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Among patients with MS-related fatigue, amantadine, fampridine, and methylphenidate improved fatigue-related functioning, but no medication outperformed placebo for #fatigue severity.
#MultipleSclerosisneurologyadvisor.com/news/me…
Higher #metabolomic age relative to chronological age was associated with increased risks for vascular, unspecified, and all-cause #dementia and earlier dementia onset among adults from the UK Biobank.
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Plasma biomarkers correlate with #amyloid and tau positron emission tomography imaging measures in adults with pre-dementia stages of #AlzheimerDisease, supporting their potential utility in diagnosing and monitoring early pathology.
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Among adults with chronic migraine and medication-overuse #headache, adding #eptinezumab to brief education improved headache burden, disability, and quality of life, supporting its use in preventive management.
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A 4-metabolite #stroke score independently predicted incident ischemic stroke and improved risk prediction beyond traditional risk factors, suggesting potential utility for earlier identification of #women at elevated stroke risk.
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A multimodal deep learning framework trained on paired CT and MRI data demonstrated improved diagnostic accuracy when classifying patients with #Alzheimer disease, MCI, or normal #cognition.
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Greater basal ganglia perivascular space burden independently predicted faster longitudinal decline in #ExecutiveFunction and visuospatial skills among older adults during 11 years of follow-up.
#Cognitionneurologyadvisor.com/news/ba…
Patients with #MildCognitiveImpairment and Alzheimer #dementia demonstrated progressively worse polysomnographic sleep abnormalities than control participants, suggesting objective #sleep disruption may track with Alzheimer disease progression.
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#Stroke care disparities persist among patients experiencing #homelessness, underscoring the need for targeted protocols to improve equitable acute stroke treatment and discharge planning.
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Letters of recommendation for #neurology residency applicants were not associated with systematic racial or gender #bias in language patterns, suggesting these narratives may continue to provide equitable applicant evaluation.
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Matrix metalloproteinase-9 showed moderate diagnostic accuracy for hemorrhagic transformation after acute ischemic #stroke, supporting its potential role in risk stratification.
#IschemicStrokeneurologyadvisor.com/news/mm…
Baseline #metabolic differences in early #MultipleSclerosis showed associations with later clinical and MRI outcomes, but they did not substantially improve prognostic accuracy over standard clinical factors.
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A higher sleep-derived Brain Health Score in midlife was associated with better digital clock drawing, memory, language, and executive function performance an average of 12.6 years later
#sleep#CognitiveFunctionneurologyadvisor.com/news/sl…