Today’s the day! The H-SPAN Summit D.C. agenda is officially LIVE! Check out our incredible lineup of sessions and speakers here: a4li.org/h-span-summit-dc/ Let us know who you’re most excited to see by commenting below! For the next week, get 20% off a ticket using promo code: HEALTHSPAN

⚡️The von der Leyen quote is one of the most revealing things a European leader has said in the last decade and almost nobody is going to process it correctly. “The cheapest energy is the one you don’t use.” That is a sentence spoken by a person presiding over civilizational decline who has decided to reframe the decline as virtue. It’s not a policy statement. It’s a theological position. The energy crisis isn’t a problem to be solved by producing more energy. It’s an opportunity for Europeans to need less. To want less. To consume less. To live smaller lives in smaller apartments heated to lower temperatures with less travel and less activity and less economic output. The scarcity isn’t a failure. It’s the goal. This is the thing Americans and everyone outside of Europe cannot fully grasp about where European elite thinking has landed. They genuinely believe that reducing European energy consumption is morally good regardless of the economic consequences, because European consumption is tied to European environmental guilt which is tied to European colonial guilt which is tied to a broader belief that European civilization has been net negative for the world and should shrink. The energy crisis gives them political cover to implement policies that would otherwise be unpopular. Now they can say circumstances force the reduction when the reduction was always the plan. Von der Leyen is not an aberration. She represents the consensus view among the European political class. Macron believes this. Scholz believes this. The entire EU Commission believes this. They don’t say it this directly usually because it polls badly, but every major policy they implement is consistent with this worldview. Degrowth is not a fringe academic position in European politics. It’s the operating framework at the top. The American version of this framing would be “the cheapest energy is the one we produce ourselves at scale.” That’s what actually reduces cost and increases resilience. Building more nuclear, extracting more gas, expanding the grid, investing in new production. The European version is the opposite. Don’t build anything. Don’t extract anything. Don’t produce anything. Just use less. And when citizens can’t heat their homes or fly for work, frame it as virtue. This is why Europe can’t recover from the current trajectory. The recovery would require a complete reversal of the ideological framework that produced the decline, and that framework is held most strongly by exactly the people who have the power to change it. They’re not going to reverse it because they don’t see the trajectory as a problem. They see it as necessary and good.

John G Cramer is set to be the first person to receive lab-grown mitochondria as part of a pioneering longevity trial from Mitrix Bio. longevity.technology/news/ph… #longevity #biotech #mitochondria #agex #healthspan #clinicaltrial #biohacking #futureofaging

BREAKING: Honoured to share that I’ve been appointed Chief Medical and Scientific Advisor to Make Europe Healthy Again. Tomorrow we launch in the European Parliament where I’m delivering a keynote with @RWMaloneMD This is an incredible effort spearheaded by the brilliant @MAHUMO20 & @DrAndreaPhD This organisation is independent of political influence that will fight ensure the highest standard of ethical evidence based medical practice and public health policy is implemented for individuals and populations. This will be live-streamed from 2 - 6pm CET October 15th. Click on this link to watch gomeha.com/

The Asia-Pacific Longevity Medicine Summit is proud to announce the WINNERS of the 2025 TOP 10 Longevity Breakthrough Awards: 1. NuSirt Sciences, USA 2. ADvantage Therapeutics, USA 3. Circulate Health, USA 4. Halia Therapeutics, USA 5. Yuva Biosciences, USA 6. Tracked Biotechnologies, USA 7. Exhale Science, USA 8. Ekeilabs, Japan 9. Tianyicare, China 10. Vasa Therapeutics, USA During the Summit, all participants will have the opportunity to select the "Best of the Best" from among these distinguished winners(apaclongevitysociety.org)

1 month until Longevity Nation - Israeli Longevity Alliance (ISRLA) Speakers include: @ILAISRLA @KrizhanovskyLab @BiskupEwelina @GrunewaldMyriam @marioskyriazis @PetrSramekBench @cordeiro #AgingResearch #Longevity #Rejuvenation liveforever.club/events?sele…

$10,000 for a meme?! P(doom), the paperclip maximizer, Black Mirror, Brave New World, and 1984 are common references for dystopian futures. But where are the hopeful ones? For abundant clean energy, infinite knowledge, no infectious disease, no poverty, solved aging, and effective global coordination? Today, we’re excited to launch the Meme Prize: a $10k award for the best new meme that conveys a positive future. Submit your meme: existentialhope.com/existent…

Two-day summit seeks to accelerate the integration of rigorously tested longevity interventions into clinical practice. longevity.technology/news/ho… #longevity #agingwell #healthspan #biotech #HongKong

🚨 PYM’s Aisha: How to Disrupt the F-35 Program This may be the most alarming thing to come out of the People’s Conference for Palestine because it is a step-by-step playbook that America’s enemies could benefit from. Aisha, a leader with the Palestinian Youth Movement, explained how activists could cripple the U.S. military’s crown jewel fighter jet program, the F-35: “70% of the cost of the F-35 program actually comes from the supply chain… It functions off of this just-in-time logistics process… If one specific node of the F-35 supply chain is intervened in, it has a huge impact.” She pressed the audience to study the system and attack weak points with precision: “We need to be surgical. We need to be strategic. And we need to be bold in our actions. Because there are many different points of these supply chains of death that we can intervene in and we must intervene in.” This is an operational roadmap for undermining U.S. defense readiness. Framed through Palestine, the implications reach far beyond. Imagine a global conflict where anti-American activists, taking these words literally, set out to sabotage the logistics of America’s crown jewel weapons systems. I cannot overstate how radical and dangerous this really is.

Nominate your longevity startup/company to showcase and investor talks in Hong Kong and get access to the vast ASIA market. longevityawards.org

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SCIENTISTS FOUND A “YOUTH PROTEIN” — AND IT WORKED IN 1 SHOT (ON MICE) Scientists hit mice with one dose of s-KL, a protein tweak that boosted muscle strength, bone density, neurogenesis, and lifespan. No supplements. Just gene therapy. Klotho, named after the Greek Fate who spun the thread of life (no pressure), regulates FGF23, Wnt, and IGF-1 — aka the biological control panel for aging. Males bulked up and lived longer. Females got denser bones. Hormones probably interfered, as usual. Older mice responded better than younger ones. Apparently, being slightly broken is a requirement for repairs to work. Bonus: less neuroinflammation, more hippocampal neurons, better brain function. Basically, they turned tired mice into overachievers. Still no human trials. For now, immortality is mouse-exclusive. Source: Molecular Therapy, Earth Magazine

Genflow begins SIRT6 gene therapy trial in dogs. Trial aims to demonstrate capacity to extend healthspan in older animals as company continues to progress towards human trials. longevity.technology/news/ge…

The Multiscale Wheeler Game open.substack.com/pub/sramek…

Co s vámi udělá 9 měsíců na oběžné dráze? Nemluví se o tom ale ve vesmíru stárneme zhruba 30 krát rychleji než na zemi. Naštěstí dokážeme část toho zrychleného stárnutí zvrátit. Pokud chcete vědět více, připojte dotazy.

Introducing Helix, our newest AI that thinks like a human To bring robots into homes, we need a step change in capabilities Helix can generalize to any household item 🧵

We have a new record. Spike protein present 709 days post vaccination! @GWR It’s not normal for protein to stick about this long. Have a look at what ChatGPT has to say about that below. medrxiv.org/content/10.1101/…