A new paper sheds light on how the transcription factor BACH1 regulates the oxidative stress response, offering mechanistic insights into a key cellular pathway and potential target in oxidative stress-related diseases such as cancer, autoimmune disorders. novartis.social/6019oZzSU
Novartis has entered into a global license and collaboration agreement with @PTCBio for a Huntington’s disease program, currently in Phase II development, with the potential to become the first oral disease-modifying therapy for the disorder. go.novartis.social/3Zx6nQf
Novartis has acquired Kate Therapeutics, a preclinical stage biotechnology company focused on developing adeno-associated virus (AAV)-based gene therapies to treat genetically defined neuromuscular diseases. go.novartis.social/4ftnFDz
Novartis and @RatioTx have entered a license and collaboration agreement to advance a next-generation radioligand therapy to bring additional therapeutic options forward for patients with hard-to-treat cancer. go.novartis.social/3VkWhQj
Novartis and Schrödinger have announced a multi-target research collaboration, and an expanded software agreement that will broaden Novartis access to Schrödinger’s computational predictive modeling technology and enterprise informatics platform. go.novartis.social/3ADLcT7
Novartis, @MonteRosaTx announce an exclusive global development and commercialization license agreement to advance molecular glue degraders, including an investigational program currently in Phase 1 clinical development. go.novartis.social/4fgFW6o
Novartis Biomedical Research and the @dundeeuni Drug Discovery Unit (DDU) are collaborating to advance drugs to help address global health challenges, including an antimalarial that targets dormant parasites, and an anti-viral for pandemic preparedness. novartis.social/6019WG8jN
In @NatureMicrobiol, researchers describe a potential pediatric drug candidate for #cryptosporidiosis, a neglected disease that causes severe diarrhea, prolonged illness, and even death in young children and other vulnerable populations worldwide. novartis.social/6015mxXuX
The President of Novartis Biomedical Research, @FionaHMarshall, talks about curiosity and collaboration, and her focus on developing “platforms for productivity” that build upon company successes to produce a robust portfolio of medicines for patients. go.novartis.social/4d9PTRQ.
Novartis and Versant Ventures launch Borealis Biosciences, a discovery-stage biotech focused on developing next-generation RNA medicines for kidney diseases. go.novartis.social/4dxm92o
Novartis, Dren Bio sign collaboration agreement to discover, advance antibody-based immune cell engagers for certain cancers, building on Novartis efforts to explore a range of modalities and approaches to bring transformative therapies forward for patients.
Applications are being accepted for the Novartis Data Science Innovation Fellowship Program. If you are a recent PhD grad with a passion for #datascience & #AI and are interested in a career helping patients by advancing #drugdiscovery, apply by July 29.
Our researchers share a new approach for the potential treatment of #sicklecelldisease: using molecular glue degraders to break down a novel protein that suppresses fetal hemoglobin levels. Read their paper in @ScienceMagazine
In @aplbioeng, Novartis researchers unveil a new device that enables high-throughput screening of stretched cells to better understand how they respond under mechanical stress and inform drug discovery. #mechanobiology
Novartis, PeptiDream have entered into an agreement to expand their discovery collaboration aimed at identifying novel peptides for potential use in radioligand therapy and other contexts
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Yesterday, Novartis and @MedsforMalaria announced positive data from the CALINA study exploring a potential medicine formulated for the smallest babies with #malaria, for whom there is currently no evidence-based treatment.
Novartis has entered into a transaction with @ArvinasInc, including a global license agreement for the development and commercialization of an androgen receptor (AR) degrader which is in clinical development for prostate cancer.
#NEWS: Arvinas ($ARVN) enters into a transaction with @Novartis, including a license agreement for Arvinas’ second generation PROTAC® androgen receptor (AR) degrader.
Read the full press release here: rb.gy/pvjft6
Novartis has exercised its option to acquire IFM Due, advancing a collaboration started in 2019 to innovate novel STING antagonists with the potential to address unmet needs in inflammation-driven diseases. novartis.social/6017ci8ZW
I’m excited to share that we’re entering a strategic research collaboration with Isomorphic Labs to use state-of-the-art #AI technologies—including the next-gen model of AlphaFold—to discover novel small molecule therapeutics for select biological targets. storage.googleapis.com/isomo…