We’re interested in understanding how plants activate and fine-tune their innate immune responses towards invasive (host-adapted) biotrophic pathogens.

Joined July 2015
53 Photos and videos
nature.com/articles/s41586-0… "Balanced plant helper NLR activation by a modified host protein complex" Fine tuning of immune responses

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Bioinformatics and functional analysis of EDS1 genes in Brassica napus... sciencedirect.com/science/ar…

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Parker Lab retweeted
📢NEW #Preprint ‼️ Magnum opus of @MarionClavel4 w/ excellent help from many amazing people. Keywords: #autophagy #viruses #modified_self_recognition #immune_signaling. Please let us know what you think.🧵 summarising our key findings
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IN BRIEF: From algae to apples: The structural and functional conservation of NLRs (Michael Busche, Bradley Laflamme) buff.ly/3QmUHL7 @JohnInnesCentre @Khongsam_Chia @Phil_Carella @ASPB #PlantSci
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Parker Lab retweeted
Congratulations Jane Parker of @mpipz_cologne, newly inducted NAS international member! #NAS161 #NASmember #genetics #plantbiology
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25 Apr 2024
As part of the #50YearsofCell, our focus issue on Immunology is out! ⁠ ⁠ This issue brings Cell’s 50th anniversary celebrations straight to your lymph nodes with reviews, perspectives and more thought-provoking articles on topics ranging from innate immunity to plant immune systems, and immunological strategies for bacterial detection. ⁠ ⁠ In addition, it features research articles on the mapping of the microbiome across metastatic cancers, a time-series reconstruction of human centriole assembly and how an inhibitory ligand acts directly on CD3e to boost tumor-specific T cell cytotoxicity and limit tumor growth.⁠ ⁠ ⁠To read more click here 👉 cell.com/cell/current
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The N-terminal domains of NLR immune receptors exhibit structural and functional similarities across divergent plant lineages (Khong-Sam Chia, Jiorgos Kourelis, Albin Teulet, et. al.) buff.ly/3JhE67n @JohnInnesCentre @Khongsam_Chia @Phil_Carella @ASPB #PlantSci
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Parker Lab retweeted
📣New publication out by Schulze-Lefert and Chai @mpipz_cologne @Westlake_Uni on how phase separation plays a role in the immune system of #plants. Now published in @Nature Congratulations! 🥳👏👏 Learn more 👉bit.ly/3PHLH31 #Immunology nature.com/articles/s41586-0…
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Substrate-induced condensation activates plant TIR domain proteins @Nature nature.com/articles/s41586-0…

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A plant immunity protein interacts with a fungal cell wall–degrading enzyme to create immunogenic compounds, according to a new study in Science. Learn more ⬇️ 📄: scim.ag/5Xa #SciencePerspective: scim.ag/5X9
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Our story on the origin and evolution of plant PRRs is out @NatureComms ! nature.com/articles/s41467-0… A short & illustrated summary of this story:

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21 Jul 2023
First major paper accepted from the saur lab: tinyurl.com/mv3zjtxr We demonstrate atypical AVR effector function: inhibition of the barley MLA13 NLR by the AVRa13-V2 variant. Thx to the editor and reviewers for their suggestions. With @MerleBS4 & @Emma_Crean_

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Parker Lab retweeted
The @ISMPMI meeting is coming to an end: Plenary Session 8 (chaired by @ParkerLab_MPIPZ) is kicking off with @kseniakrasileva, talking about biodiversity of plant innate immune receptors and pathogen effectors #2023ISMPMI
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Parker Lab retweeted
Great experience on the first day of #2023ISMPMI ! I will present a poster related to glutamate receptor-like channels(GLRs) promoted host cell death in ETI on Monday. Looking forward to seeing you tomorrow at P-166 in Immune Receptors II session during 12:30-13:15.
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Join us at #2023ISMPMI Wednesday after lunch! In addition to learning about new scientific approaches and findings, you’ll have the chance to virtually interact in the session. 📱🛜
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Let's unravel the secrets of signal exchange, metabolic shifts, and microbial community dynamics! Don't miss the eye-opening #2023ISMPMI Concurrent Session 14 on the fascinating world of plant-microbe interactions through chemical compounds. events.rdmobile.com/Sessions…
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Please visit her talk and poster. #2023ismpmi #mlkl #concurrentsession1
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