Key Paediatric Intensive Care articles all-in-one-place @Dr_Hari_Krishna @OsamaHosheh @DrToyinOcholi picujournalwatch.com #PedsICU **PICCHub app**
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#PedsICU #Bestof2024 collection has just been published. Put together by @OsamaHosheh @DrToyinOcholi @Dr_Hari_Krishna with inputs and spanish translation from @sgdambrauskas. The collection includes 33 articles. Pubmed collection [bit.ly/PedsICU_Bestof2024] has 32 articles
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Just published in JAMA at #CCR26 the GASTRIC-PICU trial results showing that NOT measuring GRV routinely in ventilated PICU patients was safe and increased nutritional achievement jamanetwork.com/journals/jam…
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PICU Journal Watch #PedsICU #PedsCICU retweeted
Jun 11
📊 Research Summary: Sodium bicarbonate did not improve sustained return of spontaneous circulation or survival in adults with in-hospital cardiac arrest, supporting guidelines against its routine use.
#CCR26 @CritCareReviews
ja.ma/445H0GE
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PICU Journal Watch #PedsICU #PedsCICU retweeted
#CCR26 Delve into the ACCOMPLISH trial - published today in JAMA Network Open
👇
jamanetwork.com/journals/jam…
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PICU Journal Watch #PedsICU #PedsCICU retweeted
Day1 at #CCR26
#LOGICALtrial: conservative O₂ after cardiac arrest
#MARCHtrial: carbocisteine /or HTS for airway secretions
#VICTORYtrial: high-dose IV vitaminC in burns
None improved outcomes; MARCH and VICTORY➡️possible harm!
✅#TeleRehabTrial: in AHRF pts, ⬆️QoL ⬇️mortality
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PICU Journal Watch #PedsICU #PedsCICU retweeted
Jun 10
📊 Research Summary: High-dose intravenous #VitaminC did not improve mortality or organ function in adults with severe burns and may increase risk of adverse outcomes, supporting the removal of vitamin C from acute burn protocols.
#CCR26 @CritCareReviews
ja.ma/4uso0gr
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Jun 10
💬 Editorial by David Greenhalgh, MD: High-dose intravenous #VitaminC did not reduce organ dysfunction or mortality in patients with large burns and may increase mortality, supporting its removal from standard burn resuscitation protocols.
#CCR26 @CritCareReviews
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PICU Journal Watch #PedsICU #PedsCICU retweeted
Jun 10
In adults with acute respiratory failure requiring #MechanicalVentilation, an integrated telehealth-based rehabilitation intervention improved 90-day quality of life and reduced mortality compared with usual care.
#CCR26 @CritCareReviews
ja.ma/43pBv5y
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Jun 10
📊 Research Summary: In mechanically ventilated adults with acute hypoxemic respiratory failure, integrated telehealth-based rehabilitation improved 90-day quality of life mainly by reducing mortality, with similar survivor outcomes vs usual care.
#CCR26 @CritCareReviews
ja.ma/43mVEt5
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PICU Journal Watch #PedsICU #PedsCICU retweeted
🚨 Just published in @NEJM and presented at #CCR26.
The #ARISEFLUIDStrial (n=1,000) found that early vasopressors with restricted fluids did not improve days alive and out of hospital at 90 days vs a more liberal fluid strategy!
⚠️ Less pulmonary edema, though (0.6% vs 5.0%)!
ALT DHOH90 76 vs 76, MD 0.0, p=1.00
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PICU Journal Watch #PedsICU #PedsCICU retweeted
#CCR26 the manuscript is now live @nejm and this mornings session is chaired by the journal's very own deputy editor Dr Darren Taichman
Discussion to follow!
nej.md/3PVdwIp nejm.org/doi/full/10.1056/NE…
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Original Article: Carbocisteine or Hypertonic Saline for Acute Respiratory Failure (phase 3 MARCH trial) nej.md/3PUyHdA
#CCR26 | @CritCareReviews
ALT Kaplan-Meier curves comparing duration of mechanical ventilation. Chart A compares carbocisteine (CS) versus no CS, while Chart B compares hypertonic saline (HTS) versus no HTS.
ALT Kaplan-Meier curves illustrating the duration of mechanical ventilation for survivors. Graph A compares carbocisteine (CS) versus no carbocisteine. Graph B shows hypertonic saline (HTS) versus no hypertonic saline.
ALT Kaplan-Meier curves showing the duration of mechanical ventilation over time for non-survivors. Graph A compares carbocisteine (CS) versus no CS. Graph B compares hypertonic saline (HTS) versus no HTS. Both graphs measure duration of mechanical ventilation on the x-axis and probability of ventilation on the y-axis.
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PICU Journal Watch #PedsICU #PedsCICU retweeted
Jun 11
📊 Research Summary: Sodium bicarbonate did not improve sustained return of spontaneous circulation or survival in adults with in-hospital cardiac arrest, supporting guidelines against its routine use.
#CCR26 @CritCareReviews
ja.ma/4ojdDKB
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Presented at #CCR26:
Among patients who were unresponsive after cardiac arrest, conservative oxygen therapy did not increase 180-day survival with favorable function as compared with liberal oxygen therapy. Full LOGICAL trial results: nej.md/4x7TavY
@CritCareReviews
ALT A chart comparing GOS-E results for conservative and liberal oxygen treatments. Both bars display percentages of patients across categories: death (dark gray), vegetative state (red), lower severe disability (orange), upper severe disability (tan), lower moderate disability (dark green), upper moderate disability (green), lower good recovery (blue), and upper good recovery (light blue).
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HOPE for children: successful pediatric DCD #heart #transplantation using hypothermic oxygenated perfusion - The Journal of Heart and Lung Transplantation jhltonline.org/article/S1053… #PedsICU #PedsCICU
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Get ready for the 35th International Congress of the European Society of Paediatric and Neonatal Intensive Care happening on 16–19 June 2026 in Valletta, Malta! Join online or in person for cutting-edge science and global collaboration. Don't miss out! 👉mcascientificevents.eu/espni…
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Jun 8
The latest (May collection) from @PICJournalWatch is now on this link picujournalwatch.com/journal….. ReLiSCh-II trial is the Article of the Month picujournalwatch.com/journal… @Dr_Hari_Krishna @DrToyinOcholi #SEPSIS #Resuscitation #ECMO
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PICU Journal Watch #PedsICU #PedsCICU retweeted
Response to Letter Regarding Article “Impact of Nimodipine-Induced Blood Pressure Reductions on Cerebral Autoregulation and Functional Outcome after Aneurysmal Subarachnoid Hemorrhage" by Petersen et Stoehr
Link: link.springer.com/article/10…
@neurocritical #neurocritcare
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One year quality of life outcomes in critically ill children: a multicenter prospective cohort study | Critical Care | Springer Nature @Crit_Care link.springer.com/article/10… @StudyOceanic #PedsICU
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Maria et al: Evaluation of a Novel Automated Cerebral Ventricular Drainage System for Intracranial Pressure Monitoring and Cerebrospinal Fluid Drainage in NCC Patients: A Prospective, Randomized Clinical Study
Link: link.springer.com/article/10…
@neurocritical #neurocritcare
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enjoyed reading "brain in the line of fire" collection @yourICM @chiara_robba et al., #NeuroPICU #PedsICU #ICP link.springer.com/collection…
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