research Group @ Koç University #systemsbiology #networks #multiomics #dataintegration
Joined July 2022
- Tweets 26
- Following 33
- Followers 80
- Likes 11
9 Photos and videos
NetLab retweeted
1 Aug 2024
On #WorldLungCancerDay, we are very excited to share our latest paper @AdvSciNews on a novel bioengineered lung tumor model which mimics the aberrant sulfation of tumor matrices! 🫁 🧫🔬🧬
Full text: onlinelibrary.wiley.com/doi/…
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Our new tool, pyPARAGON, for network-based omic data integration is now online! @KaanariciM 👏👏
15 Jul 2023
Unveiling Hidden Connections in Omics Data via pyPARAGON: an Integrative Hybrid Approach for Disease Network Construction biorxiv.org/cgi/content/shor… #bioRxiv
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Sina Dadmand and Şeyma Benge Uysal's work on the functional stratification of cancer drugs through integrated network similarity and exploring drug resistance patterns among cell lines, was presented by Sina Dadmand @RECOMBconf conference.
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NetLab retweeted
19 Apr 2023
Our new preprint is now online! Bengi (@bengiruken)-Kaan (@KaanariciM)-Cansu (@hcansud) worked together to show that networks of neurodevelopmental disorders and cancer can have shared mutations, proteins, and pathways differing in mechanisms, signaling strength, and outcomes.
17 Apr 2023
Neurodevelopmental disorders and cancer networks share pathways; but differ in mechanisms, signaling strength, and outcome biorxiv.org/cgi/content/shor… #biorxiv_sysbio
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Cancer latent drivers can additively intensify the signal when coupled with other activating mutations. They have low frequency and escape idenfication. In this study, we explored the potential impact of “latent drivers” on cancer progression and cataloged 155 latent drivers.
22 Feb 2023
@bengiruken, @ntuncbag et al use a statistical methodology to identify potential latent driver mutations from public cancer bulk sequencing data.
@NetLab14
nature.com/articles/s42003-0…
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NetLab retweeted
21 Oct 2022
🎉Rounding out this first week of our Emerging Investigators highlights is Nurcan Tuncbag @ntuncbag with this excellent review on multi-omics computational approaches and their clinical applications!
Read it in full below 🔽
pubs.rsc.org/en/content/arti…
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We are happy to be part of this collaborative work. Congrats Sina @sina_dadmand for his first paper!
25 Oct 2022
Our COVID-19 study is out. A great collaboration we had with @NozluLab, @ntuncbag, @NetLab, @oergonul1, Fusun Can @kuiscid to determine COVID-19 associated network in plasma. @KUTTAM, @KocSciences
onlinelibrary.wiley.com/doi/…
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NetLab retweeted
25 Oct 2022
Our COVID-19 study is out. A great collaboration we had with @NozluLab, @ntuncbag, @NetLab, @oergonul1, Fusun Can @kuiscid to determine COVID-19 associated network in plasma. @KUTTAM, @KocSciences
onlinelibrary.wiley.com/doi/…
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We have participated to @HBioinformatics with whole Network Modelling Lab!
For details on our presented posters:
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@KaanariciM has presented his method called PageRank-flux on graphlet-guided-network method(PRO-GGNet) for pathway reconstruction & multi-omic data integration.
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