An online resource for the neuroscience research community. Part of the @STEMCELLTech Science News service.
Joined June 2010
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May 16
GIVEAWAY! 🤩🎉
Upgrade your lab style with a pair of @STEMCELLTech science socks.🧦
To enter, subscribe to any of the Science News newsletters and get the latest updates in your field delivered straight to your inbox.
📣 You have until June 30: bit.ly/4sFyUzh
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Jun 12
Investigators identify KAT7 as an epigenetic driver of microglial mitochondrial immunity, linking chromatin remodeling to neuroinflammation and #Alzheimers disease progression. 🧠
Discover more at @NeuroCellPress:
📘 bit.ly/4giCj3D
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Jun 12
Here's a review to bookmark!
Researchers at @ucl examined the glial nature of neural stem cells, emphasizing their heterogeneity and the stem- and progenitor-like properties shared with the differentiated glia.
🔖 bit.ly/4eDcKZS
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Jun 10
.@Yale researchers and their collaborators at Massachusetts General Hospital, the @WeizmannScience, and the @univmiami have mapped how these tumors shift from initial diagnosis to recurrence.
📰 bit.ly/4uwTXnH
📝 go.nature.com/4vHecAd
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Jun 9
Researchers led by Dr. Hyder Jinnah at @EmoryMedicine have shown that as stem cells develop into neurons, they rely less on making new #purines and more on recycling them through hypoxanthine-guanine phosphoribosyltransferase. 🧠
Read the @SpringerNature study: bit.ly/4uTdLCS
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Jun 9
Led by Dr. Jeremy Rich, a research team at @UPMCHillmanCC has shown that matrix stiffness drives #glioblastoma stem cell maintenance and radioresistance through an IQGAP3–SOX2 axis, revealing a potential strategy to enhance radiotherapy response.
🔖 go.nature.com/4e8iUzQ
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Jun 5
Researchers from @MedSchool_KU have found that post-thaw #OxidativeStress is the main cause of neural organoid failure after #cryopreservation. 🥶
Antioxidant treatment during recovery significantly improves cell survival, proliferation, and organoid viability.
🔓 bit.ly/4odnfX1
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Jun 4
A new study shows that #electroacupuncture promotes recovery after #stroke by shifting astrocytes from a harmful inflammatory state to a reparative state through SIRT1–NF-κB signaling, enhancing synaptic repair and neurological function. 🧠
Read the study: bit.ly/4arBemk
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Jun 1
A @braincancercan-funded study led by Dr Ian Lorimer at @OttawaHospital is investigating whether blocking immune-suppressive #macrophages can improve immunotherapy effectiveness against #glioblastoma. 🧠
Learn more: bit.ly/4o3KWRN
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May 28
🧠 Researchers with Mathilde Bizou combined spatial transcriptomics with region-resolved endothelial single-cell RNA sequencing in the postnatal mouse brain to map cortical and thalamic neurovascular unit communication dynamics.
@NatureComms | go.nature.com/4v5p0rq
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May 27
🧠 Scientists tested whether ferroptosis-related vulnerability contributes to the regulation of hippocampal neural precursor cells and their progeny.
@CellStemCell | bit.ly/4e6OJKw
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May 26
Amir Hossein Mansourabadi and scientists at @uOttawa uncovered a bidirectional crosstalk between Oncostatin M receptor and tmCLIC1 in glioblastoma, essential for fueling its malignant growth.
@sigtrans_sttt | go.nature.com/4dLWCUp
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May 25
🧠 Using a human telencephalic #organoid model, researchers perform comprehensive proteomic profiling of neural stem/progenitor cells' cilia and find enrichment in GTPase signaling.
@naturecomms | go.nature.com/4wUewgw
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May 22
📢 New in @BrJCancer reports!
A study from researchers led by Dr. Nicola Tirelli at @IITalk have shown that proneural #glioblastomas exhibit greater stemness and an increased ability to develop temozolomide resistance, while mesenchymal tumors are associated with higher CD44 expression.
🔗 go.nature.com/49gUUch
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May 21
Congratulations to Dr. Siddhartha Mitra at @CUCancerCenter on being awarded a three-year grant from the Matthew “Iron Matt” Larson Foundation for Pediatric Brain Tumors to develop CAR M therapies to treat diffuse midline #gliomas, a particularly deadly type of pediatric brain cancer. 🧠
Learn more about his work: bit.ly/4ursq8c
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May 17
.@STEMCELLTech's protocol on neural organoids is live! 🧠
Follow this step-by-step guide on processing mature neural #organoids for cryosectioning and immunofluorescence to minimize tissue damage and preserve important epitopes.
bit.ly/4tqkFhp
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May 15
Dr. Yolanda Prezado and colleagues demonstrate that Minibeam Radiation Therapy does not trigger canonical immunogenic cell death or cGAS–STING activation in #glioblastoma and #astrocyte monocultures, unlike conventional radiation therapy.
Learn more here:
🔖 go.nature.com/4wkXyaG
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May 14
The following review highlights cathepsins as emerging biomarkers and therapeutic targets in glioblastoma, summarizing current research and future directions for clinical application.
📖 bit.ly/48RPrZi
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May 13
In this @NatureComms study, scientists develop a synthetic foldamer that stabilizes transient helical regions in Aβ, reducing aggregation and improving pathology in #Alzheimers disease models.
📝 go.nature.com/4tw4SOa
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May 11
🔬 Researchers led by Dr. Luca Lo Piccolo identify a pyrazolopyridine alkaloid that reduces neuronal ER stress and improves age-related decline, highlighting a potential strategy for #neurodegenerative disease intervention.
🔖 go.nature.com/3Pbfiom
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