In @elife: Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C doi.org/10.7554/eLife.94869.
Finally out! A great collaboration with Priit Eek and Song Tan.
Fantastic cryoEM structure of the SRCAP-nucleosome complex from the Wang and Xu groups. We finally see all the subunits! Yu et al. Cell Discovery (2024) 10:15 Cell Discovery
doi.org/10.1038/s41421-023-0…
Just sharing another sad news with the scientific community. The Pioneering molecular biologist Dr. Michael Green, M.D. Ph.D., HHMI and NAS member from Umass Med. School, passed away today with a stroke. Dr. Green revolutionized our understanding of transcription factors. RIP
This feels like posting into the abyss but for any of you that are still following along... our manuscript with @PetersonLab on the mechanism of SWR1C-mediated H2A.Z deposition is now out in Nature Comms.
rdcu.be/cZUup
Our smFRET study on H2A.Z deposition is finally out in Nature Communications! It took nearly 10 months but I think the final product was worth the pain. Fantastic collaboration with Joe Loparo and Andrew Moreno at HMS. nature.com/articles/s41467-0…